Clinical trials
Postoperative Pain clinical trials
Below are recruiting postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 539 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06189781RecruitingPhase 4
Pain shot vs epidural for hip surgery in kids with cerebral palsy
This study compares a pain injection to epidural anesthesia for children with cerebral palsy having hip surgery. The goal is to see which method provides better pain control during and after the procedure.
Los Angeles, CaliforniaAges Up to 18 years - NCT07461467Recruiting
Managing breathing tube pressure to reduce throat problems in older adults
This study tests a way of managing the air pressure in a breathing tube mask used during surgery. The goal is to reduce throat and voice box problems after surgery in older patients.
Chongqing, Chongqing MunicipalityAges 60 years+ - NCT07401641Recruiting
Pain control study for oral cancer surgery
This study tests two different pain medicines (dezocine or nalbuphine) combined with sufentanil to see which helps better control pain after oral cancer surgery with free flap reconstruction. It also looks at side effects and how well the transplanted tissue survives.
Guangzhou, GuangdongAges 18–70 - NCT06559215RecruitingPhase 2
Pain management with Exparel after knee surgery in teens
This trial is testing a long-acting numbing medicine called Exparel to see how well it controls pain after a specific knee surgery (MPFL reconstruction) in teens and young adults. It may help reduce the need for strong painkillers after the operation.
Frisco, TexasAges 13–21 - NCT07441421Recruiting
Improved pain relief for brain tumor surgery
This study tests a combination of pain-relief methods given before, during, and after brain surgery to see if they better control pain and help you recover with fewer side effects. It's for adults having surgery to remove a brain tumor.
BeijingAges 18–65 - NCT06997016Enrolling by invitationPhase 4
Recovery program for living donor kidney transplant
This trial tests a special recovery program (ERAS) for people who get a kidney from a living donor. The program aims to help you heal faster and feel better after surgery.
Fort Worth, TexasAges 18 years+ - NCT03625011RecruitingPhase 4
Gabapentin before tonsil surgery to reduce pain
This trial tests whether giving gabapentin before pediatric tonsil (and possibly adenoid) removal can reduce postoperative pain. It may help children feel more comfortable after surgery while still being safe to use in the right patients.
Atlanta, GeorgiaAges 3–18 - NCT06205355Recruiting
Pain measurement tool for jaw surgery patients
This study tests a device that measures your body's response to pain during jaw surgery. It may help doctors better manage your pain during and after the procedure.
SeoulAges 18 years+ - NCT07868315Recruiting
Single-visit root canal pain and success comparison
This study compares pain after a single-visit root canal treatment using different sealers (materials used to fill the root canal) in asymptomatic (pain-free) teeth. It aims to find which sealer causes less discomfort and has a better success rate.
Istanbul, EsenlerAges 18–65 - NCT07867951Recruiting
Pain after two root canal medicines
This study compares two medicines placed inside a tooth during root canal treatment to see which one reduces pain better afterward. It may help people with an infected tooth causing pain.
Swāt, KpkAges 16–50 - NCT07857655RecruitingPhase 4
Intraoperative methadone for pain after head and neck cancer surgery
This trial tests whether giving methadone during your head and neck cancer surgery helps control pain right after the operation. Methadone is a long-acting painkiller that might reduce pain for up to a day or more, potentially improving your recovery experience.
Portland, OregonAges 18–89 - NCT06405776Recruiting
Lidocaine for pain and survival after bowel surgery in older adults
This study tests whether a drug called lidocaine, given during surgery, can help control pain after colon or rectal surgery and possibly improve long-term survival in older adults. The goal is to see if lidocaine offers better pain relief and recovery compared to standard care.
SichuanAges 60 years+ - NCT07840183RecruitingPhase 4
Epidural versus other pain relief for open ventral hernia repair
This study compares two ways to manage pain after hernia repair surgery: using an epidural (a small tube in your back that delivers pain medicine) versus other pain medications that aim to reduce opioid use. The goal is to see which method provides better pain relief and helps you recover more comfortably.
Chicago, IllinoisAges 18–80 - NCT07826741Recruiting
Pain relief options for open inguinal hernia surgery
This study compares two ways to manage pain after open inguinal hernia repair: a spinal injection of morphine and a numbing injection near the abdomen. The goal is to find which method provides better pain relief with fewer side effects.
Yenimahalle, AnkaraAges 18–80 - NCT07818954Recruiting
Nerve block near the belly for gallbladder surgery
This study tests a numbing injection (called a subcostal TAP block) given near the belly to see if it affects brain activity during gallbladder surgery. It may help improve pain control and anesthesia care.
IstanbulAges 18 years+ - NCT07819630Recruiting
Skin stimulation effects on brain activity during abdominal surgery
This study is testing whether a gentle, non-invasive electrical stimulation on specific points on your skin (called acupoints) can affect the brain's electrical activity during abdominal surgery under general anesthesia. It may help researchers understand how this therapy works and potentially improve recovery in the future.
BeijingAges 18–80 - NCT06341270Recruiting
Electric acupressure for pain after liver surgery
This trial tests if a gentle electric stimulation on the skin (TEAS) can reduce pain and speed up recovery after liver surgery. The treatment is non-invasive and may be an alternative to pain medicines.
Chengdu, SichuanAges 18–80 - NCT07808684Recruiting
Comparing root canal file designs on debris removal
This study tests two different root canal file designs to see which one removes debris better from the end of the root. It may help people who need a root canal on a tooth with a single root canal.
Minya, Minya GovernorateAges 20–40 - NCT07787221Recruiting
Pain relief blocks after kidney removal surgery
This study compares two types of nerve blocks to see which one provides better pain relief after surgery to remove a kidney. If you are having this surgery, the results may help your doctors choose the best way to manage your pain.
CairoAges 18–65 - NCT07783386Recruiting
Comparing nerve block volumes for breast surgery pain
This study compares different volumes of a nerve block (SPSIP) for pain relief after breast surgery. It aims to see if one volume provides better pain control with fewer side effects.
Nilufer, BursaAges 18–75 - NCT07775053Enrolling by invitation
Pain relief study for breast cancer surgery
This study tests whether adding tramadol to a standard numbing medicine (ropivacaine) makes pain control better after breast cancer surgery. If you're having a mastectomy, this could help reduce pain and improve recovery.
Sargodha, Punjab ProvinceAges 20–70 - NCT07770932Recruiting
Pain relief after hip replacement surgery
This study compares two types of nerve blocks for pain relief after hip replacement surgery. It aims to find which method reduces pain and improves recovery.
Istanbul, BagcilarAges 18–80 - NCT07765095Recruiting
Nerve block for pain after hip socket surgery
This study tests a numbing injection around the hip socket to see if it reduces pain after surgery to fix a broken hip socket. It may help you feel better and need less pain medicine after your operation.
San JuanAges 18 years+ - NCT07766031Recruiting
Comparing endoscopic and open surgery for herniated disc pain
This study compares two types of surgery for a herniated disc in the lower back: endoscopic (using a small camera) and open surgery. It aims to see which approach leads to less pain and less need for painkillers after the operation.
Saint-GrégoireAges 18 years+
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Common questions
- Are there clinical trials for postoperative pain?
- Yes. Clin2 currently lists 539 recruiting postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain, Acute
- Postoperative Pain Management
- Chronic Postoperative Pain
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.