Clinical trials
Postoperative Pain clinical trials
Below are recruiting postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 538 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07779551Enrolling by invitation
Pain relief after thyroid surgery: comparing two numbing drugs
This study compares two medications, bupivacaine and ropivacaine, given as a neck block before thyroid surgery to see which provides better pain relief after the operation. It may help reduce post-surgery discomfort.
Sargodha, Punjab ProvinceAges 20–40 - NCT07704970Recruiting
Nerve block for pain relief in robotic kidney surgery
This trial tests a special nerve block called QLESP to control pain after robotic partial kidney removal. It may reduce the need for strong pain medicines and improve recovery.
Wuhan, HubeiAges 18–80 - NCT07392099Recruiting
Comparing a single pain relief class vs. usual care after orthopedic surgery
This study tests whether a single, 1-hour class on pain management (called Empowered Relief) can help people recover better after orthopedic surgery (like hip or knee replacement) compared to usual care. It is for people who have had moderate to severe pain for at least 3 months and are fluent in French.
Sherbrooke, QuebecAges 18 years+ - NCT06838039Recruiting
A second nerve block for less pain after lung surgery
This study tests whether adding a second nerve block (serratus anterior block) within 24 hours after a lung surgery (VATS) can reduce pain better than the standard nerve block alone. It aims to help patients control pain with fewer strong painkillers.
HebronAges 18–70 - NCT06757075RecruitingPhase 4
Managing pain after children's dental surgery
This study tests different ways to manage pain in young children after dental surgery done under general anesthesia. It aims to find the best method to keep children comfortable and reduce discomfort.
Brighton, MassachusettsAges 4–6 - NCT06753500RecruitingPhase 4
Numbing medicine during gallbladder surgery
This trial tests whether giving a special numbing medicine during gallbladder surgery helps reduce pain. It is for adults having laparoscopic (minimally invasive) gallbladder removal.
Barranquilla, AtlantivoAges 18 years+ - NCT06710405RecruitingPhase 4
Lidocaine for pain relief after children's chest surgery
This trial tests whether giving lidocaine during surgery can reduce pain and speed up recovery in children under 7 having chest surgery with a camera. If it works, it could mean less pain and a faster return to normal after the operation.
SeoulAges 6 months–7 years - NCT07247929Recruiting
Pain and swelling after third molar surgery
This trial compares two surgical methods for removing partially impacted wisdom teeth to see which causes less pain and swelling afterwards.
Islamabad, IslamabadAges 18–45 - NCT06917300Recruiting
Virtual reality to reduce pain and anxiety before spine surgery
This trial tests if using virtual reality before surgery can help reduce pain and anxiety in people having elective spine surgery. If you're scheduled for spine surgery and speak Polish, you may be able to participate.
Lodz, Łódź VoivodeshipAges 25–70 - NCT06975761RecruitingPhase 2
Comparing two root canal fillings for pain
This study compares two types of root canal filling materials to see which one is better at reducing pain after the procedure. If you have a painful lower back tooth that needs a root canal and you are a healthy man aged 20-40, you may be able to join.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT07441902Recruiting
Numbing medicine for lung surgery pain relief
This trial tests whether a numbing medicine (liposomal bupivacaine) injected near the ribs can reduce pain after lung surgery. If you qualify, you may experience less pain and need fewer painkillers after your operation.
Beijing, Beijing MunicipalityAges 18–64 - NCT07432711Recruiting
Liposomal bupivacaine for pain after lung surgery
This trial tests if a long-acting numbing medicine called liposomal bupivacaine can reduce pain after video-assisted lung surgery. It aims to help patients feel better after the procedure with less need for other painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT07388745Recruiting
Comparing two pain blocks for heart bypass surgery
This study compares two different nerve-block injections (one near the spine, one under the shoulder blade) to see which provides better pain relief after heart bypass surgery. If you are scheduled for a planned bypass and are in reasonably good health, you might be able to join.
KütahyaAges 45–85 - NCT07353996RecruitingPhase 4
Finding the right dose of a new IV painkiller after bone surgery
This trial tests a single dose of a new pain medicine called tegileridine fumarate given through a vein right after orthopedic surgery (like spine, hip, or knee surgery). The goal is to find the best dose that works well for pain without causing side effects.
Hanzhong, ZhejiangAges 18–75 - NCT06903819RecruitingPhase 4
Ketamine for pain and mental health after orthopedic injury
This trial tests if ketamine can reduce pain, opioid use, and improve mental health in adults recovering from serious orthopedic injuries. It may help those with high injury severity scores.
Lubbock, TexasAges 18–65 - NCT07800364Recruiting
Tizanidine before leg surgery for better pain and sleep
This study tests whether taking a muscle relaxant called tizanidine before leg surgery improves pain control and sleep quality after the operation. It may help you recover more comfortably.
Tanta, Gharbia GovernorateAges 21 years+ - NCT07360028Recruiting
Nerve blocks for pain after chest surgery
This trial tests two types of numbing injections (nerve blocks) to control pain after chest surgery done with a camera. It aims to find which block works better so you can recover more comfortably.
Cairo, Abbassia-EgyptAges 25–70 - NCT07134660Recruiting
Comparing two numbing medicines for lung surgery pain
This study compares two types of numbing medicine (liposomal vs. hydrochloride bupivacaine) injected near the ribs during lung surgery. The goal is to see which one provides better pain relief after the operation.
ShanghaiAges 18–80 - NCT07041736Recruiting
Laser combo for pain and infection after root canal
This trial tests if using ultrasound and a 980 nm diode laser together can reduce pain and kill bacteria better after a root canal. It may help if you have a tooth with an infection at the tip, but no symptoms.
CairoAges 20–35 - NCT06471348Recruiting
Pain control after scoliosis surgery: comparing two numbing medicines
This study compares two types of numbing medicine used during scoliosis surgery to see which provides better pain relief after the operation. One is a long-acting version (liposomal bupivacaine) and the other is a standard short-acting mix (bupivacaine with epinephrine). If you are a teen having surgery for Adolescent Idiopathic Scoliosis, this trial may help find a way to reduce pain and possibly lessen the need for opioids afterward.
Boston, MassachusettsAges 10–17 - NCT06909851Recruiting
Comparing nerve blocks for pain after knee arthroscopy
This study compares two different types of nerve blocks to see which provides better pain relief after arthroscopic knee surgery. You will receive one of the blocks after your surgery, and your pain levels will be tracked.
IstanbulAges 18–72 - NCT07057557Recruiting
Aloe vera vs paraffin dressing for skin graft pain
This trial compares aloe vera dressing with paraffin tulle dressing to see which one reduces pain better at the area where a skin graft was taken. If you need a skin graft and are not allergic to either dressing, this study may help find a gentler way to manage your pain.
Lahore, Punjab ProvinceAges 18–60 - NCT06456268Recruiting
VibraCool to reduce pain and opioid use after ACL surgery
This trial tests a device called VibraCool to see if it can reduce pain and the need for opioid painkillers after ACL reconstruction surgery.
New York, New YorkAges Any age - NCT06189781RecruitingPhase 4
Pain shot vs epidural for hip surgery in kids with cerebral palsy
This study compares a pain injection to epidural anesthesia for children with cerebral palsy having hip surgery. The goal is to see which method provides better pain control during and after the procedure.
Los Angeles, CaliforniaAges Up to 18 years
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Common questions
- Are there clinical trials for postoperative pain?
- Yes. Clin2 currently lists 538 recruiting postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain, Acute
- Postoperative Pain Management
- Chronic Postoperative Pain
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.