Clinical trials
Postoperative Pain clinical trials
Below are recruiting postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 562 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06968065Recruiting
Pain control after minimally invasive heart surgery: nerve block vs wound injection
This study compares two ways to manage pain after minimally invasive heart surgery: a nerve block injection near the ribs or injecting numbing medicine into the wound. The goal is to find which method works better for reducing pain and your need for painkillers.
IstanbulAges 18–75 - NCT07164677Recruiting
Nerve block for pain after open-heart surgery
This study tests a nerve block (an injection near the back muscles) to see if it helps control pain after open-heart surgery. It might be a good option if you are having planned heart surgery through a cut in the middle of your chest.
SamsunAges 18–80 - NCT07442539Recruiting
Numbing medicine for pain after hemorrhoid surgery
This trial tests a long-acting numbing medicine called liposomal bupivacaine to see if it reduces pain after hemorrhoid surgery better than standard care. It may be an option for people who are otherwise healthy and scheduled for this surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT06381063RecruitingPhase 3
Anti-inflammatory for heart surgery
This trial is testing whether a non-steroidal anti-inflammatory drug (NSAID) given during heart surgery can reduce complications. It's for people having planned open-heart surgery with a heart-lung machine.
AmiensAges 18 years+ - NCT06517069Recruiting
Acupuncture plus medication for pain after gynecologic surgery
This study tests whether adding a type of acupuncture (TEAS) to pain medication can better control pain after laparoscopic gynecologic surgery. It aims to improve recovery and comfort.
Yangzhou, JiangsuAges 18–65 - NCT07740915Enrolling by invitation
Pain relief after heart surgery in children
This study compares two types of pain blocks for children having heart surgery for the first time. The goal is to see which block provides better pain relief after surgery, which could help your child recover more comfortably.
Diyarbakır, DiyarbakırAges birth–18 years - NCT07723352Enrolling by invitation
Testing Journavx for Thumb Arthritis Surgery Pain
This trial tests a new pain medicine called Journavx (suzetrigine) for people having thumb arthritis surgery. It aims to see how well the medicine controls pain after the operation.
Philadelphia, PennsylvaniaAges 40–80 - NCT07124494Recruiting
Anesthesia type and recovery after knee replacement
This study compares two types of anesthesia for total knee replacement to see which helps with pain, movement, and satisfaction after surgery. If you are scheduled for a knee replacement and are willing to have a spinal or epidural anesthesia, you may be able to join.
Konya, MeramAges 18 years+ - NCT05841290Recruiting
Compare types of dental sealers for post-procedure pain
This study checks how much pain happens after dental procedures using different types of filling/sealing materials. It may help you and future patients understand which sealer options tend to cause less postoperative discomfort.
El Shorouk, Cairo GovernorateAges 18–50 - NCT06522620Recruiting
Nerve block for knee pain after total knee replacement
This trial tests whether a nerve block can reduce pain on the back and outer side of the knee after total knee replacement surgery. If effective, it may help you recover more comfortably.
Yinchuan, NingxiaAges 45–80 - NCT06887153Recruiting
Pain medicine use after major surgery
This study looks at how different pain medicines are used together after major surgery and how well they control pain. It may help improve pain relief for people having planned bone, belly, or chest surgeries.
KampalaAges 18 years+ - NCT07331441Recruiting
Nerve block for pain relief after major upper abdominal surgery
This trial tests a nerve block given near the ribs to see if it reduces pain after surgeries like gastric, liver, gallbladder, or pancreatic surgery. It may help you need less pain medicine after the operation.
ShanghaiAges 18–85 - NCT07223580RecruitingPhase 4
Steroid use for pain after kidney stone surgery
This trial tests if giving a corticosteroid during ureteroscopy (a scope procedure to remove kidney or ureter stones) can reduce pain afterward. If you are having this surgery and are not already on steroids or strong pain medicines, this study may help manage your recovery.
Scottsdale, ArizonaAges 18 years+ - NCT07779551Enrolling by invitation
Pain relief after thyroid surgery: comparing two numbing drugs
This study compares two medications, bupivacaine and ropivacaine, given as a neck block before thyroid surgery to see which provides better pain relief after the operation. It may help reduce post-surgery discomfort.
Sargodha, Punjab ProvinceAges 20–40 - NCT06757075RecruitingPhase 4
Managing pain after children's dental surgery
This study tests different ways to manage pain in young children after dental surgery done under general anesthesia. It aims to find the best method to keep children comfortable and reduce discomfort.
Brighton, MassachusettsAges 4–6 - NCT06838039Recruiting
A second nerve block for less pain after lung surgery
This study tests whether adding a second nerve block (serratus anterior block) within 24 hours after a lung surgery (VATS) can reduce pain better than the standard nerve block alone. It aims to help patients control pain with fewer strong painkillers.
HebronAges 18–70 - NCT07392099Recruiting
Comparing a single pain relief class vs. usual care after orthopedic surgery
This study tests whether a single, 1-hour class on pain management (called Empowered Relief) can help people recover better after orthopedic surgery (like hip or knee replacement) compared to usual care. It is for people who have had moderate to severe pain for at least 3 months and are fluent in French.
Sherbrooke, QuebecAges 18 years+ - NCT06753500RecruitingPhase 4
Numbing medicine during gallbladder surgery
This trial tests whether giving a special numbing medicine during gallbladder surgery helps reduce pain. It is for adults having laparoscopic (minimally invasive) gallbladder removal.
Barranquilla, AtlantivoAges 18 years+ - NCT06710405RecruitingPhase 4
Lidocaine for pain relief after children's chest surgery
This trial tests whether giving lidocaine during surgery can reduce pain and speed up recovery in children under 7 having chest surgery with a camera. If it works, it could mean less pain and a faster return to normal after the operation.
SeoulAges 6 months–7 years - NCT06917300Recruiting
Virtual reality to reduce pain and anxiety before spine surgery
This trial tests if using virtual reality before surgery can help reduce pain and anxiety in people having elective spine surgery. If you're scheduled for spine surgery and speak Polish, you may be able to participate.
Lodz, Łódź VoivodeshipAges 25–70 - NCT06975761RecruitingPhase 2
Comparing two root canal fillings for pain
This study compares two types of root canal filling materials to see which one is better at reducing pain after the procedure. If you have a painful lower back tooth that needs a root canal and you are a healthy man aged 20-40, you may be able to join.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT07247929Recruiting
Pain and swelling after third molar surgery
This trial compares two surgical methods for removing partially impacted wisdom teeth to see which causes less pain and swelling afterwards.
Islamabad, IslamabadAges 18–45 - NCT06447545Recruiting
Comparing air pressure levels for gallbladder surgery pain
This trial compares two different air pressure levels used during laparoscopic gallbladder removal to see which one causes less pain after surgery, including shoulder pain and bile duct injuries.
Lahore, PUNAges Any age - NCT07388745Recruiting
Comparing two pain blocks for heart bypass surgery
This study compares two different nerve-block injections (one near the spine, one under the shoulder blade) to see which provides better pain relief after heart bypass surgery. If you are scheduled for a planned bypass and are in reasonably good health, you might be able to join.
KütahyaAges 45–85
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Common questions
- Are there clinical trials for postoperative pain?
- Yes. Clin2 currently lists 562 recruiting postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain, Acute
- Postoperative Pain Management
- Chronic Postoperative Pain
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.