Clinical trials
Postoperative Pain clinical trials
Below are recruiting postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 538 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06839716Recruiting
Comparing a numbing gel with standard pain block after stomach cancer surgery
This study tests a gel made of ropivacaine (a numbing medicine) in a special hydrogel to see if it works as well as the standard pain block injection (TAP block) for controlling pain after minimally invasive stomach cancer surgery. The gel is applied directly near the surgical wound.
SeoulAges 20 years+ - NCT07369726Recruiting
Mobilization and caffeine after cesarean
This trial tests whether getting out of bed and drinking coffee after a planned cesarean can help reduce pain and speed up recovery. It is for women who have moderate to severe pain after surgery.
Konya, KonyaAges 18–35 - NCT07365800Enrolling by invitationPhase 4
Combination pain control after complex spine surgery
This study tests a combination of three medications (methadone, dexmedetomidine, and ketamine) to control pain after major spine surgery. If you are having complex spine surgery, this trial may offer better pain relief without needing as much opioid medication.
Columbia, MissouriAges 18–79 - NCT07354581Recruiting
Pain blocks after lower back surgery
This trial compares two types of pain-block injections (erector spinae plane block versus quadro-iliac plane block) given during lower back surgery to see which controls pain better. It may help you have less pain and need fewer pain medicines after your operation.
BursaAges 18–65 - NCT07336303Recruiting
Ear acupuncture for thumb surgery pain
This study tests whether ear acupuncture (auriculotherapy) helps reduce pain after thumb arthritis surgery. If you're having this surgery and haven't tried ear acupuncture before, you may be able to join.
ParisAges 18 years+ - NCT05824832RecruitingPhase 4
Buprenorphine, clonidine, and steroid to extend arm nerve block
This study tests whether adding certain medicines (buprenorphine, clonidine, and a steroid) to an arm “nerve block” during shoulder surgery can help the numbness last longer and improve comfort afterward. It is for adults having shoulder arthroscopy and compares how long the nerve block works.
Maywood, IllinoisAges 18 years+ - NCT07316166RecruitingPhase 4
Nerve Block With or Without Extra Medicine for Hip Replacement
This trial compares two types of nerve blocks for pain relief after total hip replacement. One block uses a standard numbing medicine, and the other adds a medication (dexmedetomidine) that may extend the pain relief. The goal is to see which approach works better for managing pain after surgery.
Providence, Rhode IslandAges 18–80 - NCT07310212Recruiting
Comparing two root canal techniques for pain and success
This study compares two methods of filling a root canal after cleaning it: a traditional lateral condensation technique and a newer warm vertical obturation technique. The goal is to see which one causes less pain afterward and has a better success rate.
Amman, Amman GovernateAges 18 years+ - NCT07297784Enrolling by invitation
Screen time and pain after tonsil removal in children
This study looks at whether children who use a lot of screens (like tablets, phones, or TV) feel more or less pain after tonsil surgery. It could help parents understand how media use affects recovery.
Tokat Province, Tokat ProvinceAges 4–11 - NCT03382938Recruiting
Dexmedetomidine injected into C-section wounds
This trial studies whether a specific numbing/comfort medicine (dexmedetomidine) injected into the wound area during a C-section can improve recovery or reduce symptoms after surgery. You may be able to take part if you are a low-risk pregnancy and meet safety requirements.
Athens, OtherAges 18–40 - NCT07283003Recruiting
Pain after ureter stone removal surgery study
This study looks at pain levels after a procedure to remove stones from the ureter (the tube connecting your kidney to your bladder). It may help find better ways to manage pain after surgery.
BadenAges 18 years+ - NCT07287657Enrolling by invitation
Electrical acupoint stimulation after chest surgery
This trial tests a gentle, non-needle therapy that stimulates acupoints with mild electrical current to help you recover better after chest surgery. It may reduce pain and speed healing.
Taipei, HualienAges 15 years+ - NCT07271849RecruitingPhase 4
Timing of Nalbuphine for Pain and Blood Pressure in Older Knee Surgery Patients
This study tests whether giving the pain medicine nalbuphine at different times during knee replacement surgery affects blood pressure and pain control in older adults. It may help find the best timing to reduce pain and keep vital signs stable.
Jinan, ShandongAges 65–90 - NCT06545409Recruiting
Nerve block for pain relief in robotic thymus surgery
This trial tests a nerve block to reduce pain after robotic thymus surgery. It may help patients with thymus growths or cysts have less pain and use fewer painkillers after their operation.
RomeAges 18 years+ - NCT07264699Recruiting
Guided nerve block for hernia repair pain control
This trial tests whether a visually guided nerve block (TAP block) during laparoscopic hernia repair reduces pain and improves recovery. If you are having planned hernia surgery, this study may help you experience less pain after the procedure.
Olsztyn, Warmisko-mazurskieAges 18–80 - NCT07256691Recruiting
Bioceramic vs. resin sealer for root canal pain
This study tests two types of sealing materials used in root canals (a newer bioceramic one vs. a standard resin one) to see which causes less pain after treatment. If you have an infected, pain-free tooth that needs a root canal, this trial may help guide better care.
Lahore, Punjab ProvinceAges 18–55 - NCT07241949Recruiting
Nerve block for gallbladder surgery pain relief
This study tests a nerve block called the external oblique intercostal block to reduce pain after laparoscopic gallbladder removal. If you are having this surgery, the block may help you need less pain medication and feel more comfortable after the procedure.
AdanaAges 18–65 - NCT07242170Recruiting
Comparing nerve blocks for pain after knee replacement surgery
This trial tests if adding extra nerve blocks (sciatic, BiFeS, or IPACK) to the usual adductor canal block can reduce pain after total knee replacement. The goal is to find a better way to manage pain and improve recovery.
Erzincan, MerkezAges 18–75 - NCT07239817Recruiting
Nerve block and local anesthetic for hip replacement surgery
This study tests whether a nerve block plus local anesthetic can improve pain control during and after hip replacement surgery for a broken hip. It may help reduce the need for stronger pain medications and improve recovery.
MilanAges 18 years+ - NCT07221786Recruiting
Opioid reduction before spine surgery
This trial tests whether slowly reducing opioid pain medications before spine surgery can lead to a better recovery afterward. It is for adults already taking daily opioids who have major spine surgery planned at least a month away.
Philadephia, PennsylvaniaAges 18 years+ - NCT06915558Recruiting
Reducing inflammation in weight loss surgery
This trial tests a method to control inflammation during bariatric surgery. It may help patients recover better and have fewer complications.
Barcelona, BarcelonaAges 18–65 - NCT07213375RecruitingPhase 2/Phase 3
High-dose steroid to reduce pain after lung surgery
This trial tests if a high dose of dexamethasone (a steroid) can lower pain after keyhole lung surgery. If you are having planned keyhole lung surgery for a lobe or segment, you may be eligible.
Copenhagen, CopenhagenAges 18 years+ - NCT07219888Enrolling by invitationPhase 4
Comparing suzetrigine and oxycodone for knee replacement pain
This study compares a new pain medicine called suzetrigine with a commonly used opioid, oxycodone, for pain after a knee replacement. The goal is to see which works better and has fewer side effects.
Louisville, KentuckyAges 21–89 - NCT07203859Recruiting
Nerve block for pain after kidney stone surgery
This study tests a nerve block (called Quadro Iliac Plane Block) given during kidney stone surgery to see if it helps control pain after the procedure. If you are having this type of surgery and are generally healthy, you may be able to join.
Sivas, SivasAges 18–65
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Common questions
- Are there clinical trials for postoperative pain?
- Yes. Clin2 currently lists 538 recruiting postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain, Acute
- Postoperative Pain Management
- Chronic Postoperative Pain
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.