Clinical trials
Postoperative Pain clinical trials
Below are recruiting postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 561 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07743606Enrolling by invitationPhase 3
Pain medicine after lower back fusion surgery
This study tests whether taking a nonsteroidal anti-inflammatory drug (NSAID) like ibuprofen after lumbar spine fusion surgery is safe and helps with pain without affecting bone healing. It may offer an alternative to stronger pain medicines.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05906134RecruitingPhase 1/Phase 2
Pain control plan after minimally invasive esophagus surgery
This trial tests a pain-control method (using an epidural/nerve pain-block through the back, called neuraxial anesthesia) for people having minimally invasive esophagus removal surgery. It may help reduce pain after surgery and improve comfort during recovery.
Seattle, WashingtonAges 18 years+ - NCT06271174RecruitingPhase 3
Preventing long-term pain after child surgery
This study tests whether a pain block (medicine injected near nerves) can prevent long-term pain after a child's bone or joint surgery. It aims to help children have less pain months later.
NantesAges 5 years–15.3 years - NCT06918470Recruiting
Do noise cancelling headphones help with pain after surgery?
This study tests whether wearing noise cancelling headphones after gynecologic laparoscopy can reduce pain. If you are a woman having this surgery, you may be able to participate.
Wuhan, HubeiAges 18–55 - NCT07023497Recruiting
Finding the best dose of spinal morphine for C-section pain relief
This study tests different doses of morphine given through a spinal injection during a planned C-section to find the best balance of pain relief and side effects. It may help women have better pain control after surgery.
Ioannina, EpirusAges 18–50 - NCT07159334Recruiting
Lidocaine vs Nitroglycerin for Pain After Hemorrhoid Surgery
This study compares a lidocaine ointment versus a nitroglycerin (GTN) ointment for pain relief after hemorrhoid removal surgery. It aims to see which works better for patients with advanced hemorrhoids.
Lahore, Punjab ProvinceAges 18–60 - NCT07198412Recruiting
Study on sedation's effect on back pain after spinal anesthesia
This study looks at whether giving sedation (medicine to help you relax) during spinal anesthesia can reduce back pain after surgery. It's for people having certain types of surgery on their lower abdomen or legs.
Banhā, Qalyubia GovernorateAges 18–65 - NCT07435909Recruiting
Bupivacaine for pain after laparoscopic hysterectomy
This trial tests if injecting a numbing medicine called bupivacaine into the abdomen during surgery can reduce pain after a laparoscopic hysterectomy (uterus removal through small cuts). It may help you recover with less discomfort.
Istanbul, GaziosmanpaşaAges 35–75 - NCT07440940Recruiting
Timing of pain blocks for gallbladder surgery recovery
This study is testing whether giving a numbing block (under the ribs and around the belly button) at a certain time before gallbladder removal surgery helps reduce pain after the operation. It aims to find the best timing for these pain blocks to improve your recovery.
SeoulAges 18–80 - NCT07640646Recruiting
Heart Surgery and Long-Term Pain: A Patient Survey
This study asks patients who had heart surgery in the past year about any ongoing pain or discomfort in the surgical area. The goal is to understand how common long-term pain is after heart surgery and how it affects daily life.
Leuven, Vlaams BrabantAges 18 years+ - NCT06716359Enrolling by invitation
Comparing two pain medicines after C-section
This trial compares two pain relievers, hydromorphone and nalbuphine, given through a patient-controlled pump after cesarean section. It aims to find which provides better pain control with fewer side effects.
Wuhan, HubeiAges 20–50 - NCT07048522Recruiting
Nimodipine before bowel cancer surgery
This trial tests if giving nimodipine before and after surgery for bowel cancer can help improve recovery and reduce pain. It may be a good fit if you meet the age and health requirements.
Pátrai, AchaeaAges 18–75 - NCT07446868Recruiting
Comparing two nerve blocks for pain after mastectomy
This trial compares two nerve-block techniques (SPSIP and ESPB) to see which one provides better pain relief after breast cancer surgery. The goal is to reduce pain and improve recovery after a modified radical mastectomy.
Cairo, Cairo GovernorateAges 18–65 - NCT07436806Recruiting
Comparing nerve blocks for pain after chest surgery
This trial compares two types of nerve blocks to see which one better prevents long-term pain after video-assisted chest surgery. It may help find a way to reduce chronic pain after your procedure.
Istanbul, BagcilarAges 18–75 - NCT07186426RecruitingPhase 3
Testing HSK21542 for pain after hip replacement surgery
This trial tests a new pain medicine called HSK21542 for people who have hip replacement surgery under general anesthesia. It aims to see if the drug can safely reduce moderate to severe pain after surgery.
Beijing, Beijing MunicipalityAges 18–74 - NCT05009771Recruiting
Testing a pain-control method after C-section
This study looks at how to better manage pain after a C-section using spinal anesthesia and either a patient-controlled IV pain pump or a specific pain medicine (naldebaein). You may be able to join if you’re scheduled for a C-section at 37–40 weeks and can take the usual pain medicines.
New Taipei City, TaiwanAges 20–40 - NCT06907810Recruiting
Study of fat molecules in long-term breast surgery pain
This trial looks at how certain natural fat molecules in your body might relate to long-term pain after breast cancer surgery. It could help doctors better understand and treat chronic pain in the future.
Brussels, Brussels CapitalAges 18 years+ - NCT06957158Recruiting
How calcium levels affect pain after abdominal surgery
This study looks at whether calcium levels in your blood can affect how much pain you feel after abdominal surgery. It may help doctors manage pain better after surgery in the future.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT07377370Recruiting
Pain after gum graft surgery study
This study looks at factors that affect pain after a gum graft procedure. If you need gum surgery to cover exposed tooth roots or add gum tissue, you may be able to join.
Barcelona, Sant Cugat Del VallesAges 18 years+ - NCT07396545Recruiting
Comparing two types of nerve blocks for pain after stomach cancer surgery
This trial looks at two different pain-blocking injections (nerve blocks) to see which one works better for pain after keyhole stomach cancer surgery. If you are having this type of surgery, joining could help us learn which block gives you better pain relief.
Yinchuan, NingxiaAges 18 years+ - NCT07483190Recruiting
Nerve block for pain after laparoscopic hysterectomy
This study tests a nerve block called M-TAPA to reduce pain after laparoscopic hysterectomy. It may help you need less pain medicine and recover more comfortably.
IstanbulAges 18–70 - NCT07496086Recruiting
Comparing two nerve blocks for stomach surgery pain
This trial compares two types of nerve blocks to see which one reduces pain better after laparoscopic stomach cancer surgery. If you qualify, you'll help doctors find the best way to manage pain with fewer side effects.
YinchuanAges 18 years+ - NCT06774274RecruitingPhase 4
Ketamine for pain after major orthopedic surgery: drip vs. pump
This study tests two ways of giving a medicine called ketamine to control pain after major bone or joint surgery. One method is a steady infusion (drip) through a vein, and the other is a patient-controlled pump (PCA) that lets you press a button for more medicine when you need it.
Medellín, AntioquiaAges 18 years+ - NCT07285083Recruiting
Pain relief after abdominal surgery: comparing two numbing medicines
This study compares two numbing medicines (bupivacaine alone vs. bupivacaine plus dexmedetomidine) to see which provides better pain relief after abdominal surgery. If you are having a planned abdominal operation, this trial may help improve your recovery comfort.
Rahim Yar Khan, Punjab ProvinceAges 21–45
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Common questions
- Are there clinical trials for postoperative pain?
- Yes. Clin2 currently lists 561 recruiting postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain, Acute
- Postoperative Pain Management
- Chronic Postoperative Pain
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.