Clinical trials
Preoperative clinical trials
Below are recruiting preoperative clinical trials, each written for real people, not researchers. We’re tracking 376 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07244575Recruiting
Metformin and nausea after general anesthesia study
This study looks at whether the diabetes medicine metformin, taken before surgery, affects the risk of nausea and vomiting after general anesthesia. If you take metformin and are having planned surgery, this trial may help understand its effects.
Guangzhou, GuangdongAges 18 years+ - NCT07233538Recruiting
Numbing injection before nose surgery for better pain relief
This study tests a numbing injection in the cheek area before septorhinoplasty to see if it improves pain control and reduces the need for strong IV pain medicine. It may help you have a smoother recovery with less discomfort.
Ankara, YenimahalleAges 18–65 - NCT07221786Recruiting
Opioid reduction before spine surgery
This trial tests whether slowly reducing opioid pain medications before spine surgery can lead to a better recovery afterward. It is for adults already taking daily opioids who have major spine surgery planned at least a month away.
Philadephia, PennsylvaniaAges 18 years+ - NCT06505577Recruiting
Comparing Tumor Size Before and After Breast Cancer Surgery
This study compares the size of a breast tumor measured before surgery (using imaging tests like mammogram or ultrasound) with the actual size found after the tumor is removed. It helps understand how accurate preoperative measurements are for patients having breast cancer surgery.
IncheonAges 19 years+ - NCT06912815Recruiting
Ustekinumab and nutrition before Crohn's surgery
This trial tests if combining a drug called ustekinumab with a special liquid diet (semi-exclusive enteral nutrition) is as effective as using only the liquid diet to improve outcomes before Crohn's surgery.
Guangzhou, GuangdongAges 18–65 - NCT06917300Recruiting
Virtual reality to reduce pain and anxiety before spine surgery
This trial tests if using virtual reality before surgery can help reduce pain and anxiety in people having elective spine surgery. If you're scheduled for spine surgery and speak Polish, you may be able to participate.
Lodz, Łódź VoivodeshipAges 25–70 - NCT07220382RecruitingPhase 4
Botox injections before large hernia surgery
This trial tests if getting Botox shots in the belly muscles before hernia surgery makes the repair easier and more successful. It is for adults who need a planned, open surgery for a large ventral hernia.
Cleveland, OhioAges 18 years+ - NCT05197972Recruiting
Hypnosis and heart-breathing training to reduce cancer surgery anxiety
This study tests whether guided “heart-breathing” and hypnosis (through an app) can lower anxiety before cancer surgery. It may help you feel calmer in the days leading up to the operation.
Montpellier, HéraultAges 18 years+ - NCT07193524Recruiting
Study of a new tool to analyze fractures before surgery
This trial is testing a new computer tool that helps doctors plan surgery for a broken leg. It looks at pictures of the break to see if it can make surgery better or easier.
Boston, MassachusettsAges 18 years+ - NCT06710353Recruiting
Albumin before heart surgery for kids with low albumin
This study tests whether giving albumin (a protein in the blood) before heart surgery helps protect the kidneys of young children with low albumin levels. It may help reduce the risk of kidney injury after surgery.
Seoul, SeoulAges Up to 7 years - NCT07192978Recruiting
Does activity before surgery affect recovery after hernia repair?
This study looks at whether how active you are before hernia surgery can affect your recovery. It may help doctors give better advice to future patients.
StrasbourgAges 18 years+ - NCT07180823Recruiting
Lung nodule tagging before surgery using a navigation system
This trial uses a special navigation system to place tiny markers next to lung nodules before surgery. This helps surgeons find and remove the nodule more precisely.
Bologna, BolognaAges 18 years+ - NCT07170345Recruiting
AI to detect hidden spread in liver cancer from scans
This trial uses a computer program to help doctors find signs of microscopic tumor spread in blood vessels (microvascular invasion) from liver cancer images. It aims to improve treatment planning for patients who are having surgery.
Fuzhou, FujianAges 18–18 - NCT07165483Recruiting
Timing of dexmedetomidine for surgery stress response
This trial tests whether giving a single dose of dexmedetomidine (a medicine that helps calm the body's stress response) before surgery can reduce the stress on your heart and blood pressure when a breathing tube is placed. It may help you recover more smoothly.
Tanta, El-GharbiaAges 18–65 - NCT07172386RecruitingPhase 2
Pre-surgery treatment for advanced kidney cancer
This trial tests if a combination of targeted embolization, immunotherapy (Toripalimab), and a targeted therapy pill (Axitinib) can shrink advanced kidney cancer before surgery. It is for patients whose cancer has spread to nearby tissues or lymph nodes, or has limited spread elsewhere that can be removed.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07171203RecruitingPhase 1
Imatinib and fampridine before surgery for KIT-mutant GIST
This trial tests whether combining two oral medications, imatinib and fampridine, before surgery can shrink GIST tumors that have a specific KIT gene mutation. The goal is to improve surgical outcomes and potentially reduce the risk of the tumor coming back.
La Jolla, CaliforniaAges 18 years+ - NCT07159451RecruitingPhase 2
Elacestrant for premenopausal women with early breast cancer
This trial tests a new hormone therapy pill, elacestrant, given alone or with another drug to suppress ovarian function before surgery. It's for premenopausal women with early-stage, hormone receptor-positive, HER2-negative breast cancer to see if it can shrink the tumor.
VillejuifAges 18 years+ - NCT07148063Recruiting
Blood tests to predict nausea after testicle surgery in children
This trial looks at whether certain blood tests can predict nausea and vomiting after surgery to fix undescended testicles in young children. It involves taking a blood sample before the procedure to check for markers of inflammation.
Altındağ, AnkaraAges 1–8 - NCT04261244RecruitingPhase 3
Neoadjuvant radiation study for one-sided breast cancer
This Phase 3 study tests a specific plan that combines chemotherapy (and sometimes targeted medicines) with radiation before surgery for one breast. It may help shrink breast cancer and improve treatment timing, based on how well tumors respond.
AhausAges 18 years+ - NCT07125859Recruiting
Nutrition support before surgery study
This study looks at how common malnutrition is in adults getting ready for surgery and whether nutrition counseling helps improve their nutritional health before the operation.
BangkokAges 18 years+ - NCT07104370Recruiting
Comparing freeze-dried donor bone vs. your own bone for jaw grafting
This trial compares two types of bone graft materials for rebuilding the jawbone so you can later get dental implants. One is a freeze-dried bone from a donor (allograft), and the other is a small piece of your own bone (autograft).
Budapest, HungaryAges 18 years+ - NCT07101250RecruitingPhase 4
Study of acetazolamide before laparoscopic hysterectomy
This trial tests a medication called acetazolamide given before surgery to see if it can help prevent shoulder pain after a laparoscopic hysterectomy. If you are a woman scheduled for this type of hysterectomy, you may be able to join.
Greenville, South CarolinaAges 21–65 - NCT06219252Recruiting
Comparing lens power methods during cataract surgery
This study compares two ways to choose the right lens power during cataract surgery: one uses a special measurement during surgery, the other uses standard pre-surgery measurements. The goal is to see which method gives you better vision after surgery.
Mexico City, CuauhtemocAges 40 years+ - NCT06970431Recruiting
Anxiety and pain relief during C-section
This trial tests a way to reduce anxiety and pain before and during a C-section. It may help pregnant women feel calmer and more comfortable.
Wuhan, HubeiAges 18–40
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Common questions
- Are there clinical trials for preoperative?
- Yes. Clin2 currently lists 376 recruiting preoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a preoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a preoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.