Clinical trials
Preoperative clinical trials
Below are recruiting preoperative clinical trials, each written for real people, not researchers. We’re tracking 376 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07357571Recruiting
Can ultrasound help predict lymph node spread in early thyroid cancer?
This trial uses contrast-enhanced ultrasound before surgery to see if it can predict whether cancer has spread to lymph nodes in patients with early-stage papillary thyroid cancer. The goal is to improve treatment planning without unnecessary surgery.
Guangdong, GuangzhouAges Any age - NCT07350928RecruitingPhase 3
Nasal spray before breast-saving surgery for calm wakefulness
This trial tests a nasal spray (dexmedetomidine) given before breast-conserving surgery to help you stay calm and comfortable while awake during the procedure. It aims to improve your recovery and waking experience after surgery.
TianjinAges 20–70 - NCT07339202Recruiting
Timing of dialysis before surgery for kidney failure
This study looks at the best timing for dialysis before planned surgery in people with kidney failure. It aims to find out if changing when you have dialysis can improve recovery and reduce complications.
Stanford, CaliforniaAges 18 years+ - NCT07324967Recruiting
Counseling for transmasculine patients before gender-affirming surgery
This study tests a counseling approach to help transmasculine and non-binary people prepare for a hysterectomy (removal of the uterus) as part of gender-affirming care. The goal is to see if this counseling improves knowledge and decision-making.
Minneapolis, MinnesotaAges 18–65 - NCT07322497Recruiting
Phone app vs. supervised exercise before ACL surgery
This study compares two ways to exercise before ACL surgery: using a video app on your phone versus doing exercises with a physical therapist. The goal is to see which approach helps you recover better.
Istanbul, KartalAges 18–45 - NCT07324057Recruiting
Medication before surgery to reduce autism-related anxiety in children
This trial tests whether a nose spray given before anesthesia can help children with autism feel calmer and have fewer behavior problems after surgery. It compares two medications, dexmedetomidine and esketamine, to see if they reduce negative post-surgery changes.
Nanjing, JiangsuAges 2–12 - NCT07323940Recruiting
Can brain waves during surgery predict delirium after?
This study looks at whether brain activity patterns during your surgery can predict confusion or delirium after the operation. It may help doctors better prevent postoperative confusion in older adults.
HaikouAges 65 years+ - NCT06698757RecruitingPhase 2
Testing different cycles of sintilimab before surgery for colorectal cancer
This trial tests how many cycles of the immunotherapy drug sintilimab given before surgery help treat colorectal cancer that is mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H). It is for locally advanced cancer that has not spread to other parts of the body.
Zheng'zhou, HenanAges 18–75 - NCT06780735Recruiting
Breast-sparing surgery using a special dye after chemo
This trial tests a technique where doctors use a special dye (ICG) to guide breast-conserving surgery in patients whose tumors have shrunk enough after chemotherapy. The goal is to remove only the cancer while saving as much healthy breast tissue as possible.
Goyang-si, Gyeonggi-doAges 18 years+ - NCT07315308Recruiting
Nerve block before heart surgery and painkiller use
This study tests whether a numbing injection in the chest before heart surgery can reduce the amount of pain medicine needed during the operation. It may help you manage pain better and recover more comfortably.
Gaziantep, SahinbeyAges 18–65 - NCT07304115Recruiting
Noise from mechanical heart valve and quality of life
This study looks at how the noise from a mechanical heart valve affects your quality of life after surgery. You will be asked about your memories of the information you received before surgery and how you feel now.
ParisAges 18 years+ - NCT07294690Recruiting
Virtual reality training before colorectal cancer surgery
This study uses virtual reality training before colorectal cancer surgery to see if it helps reduce anxiety and prepare you better for the procedure, leading to a smoother recovery.
IstanbulAges 18–70 - NCT07287605Recruiting
Virtual reality for mood during focused ultrasound for essential tremor
This study tests if using virtual reality can improve your mood while you undergo a focused ultrasound procedure for essential tremor. If you are already scheduled for this treatment, you may be able to join.
North York, OntarioAges 18 years+ - NCT06866457Recruiting
Audio hypnosis to reduce MRI anxiety in kids
This trial tests if listening to an audio hypnosis recording can help children and teens feel less anxious during an MRI scan. If it works, it could offer a drug-free way to help young patients stay calm during the exam.
EssenAges 6–14 - NCT07278661RecruitingPhase 2
Pre-surgery romiplostim for patients with low platelets having heart surgery
This trial tests if giving romiplostim before heart surgery can safely increase low platelet counts. It may help patients with low platelets avoid bleeding complications during and after surgery.
AngersAges 18 years+ - NCT07276880RecruitingPhase 2
Chemo, immunotherapy, and radiation for lymph node-positive triple-negative breast cancer
This trial tests a combination of chemotherapy, the immunotherapy drug pembrolizumab, and low or high-dose radiation before surgery for people with triple-negative breast cancer that has spread to the lymph nodes. The goal is to see if this approach can improve treatment outcomes.
Chapel Hill, North CarolinaAges 18 years+ - NCT07270445Recruiting
VR for anxiety before surgery
This study tests whether using virtual reality (VR) before surgery can help lower anxiety. If you are an adult having planned surgery and are comfortable using a VR headset, you may be able to join.
BonnAges 18 years+ - NCT06894797Recruiting
Chemo and radiation before and after surgery for rectal cancer
This study tests a sequence of chemotherapy and radiation before and after surgery for rectal cancer. It compares giving more chemo between the end of radiation and surgery (consolidation) versus giving some chemo before radiation starts (induction). The goal is to see which order works better.
BeijingAges 18–75 - NCT07265544Recruiting
Liver disease study using advanced tissue analysis
This study uses advanced techniques to analyze liver tissue samples from people with various liver conditions. It aims to better understand how liver diseases develop and progress, which may help improve future treatments.
Guangzhou, GuangdongAges Any age - NCT07268846Recruiting
Prebiotic supplement before colorectal cancer surgery
This trial tests if taking a postbiotic supplement before surgery for colorectal cancer can improve recovery. It may help patients with adenocarcinoma of the large intestine prepare for their operation.
São Paulo, São PauloAges 18 years+ - NCT07255729Recruiting
Blood Test for Colon Cancer Staging
This study looks at a new blood test that may help doctors better understand how far colon cancer has spread. By testing a sample of your blood (taken before surgery), researchers hope to find patterns that predict the stage of cancer and help guide treatment decisions.
Duarte, CaliforniaAges 18 years+ - NCT06061874Recruiting
New PET scan for spotting cancer spread in the abdomen
This trial tests a new type of PET scan (Ga68-FAPI-46) to better see if cancer from the colon, rectum, or ovary has spread to the lining of the belly. If you are already scheduled for surgery to remove these cancer spots, this scan may help your doctors plan a more complete operation.
BrusselsAges 18 years+ - NCT06130956Recruiting
Vegan diet before knee replacement surgery study
This study compares a 2-week vegan diet to a regular diet before knee replacement surgery. It looks at how the diet affects protein turnover in the knee joint.
ArnhemAges 60–80 - NCT07244575Recruiting
Metformin and nausea after general anesthesia study
This study looks at whether the diabetes medicine metformin, taken before surgery, affects the risk of nausea and vomiting after general anesthesia. If you take metformin and are having planned surgery, this trial may help understand its effects.
Guangzhou, GuangdongAges 18 years+
Hear when a new Preoperative trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for preoperative?
- Yes. Clin2 currently lists 376 recruiting preoperative studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a preoperative trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a preoperative trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.