Clinical trials
Prostatectomy clinical trials
Below are recruiting prostatectomy clinical trials, each written for real people, not researchers. We’re tracking 139 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06085664RecruitingPhase 1/Phase 2
Immunotherapy before prostate cancer surgery
This trial tests a new immunotherapy drug (REGN5678) given before surgery to men with high-risk prostate cancer that hasn't spread. The goal is to see if the drug can shrink or control the cancer before the prostate is removed.
Houston, TexasAges 18 years+ - NCT07426861Recruiting
Nurse-led education before prostate surgery to reduce incontinence
This study tests whether a nurse-led education program and direct referral to a physiotherapist before prostate removal surgery can help reduce urine leakage (incontinence) after the operation. It may help you recover better bladder control.
Beaumont, DublinAges 18 years+ - NCT07427043RecruitingPhase 3
Opioid-free pain plan for robotic prostate surgery
This trial tests a pain management strategy that avoids opioids during and after robotic prostate surgery. It aims to reduce opioid use and side effects while keeping you comfortable.
Boston, MassachusettsAges 45 years+ - NCT07477626RecruitingPhase 3
Radiation therapy after prostate surgery for advanced prostate cancer
This study tests whether radiation therapy to the pelvis after prostate removal helps men whose cancer was found in nearby lymph nodes. The goal is to prevent cancer from coming back and improve survival.
Dongguan, GuangdongAges 18 years+ - NCT07534696Enrolling by invitation
Pelvic floor stimulation for urinary leakage after prostate surgery
This study tests a non-invasive (no surgery or needles) electrical stimulation device to help men regain bladder control after prostate removal surgery. The device uses gentle electrical pulses on the pelvic floor muscles to retrain them and reduce urine leakage.
Santa Monica, CaliforniaAges 18 years+ - NCT07439913Enrolling by invitation
Predicting cancer return and bladder control after robot prostate surgery
This study looks at factors that can predict whether prostate cancer will come back in the 10 years after robot-assisted prostate removal surgery, and how well bladder control (urinary continence) recovers. It helps doctors understand which patients might do better long-term.
Banská BystricaAges Any age - NCT07205783Enrolling by invitation
Comparing surgery and radiation for early prostate cancer
This trial compares two standard treatments for prostate cancer that hasn't spread: surgery to remove the prostate (radical prostatectomy) and radiation therapy (curative radiotherapy). It looks back at past patients to see which treatment worked better.
SohagAges 40 years+ - NCT04167969RecruitingTeam says not enrollingPhase 1
Nanoparticles to help guide prostate cancer surgery
This Phase 1 study tests nanoparticles (tiny particles) that are meant to help surgeons better find and remove prostate cancer tissue during surgery. You may be offered standard prostate surgery plus imaging with a study tracer to guide the operation.
New York, New YorkAges 18 years+ - NCT06511141Recruiting
Nerve stimulation for men with overactive bladder
This study tests a nerve stimulation device placed near the tailbone to help men with overactive bladder symptoms. If you have bothersome urinary urgency or frequency, this treatment may offer relief without drugs.
Birmingham, AlabamaAges 18 years+ - NCT07455903RecruitingPhase 2
Hormone therapy before surgery for high-risk prostate cancer
This trial tests whether giving hormone therapy (androgen deprivation therapy) before surgery can improve outcomes for men with high-risk prostate cancer. You will receive a special PSMA PET/CT scan to see how the cancer responds.
Miami, FloridaAges 18 years+ - NCT06966778Recruiting
Oxybutynin to help bladder control after prostate surgery
This trial tests if the medicine Oxybutynin ER (a drug that helps relax the bladder) can help you regain bladder control sooner after robotic prostate surgery. Participants will be randomly assigned to receive either the drug or a placebo for a few weeks after surgery.
TaipeiAges 18 years+ - NCT06834321RecruitingPhase 2
Homoharringtonine with hormone therapy before prostate surgery
This trial tests a new combination of a chemotherapy drug (homoharringtonine) and hormone therapy (androgen deprivation) given before surgery to shrink prostate cancer that has spread a little or is advanced. The goal is to see if this approach can help control the cancer better before the prostate is removed.
Nanjing, JiangsuAges 18–85 - NCT05109208Recruiting
Ultrasound check for erection recovery after prostate surgery
This study looks at whether ultrasound imaging can help understand and improve erectile function after prostate removal surgery that aims to protect the nerves. If you’re interested in keeping or improving erections, your ultrasound results may be used to guide follow-up care.
Rochester, MinnesotaAges 40 years+ - NCT05406999RecruitingPhase 2
Intense hormone treatment before prostate surgery for high-risk cancer
This Phase 2 trial studies giving strong hormone-based treatment before prostate surgery to shrink and control high-risk, locally advanced prostate cancer. It may help improve surgical success and reduce cancer spread risk, but it requires careful health checks and prior-treatment limits.
Nanjing, JiangsuAges 18–80 - NCT06798558RecruitingPhase 2
Lu-PSMA before prostate surgery for high-risk cancer
This trial tests a treatment called Lu-177-PSMA-617 given before surgery for high-risk prostate cancer that has spread only to nearby lymph nodes. It aims to see if this approach helps control the cancer before the prostate is removed.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06022822RecruitingPhase 2
Urolithin A supplement before prostate cancer surgery
This trial tests whether taking a supplement called urolithin A for a few weeks before prostate removal surgery can help. The supplement comes from pomegranates and may slow cancer growth. You may qualify if you have prostate cancer, are planning surgery within 3-6 weeks, and have not had prior treatment like hormone therapy.
Los Angeles, CaliforniaAges 18 years+ - NCT07610824Recruiting
Lung Pressure and Recovery After Robot-Assisted Prostate Surgery
This study measures breathing pressure during robot-assisted prostate removal surgery and checks lung function after surgery using ultrasound. It aims to understand how surgery affects your lungs and recovery.
Ankara, AnkaraAges 18–80 - NCT07451106Recruiting
Wearable bladder sensor for pelvic health therapy
This trial tests whether a wearable sensor for the bladder can help guide pelvic health physical therapy. It is designed for people who are already referred to pelvic PT, including postpartum women and men who have had prostate surgery.
San Francisco, CaliforniaAges 18 years+ - NCT06888102RecruitingEarly Phase 1
Epigenetic therapy before prostate surgery
This trial tests a short course of 'epigenetic therapy' (drugs that change how genes work) given before prostate removal surgery. The goal is to see if it can improve treatment effects and help shrink or control the tumor.
Los Angeles, CaliforniaAges 18 years+ - NCT06758882RecruitingPhase 2
Surgery with or without apalutamide for high-risk prostate cancer that has spread a little
This trial tests whether adding the drug apalutamide before and after surgery helps men with high-risk prostate cancer that has spread to a few spots (seen on a special PET scan). You would also receive standard hormone therapy.
Torino, ToAges 18–80 - NCT06968494Recruiting
Implantable device to preserve erections after prostate surgery
This trial tests a new implantable device designed to help men keep their erections after nerve-sparing prostate surgery. If you are having surgery for early-stage prostate cancer and have good erectile function now, this device might help you maintain it.
Baltimore, MarylandAges 30–75 - NCT07208240RecruitingPhase 1/Phase 2
PSMA-targeted radiation before prostate removal for advanced cancer
This trial tests giving a radioactive drug (PSMA-targeted) before surgery for prostate cancer that has spread locally but not to other parts of the body. The goal is to see if it helps lower the risk of the cancer coming back.
Petah TikvaAges 18 years+ - NCT06861192RecruitingPhase 2/Phase 3
Fasudil and immunotherapy with hormone therapy for prostate cancer
This trial tests a new combination of drugs (Fasudil, a PD1 inhibitor, and hormone therapy) before prostate cancer surgery to see if it works better than standard treatment. It's for patients with early metastatic or locally advanced prostate cancer who haven't had any prior treatment.
Nanjing, JiangsuAges 18–85 - NCT05650866Recruiting
Testing an implanted device to help erections after prostate surgery
This trial checks whether a new implanted device is safe and tolerable to help improve erections after nerve-sparing prostate surgery. It may help men who want to reduce erectile side effects from prostatectomy, but it also excludes several groups who have erection-related problems or nerve issues.
Fitzroy, VictoriaAges 30–70
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Common questions
- Are there clinical trials for prostatectomy?
- Yes. Clin2 currently lists 139 recruiting prostatectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a prostatectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a prostatectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.