Clinical trials
Radiation Therapy clinical trials
Below are recruiting radiation therapy clinical trials, each written for real people, not researchers. We’re tracking 675 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07101432RecruitingPhase 1
Radiation plus engineered NK cells for advanced head and neck cancer
This early-phase trial tests a new type of immune cell therapy combined with radiation for advanced head and neck cancer. The cells are engineered to target the TROP2 marker on cancer cells and are given after a short course of radiation to help them work better.
Houston, TexasAges 18 years+ - NCT06971211RecruitingPhase 2
Radiation and drug combo for advanced prostate cancer
This trial combines radiation therapy with two drugs (fluzopanib and abiraterone acetate) to treat men with metastatic castration-resistant prostate cancer that hasn't been treated yet. The goal is to see if this triple approach helps slow the cancer's growth.
Shenyang, LiaoningAges 18 years+ - NCT05915442RecruitingPhase 2
Adenosine blocker plus immunotherapy for limited prostate spread
This Phase 2 study tests a medicine that affects “adenosine” signaling along with an immune checkpoint inhibitor (immunotherapy) in men with hormone-sensitive prostate cancer that has spread in only a small, limited way. It aims to stop or slow that limited spread by helping the immune system work better.
New York, New YorkAges 18–99 - NCT05192876Recruiting
Review of outcomes and side effects during radiation treatment
This study collects information about results and side effects from people receiving radiation therapy at a specific hospital. It may help improve how radiation treatment is planned and monitored in the future.
Winterthur, Canton of ZurichAges 16–105 - NCT05406063Recruiting
Focused radiation for bone metastases causing pain
This trial studies a precise type of radiation given in multiple small sessions to treat bone metastases that are causing pain. It may help shrink or control the spots in the bone while aiming to reduce side effects by targeting the area closely.
Winterthur, Canton of ZurichAges 18 years+ - NCT06984250Recruiting
Shorter radiation with extra focus on tumor site for breast cancer
This trial tests a shorter course of radiation therapy that includes an extra dose to the tumor site for women with early-stage breast cancer. It aims to make treatment more convenient and effective after breast-conserving surgery.
Taipei, TaiwanAges 20–85 - NCT07058948RecruitingPhase 2
Combining special radiation with immunotherapy for advanced cancer
This trial tests a new type of radiation combined with immunotherapy for people with advanced solid tumors that are no longer responding to standard treatments or cannot tolerate them. The goal is to see if this combination can help control the disease.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07046078RecruitingPhase 2
Chemo, radiation, and donor transplant for older adults with high-risk AML
This trial tests a combination of chemotherapy (FLAG-Ida) followed by low-dose total body radiation and a stem cell transplant from a donor. It is for people age 60 and older with newly diagnosed high-risk blood cancers, aiming to improve outcomes with a less intense transplant preparative regimen.
Seattle, WashingtonAges 18 years+ - NCT07049848RecruitingPhase 2
Study of atezolizumab with chemo and radiation for high-risk sarcoma
This trial tests a combination of immunotherapy (atezolizumab), chemotherapy (doxorubicin), and radiation before and after surgery for people with high-risk soft tissue sarcoma in the arm, leg, or trunk. The goal is to see if this approach can improve outcomes.
Houston, TexasAges 18 years+ - NCT07047495Recruiting
Personalized radiation therapy for early breast cancer
This trial is testing a way to personalize radiation therapy for people with early-stage breast cancer. It may help make treatment more precise and reduce side effects.
Milan, ItalyAges 18 years+ - NCT06991465RecruitingPhase 2
Organ preservation trial for rectal cancer using shorter radiation
This trial tests a shorter course of radiation to the pelvis to treat rectal cancer, with the goal of avoiding surgery and preserving the rectum. It may be an option for people with advanced rectal cancer that has not spread to other organs.
Montreal, QuebecAges 18–90 - NCT07043608RecruitingPhase 2
Zanzalintinib for kidney cancer that spread to bone
This trial tests a new drug called zanzalintinib for people with advanced clear cell kidney cancer that has spread to the bones (at least 3 spots). The study wants to see if this drug can help slow down or shrink the cancer. It's for patients who have already had some prior treatments.
San Francisco, CaliforniaAges 18 years+ - NCT07039162RecruitingPhase 2
Tislelizumab with chemo and radiation before surgery for advanced esophageal cancer
This trial tests a combination of an immunotherapy drug (tislelizumab) with chemotherapy and radiation, followed by surgery, for people with advanced esophageal cancer that cannot be removed right away. It aims to see if this approach can help shrink the tumor enough to allow surgery.
Kaohsiung CityAges 20 years+ - NCT05071105Recruiting
Short-course radiation for early breast cancer in older women
This study looks at a brief type of radiation called SBRT given soon after starting hormone therapy for certain early breast cancers in women age 75 and older. It may help treat the cancer locally while aiming to be easier to receive than longer radiation schedules.
Rome, RomeAges 75 years+ - NCT07014618Recruiting
Study to help breast and prostate cancer patients finish radiation therapy
This study tests whether a navigator program helps people from certain backgrounds complete their radiation therapy. If you have breast or prostate cancer and are scheduled for radiation, you may be able to join.
Oklahoma City, OklahomaAges 18 years+ - NCT06997094RecruitingPhase 1
Decitabine plus standard therapy for HPV-negative head and neck cancer
This trial tests whether adding the drug decitabine to standard treatment (surgery and possibly radiation) can help people with a type of head and neck cancer not caused by HPV. You would receive decitabine before surgery, and then continue with standard care after.
Jacksonville, FloridaAges 18 years+ - NCT06990061Recruiting
Radiation therapy for BCG-resistant bladder CIS
This trial tests radiotherapy (high-energy X-rays) for a specific type of early-stage bladder cancer (CIS) that hasn't gone away after BCG treatment. It's for people who can't or choose not to have bladder removal surgery.
Anderlecht, Brussels CapitalAges 18 years+ - NCT06990542RecruitingPhase 2
Focused radiation therapy for intermediate and high-risk prostate cancer
This trial tests a more precise radiation therapy that targets tumors seen on MRI or special scans, aiming to treat prostate cancer while reducing side effects. It is for men who have not had prostate surgery or previous radiation to the area.
La Jolla, CaliforniaAges 18 years+ - NCT06984861RecruitingPhase 2
Reduced radiation with chemo for HPV-related throat cancer
This trial tests if giving less radiation along with chemotherapy is safe and effective for people with HPV-positive throat cancer. It aims to reduce side effects while still controlling the cancer.
Basking Ridge, New JerseyAges 18 years+ - NCT06992427RecruitingPhase 3
Gabapentin to prevent opioid use for mouth pain during cancer treatment
This trial tests if taking gabapentin during chemoradiation for head and neck cancer can reduce the need for strong painkillers like opioids. It may help manage mouth pain caused by treatment.
Gilbert, ArizonaAges 18 years+ - NCT06969820Recruiting
Low-dose radiation for heel pain with plantar fasciitis
This study tests whether low-dose radiation therapy (LDRT) can help people with long-term heel pain from plantar fasciitis and a heel spur. It uses imaging and checkups to measure how well the treatment works.
Erlangen, BavariaAges 40 years+ - NCT06961955RecruitingPhase 2
Shorter versus longer whole breast radiation for early-stage breast cancer
This trial compares a 5-day course of whole breast radiation plus a boost to the standard 9-day course for people with early-stage breast cancer who have certain risk factors, such as high-grade tumors or younger age. The goal is to see if the shorter treatment is just as safe and effective.
Salt Lake City, UtahAges 18 years+ - NCT05253495RecruitingPhase 2
Targeted immunotherapy added to chemotherapy and radiation for lymphoma
This Phase 2 trial tests whether adding targeted immunotherapy to standard chemotherapy and radiation can improve outcomes in children with certain types of lymphoma. It may help the immune system work better against cancer.
Birmingham, AlabamaAges 3–39 - NCT06936748RecruitingPhase 2
Radiation plus immunotherapy for large relapsed solid tumors
This trial tests a new combination of radiation therapy and two immunotherapy drugs (Iparomlimab and Tuvonralimab) for people whose solid tumors have returned or spread and are too large for standard surgery. The goal is to shrink the tumor and control the cancer.
Nanchang, JiangxiAges 18–75
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Common questions
- Are there clinical trials for radiation therapy?
- Yes. Clin2 currently lists 675 recruiting radiation therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiation therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiation therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.