Clinical trials
Stereotactic Body Radiation Therapy (SBRT) clinical trials
Below are recruiting stereotactic body radiation therapy (sbrt) clinical trials, each written for real people, not researchers. We’re tracking 106 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03253536Recruiting
Quality of life study after precise liver radiation
This study follows people with liver cancer (hepatocellular carcinoma) to see how their quality of life changes after a focused form of radiation called stereotactic ablative radiation therapy. It does not appear to test a new drug—rather, it measures patient-reported well-being after treatment.
Munich, BavariaAges 18 years+ - NCT04985032Recruiting
Radiation after lumpectomy for selected breast tumors
This trial tests a shorter, focused type of radiation (APBI using SBRT) after lumpectomy for certain early breast cancers. It may help by targeting only the part of the breast where the tumor was, rather than treating the whole breast, while keeping safety and cancer control in mind.
Stuart, FloridaAges 50–100 - NCT05209243Recruiting
Treating limited-spread prostate cancer with radiation plus hormone therapy
This trial studies whether adding focused radiation (SBRT) to hormone therapy can control prostate cancer that has spread to only a few places. It aims to help people with early “oligometastatic” prostate cancer by improving disease control while limiting treatment side effects.
MadridAges Any age - NCT05189054Recruiting
Radiation retreatment for very central chest tumors
This trial tests a focused form of radiation (SBRT) to treat tumors in the very center of the chest that have already been treated with radiation before. It aims to check safety and whether the tumor can be controlled without causing unacceptable side effects.
Beijing, Beijing MunicipalityAges 18–80 - NCT05349552Recruiting
Radiation for lung or chest cancers in specific locations
This trial studies how safe and effective a type of focused radiation called SBRT is for cancer tumors in certain chest locations. It’s meant for people whose tumor is small (up to 5 cm) and who don’t have widespread, uncontrolled spread.
Beijing, Beijing MunicipalityAges 18–80 - NCT07173387RecruitingPhase 2
Radiation plus chemo for locally advanced pancreatic cancer
This trial combines focused radiation with a chemotherapy drug combo to help shrink or control locally advanced pancreatic cancer. If it works, this treatment might make the tumor smaller and improve quality of life.
Jinan, ShandongAges 18–75 - NCT06491472RecruitingPhase 2
Ivonescimab with radiation and chemo for pancreatic cancer
This trial tests a new immunotherapy drug (ivonescimab) combined with targeted radiation and chemotherapy for people with pancreatic cancer. The goal is to see if this combination can shrink tumors and improve outcomes.
WuhanAges 18 years+ - NCT07809672Recruiting
Stereotactic body radiation therapy for spinal metastases
This trial tests a precise type of radiation therapy for cancer that has spread to the spine. The goal is to see if this treatment is safe and effective in reducing the tumor while protecting your spinal cord and improving your quality of life.
TianjinAges 18 years+ - NCT07797816RecruitingPhase 2
Targeted drug combo with radiation for advanced bile duct cancer
This trial tests a combination of two chemotherapy drugs and an immunotherapy drug, followed by targeted radiation, in people with bile duct or gallbladder cancer that cannot be removed with surgery. The goal is to see if this approach can shrink tumors and improve outcomes.
Nanjing, JiangsuAges 18–80 - NCT07770100RecruitingPhase 2
Matching immunotherapy and targeted radiation for advanced cancer
This trial tests combining immunotherapy (a treatment that boosts your immune system to fight cancer) with a targeted type of radiation called SBRT, which precisely delivers high-dose radiation to multiple cancer spots. The main goal is to see if this combination helps control metastatic cancer (cancer that has spread) better than standard care.
Lexington, KentuckyAges 18–99 - NCT07686380RecruitingPhase 2
IL-15 treatment with or without vaccine for prostate cancer
This trial tests a drug called IL-15 superagonist (with or without a vaccine) for men whose prostate cancer has come back (shown by rising PSA) after they already had targeted radiation therapy. The goal is to see if this treatment can lower or control PSA levels.
Bethesda, MarylandAges 18–120 - NCT06664996RecruitingPhase 2
Immunotherapy plus radiation before surgery for liver cancer with portal vein tumor clot
This trial tests combining an immunotherapy drug (sintilimab) with focused radiation (SBRT) before surgery for liver cancer that has spread into a branch of the portal vein. The goal is to see if this combination can shrink the tumor and make surgery more successful.
Chengdu, SichuanAges 18 years+ - NCT04854213Recruiting
Study checks radiation effects in colon cancer lung-limited spread
This trial studies how targeted radiation (SBRT) affects cancer biology and immune cells in people with colon cancer that has spread only to a small number of lung nodules. Your tumor tissue will be analyzed to see what changes after treatment.
Naples, NAPOLIAges 18–80 - NCT07619599RecruitingPhase 1
PET Scan to Track Lung Cancer Treatment Response
This study uses a special PET imaging scan to help doctors see how well pembrolizumab (an immunotherapy drug) is working against advanced non-small cell lung cancer. You'll receive the scan along with your regular pembrolizumab treatment and possible radiation therapy to help measure treatment response.
Duarte, CaliforniaAges 18 years+ - NCT06705127RecruitingPhase 2
Radiation, chemo, and immunotherapy for HR+ breast cancer
This trial tests if giving radiation first, then chemo with an immunotherapy drug called Toripalimab, can help treat a certain type of breast cancer that has not spread to other organs. It is for people with hormone receptor positive, HER2 negative breast cancer that is growing fast.
Hangzhou, ZhejiangAges 18–75 - NCT07600268RecruitingPhase 2
Radiation plus maintenance drugs for advanced pancreatic cancer
This trial tests whether adding a focused radiation treatment (SBRT) to ongoing chemotherapy drugs works better than the drugs alone for pancreatic cancer that has stabilized or shrunk after initial treatment. The goal is to see if this combination approach helps patients live longer.
Jinan, ShandongAges 18–70 - NCT02185443RecruitingPhase 2
SBRT radiation for liver metastases that can’t be surgically removed
This trial studies stereotactic body radiation therapy (high-precision radiation given in a few sessions) for liver metastases when surgery isn’t possible. It may help shrink or control tumors in the liver and delay progression in people whose cancer has not spread outside the liver (or only to areas treated with a curative plan).
São Paulo, São PauloAges 18 years+ - NCT07578116RecruitingPhase 3
Adding surgery and radiation for her2-positive breast cancer with a few spread spots
This trial tests whether adding surgery and radiation to the usual HER2-targeted treatment helps people with breast cancer that has spread to a few spots. You must have HER2-positive cancer that is newly spread, and you must be able to receive radiation to all tumor sites.
Jonesboro, ArkansasAges 18 years+ - NCT07538024Recruiting
Reduced-dose radiation for spine cancer spread
This trial tests whether lower radiation doses work well for treating cancer that has spread to the spine. If you have a few spine tumors that are stable or causing symptoms, this study might help doctors find safer, faster treatment options.
Negrar, VeronaAges 18 years+ - NCT07530172RecruitingPhase 2
Radioembolization vs. External Radiation for Liver Cancer
This study compares two ways of delivering targeted radiation to treat hepatocellular carcinoma (liver cancer): radioembolization, which uses tiny beads to deliver radiation directly through blood vessels, and external beam radiation therapy, which aims radiation from outside the body. The trial will help doctors understand which approach works better for patients with a limited number of tumors.
Detroit, MichiganAges 18 years+ - NCT06766643RecruitingPhase 2
Stereotactic radiosurgery vs. radiofrequency ablation for liver cancer
This study compares two nonsurgical procedures for liver cancer: stereotactic radiosurgery (focused radiation) and radiofrequency ablation (heat therapy). It is for people whose tumor is in a tricky spot near major blood vessels or other structures, making surgery difficult, and who have not received prior treatment.
TianjinAges 18–75 - NCT07426055RecruitingPhase 2/Phase 3
Prostate cancer radiation boost comparison study
This trial compares two types of radiation treatments for prostate cancer that has not spread to lymph nodes or other parts of the body. It tests whether adding a higher dose of radiation to the main tumor helps control the cancer better than standard radiation alone.
Zamość, Lublin VoivodeshipAges 18 years+ - NCT07426094RecruitingPhase 2/Phase 3
Boosting radiation for prostate cancer in lymph nodes
This trial tests whether giving higher radiation doses to the prostate and pelvic lymph nodes is more effective than treating only the prostate. You may benefit if your prostate cancer has spread to nearby lymph nodes but not to bones or other organs, and you are getting hormone therapy.
Zamość, Lublin VoivodeshipAges 18 years+ - NCT07413523Recruiting
Radiation therapy plus standard care for urothelial cancer with limited spread
This trial tests whether adding targeted radiation therapy to standard drug treatment can help people with urothelial cancer that has spread to a few spots (up to 3 outside the brain). If you are starting your first or second round of systemic therapy, this study may be an option.
Rozzano, MilanAges 18 years+
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Common questions
- Are there clinical trials for stereotactic body radiation therapy (sbrt)?
- Yes. Clin2 currently lists 106 recruiting stereotactic body radiation therapy (sbrt) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stereotactic body radiation therapy (sbrt) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stereotactic body radiation therapy (sbrt) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.