Clinical trials
Radical Prostatectomy clinical trials
Below are recruiting radical prostatectomy clinical trials, each written for real people, not researchers. We’re tracking 93 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06875258RecruitingPhase 4
Penile rehab after nerve-sparing prostate surgery
This trial tests a penile rehabilitation program for men who have nerve-sparing prostate cancer surgery. It aims to help improve erections and sexual function after the procedure.
Nijmegen, GelderlandAges 18–70 - NCT06318559Recruiting
3D augmented reality vs. standard robot prostate surgery
This trial tests whether adding a 3D augmented-reality model to standard robot-assisted prostate surgery can help doctors remove the cancer while better preserving sexual function. It is for men whose MRI shows the cancer may have slightly spread outside the prostate.
Candiolo, TurinAges 40–99 - NCT07724028Enrolling by invitation
Nerve stimulation during robotic prostate surgery
This study tests whether stimulating specific nerves during robotic prostate surgery helps preserve erectile function. If you are scheduled for prostate surgery and have normal erections now, this research may help improve your recovery of erections afterward.
LjubljanaAges 18 years+ - NCT06803602Enrolling by invitation
Magnetic therapy for urine leaks after prostate surgery
This trial tests a non-invasive magnetic treatment (HIFEM) to help men with urine leaks after prostate cancer removal (radical prostatectomy) or HoLEP surgery. The goal is to see if it improves bladder control and quality of life.
Scottsdale, ArizonaAges 18–100 - NCT06631521RecruitingPhase 1
Hormone pills before prostate cancer surgery
This trial tests two oral hormone drugs (darolutamide and relugolix) given before prostate removal surgery for men with high-risk prostate cancer. The goal is to see if this combination shrinks the tumor and improves treatment outcomes.
Orlando, FloridaAges 18 years+ - NCT04894188Recruiting
Hormone plus radiation before prostate surgery for high-risk cancer
This trial studies giving hormone treatment and radiation before prostate surgery to treat high-risk, locally advanced prostate cancer. It aims to improve cancer control by shrinking or controlling the tumor before removing it.
Douliu City/Huwei Township, Yunlin CountyAges 20–75 - NCT06822452Recruiting
Outpatient vs. inpatient robotic prostate removal study
This study compares recovery experiences for men having robot-assisted prostate removal surgery as an outpatient (going home the same day) versus staying overnight in the hospital. It looks at early complications to see which approach might work better for eligible patients.
AvignonAges 18 years+ - NCT07205783Enrolling by invitation
Comparing surgery and radiation for early prostate cancer
This trial compares two standard treatments for prostate cancer that hasn't spread: surgery to remove the prostate (radical prostatectomy) and radiation therapy (curative radiotherapy). It looks back at past patients to see which treatment worked better.
SohagAges 40 years+ - NCT02971358Recruiting
Surgery for very high-risk or limited-spread prostate cancer
This trial looks at how safe and how well early prostate surgery works for men with newly diagnosed very high-risk prostate cancer or a limited number of metastases (cancer spread). It may help some people live longer and control the cancer, but eligibility is very specific.
ViennaAges 18–75 - NCT06981026Recruiting
Checking if remote health coaching helps before prostate surgery
This study tests whether using a smartphone or computer to get health coaching before prostate cancer surgery helps people recover faster and have better results. You will be asked to exercise and track your health at home while staying connected with your care team.
OlomoucAges 40–80 - NCT05244486Recruiting
RestoreX traction therapy after prostate surgery
This trial studies whether RestoreX penile traction can help preserve erectile function after a prostatectomy (surgery to remove the prostate), especially when nerves are spared. If you qualify, you may be asked to use the device and be followed over time to see how erections change.
Phoenix, ArizonaAges 18 years+ - NCT07711314RecruitingPhase 2
Rezvilutamide after prostate removal for high-risk cancer
This trial tests if a daily pill called Rezvilutamide can prevent prostate cancer from returning in men who had their prostate removed and are at high risk of recurrence. It is for men who cannot or choose not to have radiation therapy.
Nanjing, JiangsuAges 18–75 - NCT06740071Recruiting
Pelvic floor training for urine leakage after prostate surgery
This study tests a special training program using touch and movement to strengthen pelvic floor muscles in men who leak urine after prostate cancer surgery. It may help you regain bladder control more quickly.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT05710861Recruiting
Focal HIFU versus prostate surgery: cost and quality of life
This trial compares focal HIFU (a targeted heating treatment inside the prostate) with prostate surgery, looking at overall cost and quality of life. It may help people with certain early, limited prostate cancers understand which option fits best for them.
BesançonAges 50–75 - NCT06636682RecruitingPhase 2
Vaccine for men with high-risk prostate cancer after surgery
This trial tests a personalized vaccine (FK-PC101) given after prostate removal surgery for men with high-risk prostate cancer. It aims to see if the vaccine can help prevent the cancer from coming back without the need for additional hormone therapy or radiation.
Chicago, IllinoisAges Any age - NCT07426861Recruiting
Nurse-led education before prostate surgery to reduce incontinence
This study tests whether a nurse-led education program and direct referral to a physiotherapist before prostate removal surgery can help reduce urine leakage (incontinence) after the operation. It may help you recover better bladder control.
Beaumont, DublinAges 18 years+ - NCT07491198Recruiting
Head-Down Position and Eye Pressure in Prostate Surgery
This study looks at how the steep head-down position (Trendelenburg) and gas inflation during robot-assisted prostate surgery affect the sheath around the optic nerve. It aims to understand eye pressure changes to improve safety.
Izmir, İzmirAges 18 years+ - NCT07427043RecruitingPhase 3
Opioid-free pain plan for robotic prostate surgery
This trial tests a pain management strategy that avoids opioids during and after robotic prostate surgery. It aims to reduce opioid use and side effects while keeping you comfortable.
Boston, MassachusettsAges 45 years+ - NCT04638088Recruiting
Robot or standard surgery for prostate removal
This trial compares different ways of doing a radical prostatectomy (surgery to remove the prostate): robot-assisted laparoscopy, conventional laparoscopy, or open surgery. It may help improve which approach is best for people having planned prostate removal.
AgenAges 18 years+ - NCT03541928RecruitingPhase 2
Gene therapy with standard treatment for high-risk prostate cancer
This trial combines gene therapy with hormone therapy, radiation, and possibly surgery to treat high-risk prostate cancer. It aims to improve outcomes by adding gene therapy to standard treatments and will require additional biopsies.
Houston, TexasAges 18 years+ - NCT05109910Recruiting
Checking lymph node surgery impact in men having prostate removal
This study looks at whether removing lymph nodes during prostate removal helps predict outcomes in men whose scans do not show spread. It may help improve how doctors decide who benefits from lymph node surgery based on your risk level and scan results.
AmsterdamAges 18 years+ - NCT05406999RecruitingPhase 2
Intense hormone treatment before prostate surgery for high-risk cancer
This Phase 2 trial studies giving strong hormone-based treatment before prostate surgery to shrink and control high-risk, locally advanced prostate cancer. It may help improve surgical success and reduce cancer spread risk, but it requires careful health checks and prior-treatment limits.
Nanjing, JiangsuAges 18–80 - NCT05753566RecruitingPhase 2
Rezvilutamide for prostate cancer PSA rise after prostate surgery
This Phase 2 study tests rezvilutamide in men whose prostate-specific antigen (PSA) starts rising again after the prostate has been removed. It aims to see whether this treatment can help prevent or slow cancer spread after surgery, especially in men without signs of spread on scans.
Nanjing, JiangsuAges 40 years+ - NCT06305832RecruitingPhase 2
Salvage radiation plus hormone therapy with or without rezvilutamide for rising PSA
This trial tests whether adding a new oral hormone blocker (rezvilutamide) to standard salvage radiation and hormone therapy can better control prostate cancer that has come back (rising PSA) after surgery.
Nanjing, JiangsuAges 40 years+
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Common questions
- Are there clinical trials for radical prostatectomy?
- Yes. Clin2 currently lists 93 recruiting radical prostatectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radical prostatectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radical prostatectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.