Clinical trials
Radiotherapy clinical trials
Below are recruiting radiotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,312 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05974475Recruiting
Personalized modeling during targeted lung radiation for early cancer
This trial studies how detailed tests (“multi-omics” modeling) can improve how doctors plan and deliver stereotactic body radiotherapy (SBRT) for early-stage non-small cell lung cancer. It may help make treatment planning more precise for cancers in stages I–II.
Milan, ItalyAges 18 years+ - NCT05975593Recruiting
Study how radiation affects tumor biology in cervical or pancreatic cancer
This study looks at how radiotherapy changes the tumor environment, using lab samples collected during treatment. It may help researchers understand why radiation works differently for different people and could improve future treatment planning.
St Louis, MissouriAges 18 years+ - NCT05976412Recruiting
Radiation to lymph nodes after surgery for higher-risk breast cancer
This trial looks at whether adding targeted radiation to lymph nodes after breast surgery can lower the chance of breast cancer coming back in people with higher-risk, node-negative disease. If you qualify, you may get a planned radiation approach designed for prevention, not treatment of spread.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05978193RecruitingPhase 2
Radiation plus chemo-immunotherapy for advanced esophageal cancer
This trial tests whether adding radiation to a combination of chemotherapy and immunotherapy can help people with stage IV esophageal cancer that has spread. It is for those who haven't had any prior treatment for their cancer.
ShanghaiAges 18 years+ - NCT05987644RecruitingPhase 1/Phase 2
Timing of brain radiation for ALK-positive lung cancer with brain mets
This trial tests whether it is better to delay brain radiation or give it right away in people with ALK-positive lung cancer that has spread to the brain and is causing few or no symptoms. If you are starting alectinib, you may be able to join and help find the best timing for radiation.
Stanford, CaliforniaAges 18 years+ - NCT05992220RecruitingPhase 2
Immunotherapy with or without radiation for liver cancer
This trial tests a combination of two immunotherapy drugs (atezolizumab and bevacizumab) with or without targeted radiation therapy for liver cancer that has invaded the major blood vessels of the liver. The goal is to see if adding radiation helps shrink tumors or slow the disease.
SeoulAges 20–79 - NCT05994170Recruiting
Lower radiation dose to tumor area for early nasopharyngeal cancer
This trial studies whether lowering the radiation dose to a smaller area around the tumor is safe and effective for people with newly diagnosed nasopharyngeal cancer that has not spread. It may reduce side effects while still curing the cancer.
Zhongshan, GuangdongAges 18–70 - NCT06000787Recruiting
MCT imaging for brain tumors and neuroblastoma
This study is for children or young adults already in specific brain tumor or neuroblastoma trials. It looks at how a type of imaging (MCT) might help doctors better understand and treat these cancers.
San Francisco, CaliforniaAges Any age - NCT06012695RecruitingPhase 1/Phase 2
Study of an oral drug for solid tumors or glioblastoma
This trial tests an oral drug called NBM-BMX for people with advanced solid tumors that have not responded to other treatments, or for people with newly diagnosed glioblastoma (a type of brain cancer). The study aims to see if the drug is safe and effective.
Kaohsiung CityAges 18 years+ - NCT06016387RecruitingPhase 2
Drug combo with radiation for HER2+ breast cancer spread to spinal lining
This trial tests a combination of three targeted drugs (tucatinib, trastuzumab, and capecitabine) along with radiation to the brain or spine for people whose HER2-positive breast cancer has spread to the lining of the brain or spinal cord. The goal is to see if this treatment is safe and effective.
Ottawa, OntarioAges 18 years+ - NCT06017895Recruiting
Doxepin rinse for severe swallowing pain during throat radiation
This trial tests a medicated mouth rinse (doxepin) to ease severe pain when swallowing, caused by radiation therapy for nasopharyngeal cancer. It aims to help patients who are currently receiving radiation and have mouth or throat sores.
Guangzhou, GuangdongAges 18 years+ - NCT06019130RecruitingPhase 2
Nivolumab for newly diagnosed nasopharyngeal cancer
This trial tests whether the immunotherapy drug nivolumab (Opdivo) can help treat nasopharyngeal cancer in both children and adults. It is for people who have just been diagnosed and have not yet received any cancer treatment.
AachenAges 3 years+ - NCT06019468RecruitingPhase 2
Pre-surgery Treatment for Advanced Thymic Cancer
This trial tests a new treatment given before surgery for people with advanced thymic carcinoma. It aims to shrink the tumor and make surgery more effective.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06020430Recruiting
Skipping routine radiation for advanced lung cancer after immunotherapy and chemo
This trial tests whether it is safe to skip routine radiation to the tumor bed in patients with stage III lung cancer that has responded well to immunotherapy and chemotherapy. It aims to reduce side effects while still controlling the cancer.
Wuhan, HubeiAges 18–75 - NCT06030440RecruitingPhase 2/Phase 3
Lowering radiation after head and neck cancer surgery
This study tests whether giving a lower dose of radiation after surgery for head and neck cancer is as safe and effective as the standard dose. It aims to reduce side effects while still preventing the cancer from coming back.
Erlangen, BavariaAges 18 years+ - NCT06037902Recruiting
CPAP during radiation for esophageal cancer
This study tests whether using a CPAP mask (which gently pushes air into your airways) during radiation therapy makes treatment safer and more effective for esophageal cancer. It is for adults who are planning radiation and can tolerate wearing the mask.
Ramat GanAges 18 years+ - NCT06043323RecruitingPhase 2
CAR T cells plus radiation for follicular lymphoma
This trial tests a combination of a CAR T-cell therapy (Axicabtagene Ciloleucel) with radiation therapy for people with follicular lymphoma that has come back or not responded to multiple treatments. The goal is to see if adding radiation can make the CAR T cells work better.
Houston, TexasAges 18 years+ - NCT06043193Recruiting
Quality of life study for patients with neuroendocrine tumors getting internal radiation therapy
This study looks at how internal radiation therapy (RIV) affects quality of life in people with neuroendocrine tumors. It aims to understand how well patients tolerate this treatment and how it impacts daily life.
Saint-Priest-en-Jarez, Saint-EtienneAges 18 years+ - NCT06042946Recruiting
Surgery for spinal cord tumors that spread from other cancers
This trial is for adults who have a specific type of spinal cord tumor that has spread from another cancer. It looks at how well a surgery called microsurgical resection works to remove the tumor and what happens to patients before and after the procedure.
Sankt GallenAges 18 years+ - NCT06050317RecruitingPhase 2
Sintilimab plus chemo and radiation for inoperable pancreatic cancer
This trial combines the immunotherapy drug sintilimab with chemotherapy and radiation for people with inoperable locally advanced pancreatic cancer who have not received prior systemic treatment. The goal is to see if this combination shrinks tumors and improves outcomes.
Jinan, ShandongAges 18–75 - NCT06052332Recruiting
Comparing two pre-surgery treatments for older adults with rectal cancer
This study compares two approaches to treating rectal cancer in people age 70 and older who have not yet had surgery. One approach gives chemotherapy and radiation before surgery, and the other adds more chemotherapy after radiation. The goal is to find which plan works better with fewer side effects.
Antwerp, AntwerpenAges 70 years+ - NCT06055517Recruiting
Re-irradiation with low-dose pulses for recurrent glioma
This trial tests a new way to deliver radiation therapy for people whose brain tumor (glioma) has come back after earlier treatment. Instead of standard radiation, it uses very low doses given in pulses, which may be safer for patients who have already had radiation to the head.
Aviano, PordenoneAges 18 years+ - NCT06055881Recruiting
Using radiation to delay changing treatment for breast cancer
This trial tests whether giving radiation to a few growing spots (1-3) can let you stay on your current drug longer, instead of switching to a new one right away. It's for people with metastatic breast cancer whose disease has been stable for months but now shows limited progression.
Scottsdale, ArizonaAges 18 years+ - NCT06059586Recruiting
Pre-hab program for women getting pelvic radiation for cancer
This trial tests a pre-rehabilitation (pre-hab) program to help women stay stronger before and during pelvic radiation for certain cancers. The goal is to see if it improves quality of life and reduces treatment side effects.
Avon, IndianaAges 18 years+
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Common questions
- Are there clinical trials for radiotherapy?
- Yes. Clin2 currently lists 1,312 recruiting radiotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.