Clinical trials
Randomized Controlled Trial clinical trials
Below are recruiting randomized controlled trial clinical trials, each written for real people, not researchers. We’re tracking 628 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04227314RecruitingPhase 3
Apremilast vs placebo for severe recurrent mouth ulcers
This Phase 3 trial tests whether apremilast can reduce severe, recurring mouth ulcers compared with an inactive placebo. It aims to improve ulcer frequency and pain while carefully checking safety.
AmiensAges 18 years+ - NCT06765772Recruiting
Nerve blocks for pain relief during tummy tuck surgery
This trial compares two types of nerve blocks (with numbing medicine) to reduce pain during and after tummy tuck surgery. The goal is to see if combining two blocks works better than one block alone.
Cairo, Cairo GovernorateAges 21–60 - NCT06829797RecruitingPhase 2
Iparomlimab and chemotherapy vs chemotherapy alone for stomach cancer
This trial tests whether adding an immunotherapy drug (Iparomlimab and Tuvonralimab, combined as QL1706) to standard chemotherapy before surgery works better than chemotherapy alone for people with locally advanced stomach or gastroesophageal junction cancer that can be surgically removed.
Jinan, ShandongAges 18–75 - NCT06061848RecruitingPhase 2/Phase 3
Grass pollen allergy shot with vitamin D
This study tests if adding vitamin D to a new type of allergy shot (ILIT) works better than standard allergy drops for grass pollen allergy. It may help if you have moderate to severe seasonal allergy symptoms.
LundAges 18–60 - NCT04126876RecruitingPhase 2
IMO-2125 skin injection for thick, early-stage melanoma
This trial tests whether an injection given into the skin (IMO-2125) can improve outcomes for people with thicker primary melanoma that has not spread to lymph nodes or other organs. Participants also have planned surgery to remove the tumor and check a sentinel lymph node.
AmsterdamAges 18 years+ - NCT05608434RecruitingPhase 1/Phase 2
VR training for improving attention in kids with ADHD
This study tests a virtual reality (VR) program meant to strengthen attention skills in children with ADHD. It compares different VR-based training options and looks at whether kids improve on attention-related thinking skills after the sessions.
Bethesda, MarylandAges 8–16 - NCT06252571RecruitingPhase 2
Melatonin and light therapy for idiopathic hypersomnia
This trial tests whether taking melatonin at night and using a bright light therapy device in the morning can improve excessive daytime sleepiness in people with idiopathic hypersomnia. It is a double-blind study, meaning neither you nor the doctors will know if you are getting the real treatment or a placebo.
StrasbourgAges 18–40 - NCT06283979RecruitingPhase 2
Antibiotic bone filler vs standard care for infected pressure ulcers
This trial tests a special antibiotic bone filler (STIMULAN VG) compared to standard care for people with a serious pressure ulcer that has infected the bone. You need to be able to have surgery to clean and close the wound.
Phoenix, ArizonaAges 18 years+ - NCT06627855Recruiting
Fascial stretch method for jaw pain relief
This study tests a hands-on technique called the fascial distortion model to see if it works better than a sham treatment for reducing jaw, face, or neck pain. It may help if you have had a jaw disorder for at least 3 months.
Merkez, Karabük ProvinceAges 18–64 - NCT06727864RecruitingPhase 3
Short-course treatment for low-risk active lung TB
This trial tests a shorter treatment course (instead of the standard 6 months) for people with low-risk active TB in the lungs. It aims to see if the shorter regimen works just as well and has fewer side effects.
New Taipei City, BangiaoAges 20–99 - NCT06771492RecruitingPhase 3
Antibiotics for chronic back pain with Modic changes
This trial tests whether an antibiotic (amoxicillin) can reduce chronic low back pain in people who have a specific type of bone change (Modic type I) after a past herniated disc. If you qualify, you would receive either the antibiotic or a placebo (inactive pill) for several weeks.
Rotterdam, South HollandAges 18–65 - NCT06785116RecruitingPhase 4
Study on dapagliflozin for heart health after a hypertensive pregnancy
This trial tests a medicine called dapagliflozin (DAPA) to see if it reduces heart risk in women who had high blood pressure or preeclampsia during pregnancy. It is designed for those who had severe blood pressure rises around delivery or a high BNP level, a marker of heart strain.
Ann Arbor, MichiganAges 18 years+ - NCT06834971Recruiting
Inhaled colistin to prevent pneumonia in ventilated patients
This trial tests if inhaling a medication called colistin can prevent ventilator-associated pneumonia (a lung infection) in patients who are on a breathing machine. It aims to reduce the risk for those at high risk of getting an infection from drug-resistant bacteria.
Jinan, ShandongAges 18 years+ - NCT07360418Recruiting
Follow-up study for healed diabetic foot ulcers
This trial checks if diabetic foot ulcers that healed during an earlier study stay closed over time. You can join only if your ulcer fully healed in that previous trial.
Clinton Township, MichiganAges 18 years+ - NCT07391319RecruitingPhase 3
Testing a new treatment for diabetic foot ulcers
This trial tests a new treatment for foot ulcers caused by poor blood flow and diabetes. It compares the new treatment to a placebo (an inactive substance) to see if it helps ulcers heal better.
MoscowAges 18 years+ - NCT07531888Enrolling by invitation
Brain Stimulation to Improve Memory in Older Adults
This study tests whether a non-invasive brain stimulation technique (tDCS) can help improve memory and thinking skills in people aged 60–75 who have noticed mild memory problems. You'll receive either real or sham (placebo) stimulation and undergo cognitive training over several weeks.
Pachuca, HidalgoAges 60–75 - NCT07164781Enrolling by invitation
Probiotics for preventing infections in ICU patients
This trial tests whether probiotics (good bacteria) can help prevent serious infections in critically ill patients in the ICU. If you are very sick and in the ICU, you may be able to join — as long as you don't have certain conditions like cancer or a weakened immune system.
Banhā, Qalyubia GovernorateAges 18 years+ - NCT06091332RecruitingPhase 2
Sirolimus for brainstem cavernoma bleeding
This trial tests if sirolimus, a medicine that may help reduce abnormal blood vessels, can prevent another brain bleed in people who recently had a bleed from a brainstem cavernoma. You would receive either sirolimus or a placebo to see if it works.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06480500RecruitingPhase 2
Online therapy and IV ketamine for severe depression with suicide risk
This study tests whether adding an online therapy (i-CBT) to intravenous (IV) ketamine is better than IV ketamine alone for people with treatment-resistant depression who are also thinking about suicide. You'll receive either ketamine or a comparison drug (midazolam), plus the online therapy, in a hospital setting.
Toronto, OntarioAges 21–65 - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Tucson, ArizonaAges 18–85 - NCT06912763RecruitingPhase 2
Reversing radiation side effects in head and neck cancer
This trial tests a combined treatment (a statin and a drug that helps blood flow) to reverse long-term swelling and tissue hardening caused by head and neck radiation. It may help people who have had these side effects for more than 6 months.
Houston, TexasAges Any age - NCT03368651RecruitingPhase 3
Testing a pre-surgery infusion to improve liver cancer outcomes
This trial tests whether giving medicine directly into the liver blood vessels before surgery can improve survival for people with liver cancer that has a blockage (tumor in the portal vein). It compares this approach plus surgery versus surgery alone in a randomized study.
Guangzhou, GuangdongAges 18–75 - NCT04588285RecruitingPhase 2
Ambroxol for new and early dementia with Lewy bodies
This trial tests whether ambroxol (a mouth medicine) can help people with new or early dementia with Lewy bodies (DLB) or mild cognitive impairment linked to DLB. Participants take the medicine for about 18 months while the study tracks safety and changes over time.
Haugesund, HaugesundAges 50–85 - NCT05501743RecruitingPhase 2
Injection from your own tissue and platelets for wrist arthritis
This Phase 2 trial tests whether an injection made from your own microfat tissue mixed with platelet-rich plasma can reduce pain and improve function in radiocarpal (wrist) osteoarthritis. It compares this approach to a different standard treatment called total wrist denervation.
Marseille, Bouches-du-RhôneAges 18 years+
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Common questions
- Are there clinical trials for randomized controlled trial?
- Yes. Clin2 currently lists 628 recruiting randomized controlled trial studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a randomized controlled trial trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a randomized controlled trial trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.