Clinical trials
Randomized clinical trials
Below are recruiting randomized clinical trials, each written for real people, not researchers. We’re tracking 1,177 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06603103Recruiting
Comparing two knee implants in total knee replacement
This study compares two types of knee implants (SpheriKA and Origin) used in total knee replacement surgery with a specific alignment technique. The goal is to see which one may lead to better outcomes for patients needing a first knee replacement.
MérignacAges 18 years+ - NCT06005103Recruiting
Testing a headband that sends brain pulses for depression
This study tests a new headband that sends gentle electrical pulses to the brain (T-PEMF) to lift depression. You might join if you have moderate to severe depression and don't have certain other conditions or implants.
Frederiksberg, Capital RegionAges 18–65 - NCT06141135Recruiting
Genetic testing in IVF with single embryo transfer
This trial is for women aged 35–40 doing IVF. It compares genetic testing of embryos before transfer to standard care, to see if it improves pregnancy success.
Waltham, MassachusettsAges 35–40 - NCT06593431RecruitingPhase 3
Treating limited spread pancreatic cancer with local therapy
This trial tests whether combining local treatments (like radiation or surgery) with standard care can help people with pancreatic cancer that has spread to only a few spots (oligometastatic disease). The goal is to improve outcomes for this specific group of patients.
Camden, New JerseyAges 18 years+ - NCT06591468Enrolling by invitationPhase 2/Phase 3
Prednisone Plus Ursodeoxycholic Acid for PBC Patients
This trial tests adding prednisone (a steroid) to ursodeoxycholic acid (a bile acid medicine) for people with primary biliary cholangitis who have a specific type of liver inflammation. The goal is to see if the combination works better at controlling the disease than standard care.
Guangzhou, GuangdongAges 18–75 - NCT06584422Recruiting
Online program for depression in older adults
This study tests an online program called Empower@Home that helps older adults with symptoms of depression. It compares the program to usual care to see if it improves mood and well-being.
Ann Arbor, MichiganAges 50 years+ - NCT06581406RecruitingPhase 2/Phase 3
RP2 with nivolumab for untreated uveal melanoma
This clinical trial tests a new treatment called RP2 (a virus that attacks cancer cells) combined with nivolumab (an immunotherapy drug) for people with metastatic uveal melanoma who have never had immunotherapy before. It aims to see if this combination can shrink tumors and improve outcomes.
Scottsdale, ArizonaAges Any age - NCT06568549RecruitingPhase 4
Reducing Immunosuppression in Older Kidney Transplant Patients (RIOT Trial)
This trial tests whether older kidney transplant recipients can safely reduce their immunosuppression medications using a special monitoring tool called Trugraf. If you are over 55, have had a stable transplant, and want to possibly lower your medications, this study may be for you.
Phoenix, ArizonaAges 55 years+ - NCT06577779RecruitingPhase 4
Testing Jornay PM for adult ADHD symptoms into the evening
This study tests if Jornay PM, a long-acting ADHD medication, helps control symptoms, focus, and emotions throughout the day and into the early evening in adults with ADHD. It is an open-label study, meaning everyone knows they are getting the medication, and then they are randomly assigned to different observation groups.
New York, New YorkAges 18–60 - NCT06549465RecruitingPhase 2
Ac-225 rosopatamab for PSMA-positive castration-resistant prostate cancer
This trial tests a radioactive drug (Ac-225 rosopatamab tetraxetan) that targets a protein called PSMA on prostate cancer cells. It is for patients whose cancer has stopped responding to hormone therapy and has spread to other parts of the body.
San Diego, CaliforniaAges 18 years+ - NCT06557460RecruitingPhase 2
Cell implant for advanced dry age-related macular degeneration
This trial tests a patch of retinal cells implanted under the retina to see if it can slow or stop vision loss from advanced dry AMD (geographic atrophy). It may help people whose central vision is already affected.
Huntington Beach, CaliforniaAges 55–90 - NCT06560021Enrolling by invitation
Random biopsies in inflammatory bowel disease surveillance
This trial looks at whether taking random biopsies during a routine colonoscopy is helpful for people with inflammatory bowel disease (IBD) who are at risk for colon cancer. It aims to understand if random biopsies can detect early signs of cancer or pre-cancer.
Birmingham, AlabamaAges 18 years+ - NCT06553872RecruitingPhase 2
Pirtobrutinib and CAR T-cell therapy for mantle cell lymphoma
This trial tests if adding the targeted therapy pirtobrutinib before CAR T-cell treatment (Tecartus) works better for mantle cell lymphoma that has come back or not responded to other treatments. It aims to improve outcomes for patients who are eligible for CAR T-cell therapy.
Stanford, CaliforniaAges 18 years+ - NCT06558214RecruitingPhase 2
Laser surgery, Optune device, and Keytruda for recurrent glioblastoma
This trial tests a combination of MRI-guided laser surgery, a wearable device (Optune) that sends electric fields to the brain, and an immunotherapy drug (pembrolizumab/Keytruda) for people whose glioblastoma has come back. The goal is to see if this approach is safe and works better than standard treatments.
Gainesville, FloridaAges 18–90 - NCT06561087RecruitingPhase 2
Nivolumab injection for high-risk mouth lesions
This trial tests whether injecting nivolumab directly into high-risk pre-cancerous mouth spots can prevent them from becoming cancer. You randomly receive either the drug or a placebo, and the study monitors how the spots change over time.
Houston, TexasAges 18 years+ - NCT05649943Recruiting
New prostate cancer treatment plus local therapy for metastatic cases
This trial studies whether adding apalutamide to standard hormone therapy (ADT) improves outcomes for men with metastatic hormone-sensitive prostate cancer. Some people may also receive local treatments (like surgery or radiotherapy) to control the prostate and nearby areas.
Milan, LombardyAges 18 years+ - NCT06548204RecruitingPhase 2
Antihistamine after a heart attack
This trial tests whether taking an antihistamine medicine called fexofenadine hydrochloride can help people recover better after a heart attack. It is a randomized study, so some participants will receive the medicine and others will receive a placebo (a pill with no active ingredients).
Hangzhou, ZhejiangAges 18 years+ - NCT06546917Recruiting
Cognitive training trial for mild depression with brain scans
This trial tests a computer-based cognitive training program (bWell-D) to see if it can improve thinking skills like memory and focus in people with mild depression. You will also have an MRI brain scan to see how the training affects your brain.
Vancouver, British ColumbiaAges 19–55 - NCT06543537Recruiting
A trial to help patients with advanced ovarian cancer plan their visits
This study tests a program to help patients and their doctors work together to set a plan for each visit. If you have advanced ovarian cancer and are getting chemotherapy at Dana-Farber, you may be able to join.
Boston, MassachusettsAges 18 years+ - NCT06536504Recruiting
Music before brain surgery for stress and pain
This study looks at whether listening to live or recorded music before brain or spine surgery can help reduce stress, improve mood, and lessen pain. You may be able to join if you are scheduled for neurosurgery and can hear and speak English.
Houston, TexasAges 18 years+ - NCT06520098RecruitingPhase 2
BTK inhibitor with or without venetoclax for CLL/SLL
This trial tests whether adding venetoclax to your current BTK inhibitor (like ibrutinib, acalabrutinib, or zanubrutinib) works better than taking the BTK inhibitor alone. It's for veterans with CLL or SLL who have been on a BTK inhibitor for at least six months and have not had their disease get worse on that therapy.
San Francisco, CaliforniaAges 18–80 - NCT05290285Recruiting
Amino acids for anorexia nervosa, compared with placebo
This study tests whether taking certain amino acids can help people with anorexia nervosa. Participants are randomly assigned to amino acids or a placebo (a look-alike with no active ingredient) to see which works better.
Garda, ItalyAges 16–50 - NCT03977207Recruiting
Thyroid hormone supplement for people on dialysis
This trial tests whether taking a thyroid hormone supplement helps people who are on hemodialysis and have borderline-high thyroid lab results (high TSH but normal FT4). It’s studying whether treatment changes thyroid-related outcomes or health while on dialysis.
Orange, CaliforniaAges 18–75 - NCT06513351Recruiting
Predicting postpartum bleeding after delivery
This trial tests a way to predict heavy bleeding after childbirth. It includes people having a vaginal or cesarean delivery and aims to help doctors prepare for and prevent complications.
Nashville, TennesseeAges Any age
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Common questions
- Are there clinical trials for randomized?
- Yes. Clin2 currently lists 1,177 recruiting randomized studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a randomized trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a randomized trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.