Clinical trials
Recurrent clinical trials
Below are recruiting recurrent clinical trials, each written for real people, not researchers. We’re tracking 1,424 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05803018RecruitingPhase 1/Phase 2
Study drug for advanced gynecologic cancer that stopped working
This Phase 1/2 study tests BL-B01D1 in people with recurrent or metastatic gynecologic cancers (such as ovarian, uterine, or cervical cancer) when standard treatments have failed or aren’t options. It focuses on how well the drug works and whether it can be given safely.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05805020Recruiting
Testing a camera tool to check Crohn’s bowel margins
This study looks at using a special handheld imaging tool during surgery to better check the edges (“margins”) of bowel removed for Crohn’s disease in the ileum/near the cecum. It may help surgeons ensure they remove the right tissue and potentially improve surgical planning.
AmiensAges 18 years+ - NCT05808920Recruiting
Salvage surgery study for recurrent head and neck skin-cell cancer
This study looks at how well people do after “salvage” surgery (planned surgery after prior treatment) for recurrent or residual squamous cell cancer in the head and neck. It may help doctors understand which patients benefit most, including how this surgery affects survival and day-to-day function.
DerbyAges 18 years+ - NCT05826067Recruiting
Testing E. coli from repeat urinary infections
This study collects and studies bacteria (E. coli) found in urine from people with urinary tract infections, including those with repeat infections. It may help improve how doctors understand these infections and choose better future treatments.
BrusselsAges 18 years+ - NCT05834413Recruiting
Herbs plus chemo and immunotherapy to prevent lung cancer spread
This study looks at whether staged Chinese herbal medicine added to standard treatment can lower the risk of lung cancer coming back or spreading after surgery. It is for people with stage Ib to IIIb non-small cell lung cancer whose tests show no “driver gene” targets.
Shanghai, Shanghai MunicipalityAges 18–74 - NCT05837455RecruitingPhase 2
Biomarker-guided treatment for early breast cancer before surgery
This trial looks at whether using tumor test results (biomarkers) can help guide the best hormone treatment and chemotherapy before surgery. It focuses on people with stage II or III, ER-positive, HER2-negative breast cancer, with the goal of improving how well the tumor responds before it is removed.
St Louis, MissouriAges 18 years+ - NCT05840302Recruiting
Pain education program to increase activity in chronic low back pain
This trial studies whether teaching “pain neuroscience” (how pain works in the body and brain) helps people with long-term low back pain move more. It compares an education program as part of a multidisciplinary rehab to usual care during your planned hospital stay.
Lamalou-les-BainsAges 18 years+ - NCT05841732Recruiting
Behavior program with exercise to prevent low back pain returning
This trial tests a phone-based behavior change exercise program to help stop low back pain from coming back. It is for people who recently recovered from a recent low back pain episode and can safely do exercises.
Setúbal, Setúbal DistrictAges 18–65 - NCT05847348RecruitingPhase 3
PET scan for rising PSA after prostate cancer treatment
This Phase 3 trial tests whether a special PET scan using 68Ga-PSMA-11 can detect prostate cancer that has returned after surgery or radiation, measured by rising PSA. If the scan works well, it may help doctors find where the cancer is coming back.
BeijingAges 18 years+ - NCT05847569RecruitingPhase 2
Testing alternating doses of belantamab for hard-to-treat myeloma
This Phase 2 trial tests whether alternating doses and schedules of belantamab mafodotin can help people with multiple myeloma that has returned or kept progressing after several prior treatments. You may be eligible if your disease has specific measurable signs and your blood counts and organs are healthy enough for study treatment.
Jacksonville, FloridaAges 18 years+ - NCT05851196Recruiting
Personalized exercise for recurrent low back pain
This study looks at how back muscle features can help tailor an exercise program for people with recurring, non-specific low back pain. It may help by matching exercises to your specific back function and symptoms.
DiepenbeekAges 18–60 - NCT05855811RecruitingPhase 2
Preventing a Second Cancer After Your First Cancer
This Phase 2 trial tests dostarlimab, an immune-based medicine, to help lower the chance of getting a second (new) cancer after treatment for a first solid tumor. It’s for people with higher risk features, and it aims to see whether the drug can prevent or delay second cancers.
CaenAges 18 years+ - NCT05860569RecruitingPhase 1
Gene therapy safety study for inherited high triglycerides and pancreatitis
This Phase 1 trial tests the safety of a gene therapy for people with inherited, hard-to-control high triglycerides (fat in the blood) who have had pancreatitis episodes. It may help by targeting the genes involved in triglyceride control, but the main goal here is to check safety and tolerability.
Beijing, Beijing MunicipalityAges 18–60 - NCT05861505RecruitingPhase 3
Treatment for new liver spread from colon cancer recurrence
This Phase 3 trial studies a treatment approach for people whose colorectal cancer has come back in the liver within 12 months and can be treated with local procedures. It aims to see whether the study treatment can improve outcomes compared with standard care for people with a limited number of liver tumors.
AmsterdamAges 18 years+ - NCT05862337RecruitingPhase 3
New immune plus anti-cancer pills to prevent liver cancer returning
This Phase 3 trial studies anlotinib capsules plus penpulimab (an immune therapy) to help prevent hepatocellular carcinoma from coming back after it has been fully removed or fully destroyed. It may help high-risk patients lower the chance of recurrence and improve survival.
Bengbu, AnhuiAges 18–75 - NCT05866783Recruiting
Blood test to predict cancer coming back after liver transplant
This study uses a blood test (looking at sugars in the blood) to help predict whether liver cancer will come back after a liver transplant. It may help doctors monitor you more accurately and earlier if cancer returns.
GhentAges 18 years+ - NCT05867901Recruiting
Test stopping imatinib early using blood DNA tests
This trial studies whether some people with high-risk GIST can safely take a “drug holiday” (pause imatinib) after surgery. They use a blood test looking for leftover cancer DNA to help decide who may benefit from stopping treatment.
Beijing, Beijing MunicipalityAges 18–75 - NCT05868928Recruiting
MRI study of brain metastasis relapse after focused radiation
This study looks at MRI scan patterns to estimate the risk of brain metastases coming back after stereotactic radiosurgery (such as Gamma Knife or CyberKnife). It mainly helps by finding imaging clues that can guide follow-up after treatment.
SeoulAges 18 years+ - NCT05877872RecruitingPhase 3
Smaller surgery after chemotherapy for recurring nasopharyngeal cancer
This trial tests whether doing a smaller surgery (after chemotherapy works well) can control recurring nasopharyngeal cancer while reducing treatment burden. It is for people whose cancer can be removed by surgery and who respond to an initial course of chemotherapy plus immunotherapy (or another targeted regimen).
Guangzhou, GuangdongAges 18–75 - NCT05884320RecruitingPhase 2
Sacituzumab govitecan for advanced salivary gland cancers
This Phase 2 trial tests sacituzumab govitecan, an anti-cancer medicine, in people with recurrent or metastatic (coming back or spread) secretory gland cancers or related salivary gland cancers. It aims to see how well the treatment can shrink tumors and control disease when surgery or radiation is not a cure.
Houston, TexasAges 18 years+ - NCT05890352RecruitingPhase 2
Add new medicines to standard treatment for returning lymphoma
This Phase 2 study tests whether adding tafasitamab, lenalidomide, tazemetostat, and zanubrutinib (along with standard lymphoma treatment) can improve outcomes in people whose large B-cell lymphoma has returned or not responded. It may help control disease more effectively and improve response duration for eligible patients.
Tucson, ArizonaAges 18 years+ - NCT05892744RecruitingPhase 4
Testing brain scans to help choose depression treatment
This trial studies how brain signals measured by MRI and EEG may help doctors choose the best treatment for depression. It focuses on people with early-onset, long-lasting or recurring major depression, and tests whether these “brain biomarkers” track with treatment choice and response.
Austin, TexasAges 18–65 - NCT05894070Recruiting
Using your voice recordings to spot cancer coming back
This study looks at whether changes in your voice can help detect early return of laryngeal or hypopharyngeal cancer. If you’ve finished curative treatment and are disease-free for a certain period, your voice will be monitored to see if it can signal recurrence sooner.
BernAges 18 years+ - NCT05901545RecruitingPhase 1
Test an iodine-labeled drug to map neck lymph nodes
This Phase 1 study tests a labelling of panitumumab with iodine (111In) to see how well it can identify lymph nodes in head and neck cancer before surgery. The goal is to improve lymph node staging (which can help guide treatment), with the main focus on safety and early performance.
Nashville, TennesseeAges 19 years+
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Common questions
- Are there clinical trials for recurrent?
- Yes. Clin2 currently lists 1,424 recruiting recurrent studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a recurrent trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a recurrent trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.