Clinical trials
Recurrent clinical trials
Below are recruiting recurrent clinical trials, each written for real people, not researchers. We’re tracking 1,423 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06734780Recruiting
Vaping and Crohn's disease return after surgery
This study looks at how vaping versus smoking tobacco affects the return of Crohn's disease after surgery. It may help doctors understand which habit is safer for people who have had their intestine reconnected.
Milan, MichiganAges 18 years+ - NCT07150715RecruitingPhase 2
Radioactive drug plus precise radiation for recurrent prostate cancer
This trial tests a powerful radioactive drug (either alpha or beta) combined with precise radiation to treat prostate cancer that has come back in a few spots outside the prostate. It may help men whose cancer is still hormone-sensitive and has not spread widely.
Los Angeles, CaliforniaAges 18 years+ - NCT07318818RecruitingPhase 1/Phase 2
Revised cell therapy for recurrent brain cancer
This trial tests a new cell therapy (P134 cells) for people whose glioblastoma has come back after standard treatments like radiation or chemotherapy. The therapy uses a patient's own immune cells (PBMCs) to target cancer cells that have specific markers (CD44 or CD133). It also requires a small procedure to place a reservoir under the scalp for drug delivery.
BeijingAges 18–70 - NCT07317154RecruitingPhase 1
Dendritic cell vaccine for HPV type 6 recurrent respiratory papillomatosis
This Phase 1 trial is testing a vaccine made from your own immune cells (dendritic cells) that may help your body fight the virus causing recurrent papillomas in your voice box. It is for people whose papillomas are caused by HPV type 6, who have had at least one recurrence in the past year.
Scottsdale, ArizonaAges 18 years+ - NCT04695782RecruitingPhase 2
Proton radiation for recurrent rectal cancer in the pelvis
This trial studies “pencil beam” proton radiation for rectal cancer that has come back in the pelvis after you already had radiation. It aims to control the recurrence while trying to limit harm to nearby organs.
AarhusAges 18 years+ - NCT07023601Enrolling by invitation
Study of sentinel node detection in recurrent vulvar cancer
This study tests whether a special dye injection can reliably find the first lymph node that might contain cancer in women whose vulvar cancer has come back for the first time. It aims to help doctors know if the cancer has spread without removing many lymph nodes.
Madrid, MadridAges 18 years+ - NCT05467891RecruitingPhase 2
Ribociclib plus hormone therapy for recurrent breast cancer
This trial tests whether adding ribociclib (a targeted pill) to hormone therapy can control breast cancer that has come back in the breast area or nearby lymph nodes/chest wall. It targets hormone-receptor–positive and HER2-negative tumors to help slow disease after local treatment.
Birmingham, AlabamaAges 18 years+ - NCT06640725RecruitingPhase 2
TPEx chemo with maintenance immunotherapy for advanced head and neck cancer
This trial tests a combination of chemotherapy drugs (TPEx) followed by two immunotherapy drugs (avelumab and cetuximab) as a first treatment for head and neck cancer that has spread or come back. It is for people whose tumors show a protein called PD-L1 and who have not had chemotherapy for advanced disease before.
Vandœuvre-lès-NancyAges 18–74 - NCT06892678RecruitingPhase 1/Phase 2
DFMO maintenance for relapsed Ewing sarcoma or osteosarcoma
This trial tests a drug called DFMO given as maintenance therapy to keep cancer from coming back. It is for people under 40 who have finished treatment for relapsed Ewing sarcoma or osteosarcoma and currently show no signs of cancer.
The Bronx, New YorkAges Up to 39 years - NCT06126276RecruitingPhase 2
Testing neratinib with or without palbociclib for HER2+ solid tumors
This trial tests two targeted drugs—neratinib alone or with palbociclib—for people with HER2-positive solid tumors (other than breast cancer) that have returned or not gone away. The goal is to see if blocking HER2 and CDK4/6 can shrink or slow the tumor.
Birmingham, AlabamaAges 18 years+ - NCT06660511RecruitingEarly Phase 1
Combination therapy for HER2-positive platinum-resistant ovarian cancer
This trial tests a combination of two drugs—Disitamab Vedotin and Anlotinib—for patients with ovarian cancer that has come back after platinum chemotherapy. It is designed for people whose tumors show a specific protein called HER2, and it aims to see if the combination is safe and effective.
Changsha, HunanAges 18 years+ - NCT07045857Recruiting
H. pylori recurrence: causes and patterns
This study looks at whether H. pylori infection comes back after treatment and what factors might cause it to come back. It is for people with confirmed H. pylori who have stomach symptoms.
SohagAges 18–75 - NCT03988283RecruitingPhase 1
Personalized DNA vaccine for recurrent childhood brain tumors
This trial tests a personalized DNA vaccine made from your tumor’s DNA (neoantigens) to help your immune system fight the cancer. It is designed for children and young adults with certain recurrent or newly diagnosed brain/spine tumors, after they have had other standard treatments and tumor tissue is available for testing.
St Louis, MissouriAges Up to 25 years - NCT06881537RecruitingPhase 2
Chemo and targeted therapy before surgery for recurrent colorectal cancer
This trial tests a combination of chemotherapy (CapeOX), a targeted drug (bevacizumab), and an immunotherapy (anti-PD1) given before surgery for colorectal cancer that has come back locally (in the same area). The goal is to shrink the tumor and improve surgical outcomes.
ShanghaiAges 18–75 - NCT06813898RecruitingEarly Phase 1
A New Scan for Early Prostate Cancer Recurrence
This study tests a new scanning method (rhPSMA-7.3 PET/CT) to detect prostate cancer recurrence when PSA is slightly high. If your PSA is low but rising, and standard scans haven't found cancer, this scan might help locate it.
Chicago, IllinoisAges Any age - NCT05646550RecruitingPhase 1
Antibody CC-1 for men with returning prostate cancer
This Phase 1 study tests an antibody drug (CC-1) for men whose prostate cancer has come back, based on rising PSA blood tests. It looks at safety and how the treatment affects cancer activity, especially whether it can help control early biochemical recurrence.
TübingenAges 18 years+ - NCT06697106Recruiting
Can an anti-inflammatory drug prevent urethral stricture recurrence?
This trial tests if taking a COX-2 inhibitor (a type of anti-inflammatory) after a procedure to widen a narrowed urethra can lower the chances of the narrowing coming back. It may help men with a short first-time stricture.
New Valley, New Valley GovernorateAges 18 years+ - NCT05930613RecruitingPhase 3
Certolizumab for repeated embryo transfer pregnancy failure
This Phase 3 study tests certolizumab to help people with repeated embryo transfer failures achieve a clinical pregnancy. It may be an option if your infertility has no known cause and you meet the other study checks.
ParisAges 18–40 - NCT06606262Recruiting
Tonsil removal surgery: total vs partial for recurrent tonsillitis
This study compares two different surgeries for treating frequent tonsillitis (sore throats that come back often): removing the entire tonsils versus removing only part of them. It aims to see which approach works better and has fewer side effects.
AalborgAges 15 years+ - NCT06604572Recruiting
TAPP vs open repair for repeat groin hernia
This study compares two surgical methods — TAPP (a laparoscopic, or keyhole, surgery) and open repair — to fix a hernia in the groin that has come back after a previous surgery. The goal is to see which technique works better for this type of repeat hernia.
Kunming, YunnanAges 18–80 - NCT06000527Recruiting
A French study on juvenile recurrent respiratory papillomatosis
This study is creating a national group of patients with juvenile recurrent respiratory papillomatosis, a condition causing wart-like growths in the airway. It aims to learn more about the disease and improve care.
ParisAges Any age - NCT07675980RecruitingPhase 2/Phase 3
Thymosin-α1 for repeated IVF failure
This trial tests whether a drug called thymosin-α1 can help women who have had two or more failed embryo transfers with genetically normal embryos. It aims to improve the chances of successful implantation.
Abu DhabiAges 18–40 - NCT06386315RecruitingPhase 2
Lower dose radiation for slow-growing lymphoma
This trial tests whether giving a lower dose of radiation than usual works well for people with slow-growing B-cell lymphomas. It aims to reduce side effects while still controlling the disease.
Scottsdale, ArizonaAges 18 years+ - NCT06175208Enrolling by invitation
Online tapping or mindfulness to ease fear of cancer return
This study tests two online programs—Emotional Freedom Techniques (tapping) and mindfulness meditation—to help cancer survivors reduce fear of their cancer coming back. You may join if you finished cancer treatment within the last 5 years and have significant worry about recurrence.
Brasschaat, AntwerpAges 18 years+
Hear when a new Recurrent trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for recurrent?
- Yes. Clin2 currently lists 1,423 recruiting recurrent studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a recurrent trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a recurrent trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.