Clinical trials
Replacement clinical trials
Below are recruiting replacement clinical trials, each written for real people, not researchers. We’re tracking 507 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07043127Recruiting
Strength training after hip replacement with blood flow restriction
This trial tests a new kind of physical therapy after hip replacement. It combines strength exercises with a special technique called blood flow restriction to see if it helps you recover muscle strength faster.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT06997224Recruiting
Breathing exercises after heart valve surgery
This trial tests two breathing exercises (Triflow and deep breathing with cough) to see if they help patients recover lung function after mitral valve replacement surgery. It may help you breathe better after your procedure.
IstanbulAges 18–80 - NCT07016243Recruiting
Knee recovery and ankle movement after knee replacement
This study looks at how well patients can move their ankle after knee replacement surgery and whether it affects their knee recovery. It may help improve rehabilitation for future patients.
Bagheria, PalermoAges 65–85 - NCT07023185Recruiting
Cold and compression after knee replacement
This study will test if adding cold and compression therapy after knee replacement surgery can help with pain, swelling, and recovery. You may qualify if you are 50 or older and having a knee replacement with a specific surgeon.
New Orleans, LouisianaAges 50 years+ - NCT07014124Recruiting
Helping smoking fathers quit for their sick child
This study tests whether helping smoking fathers quit can improve their child's health. You and your child will get support through a messaging app, and the child will provide saliva samples.
Hong Kong, PokfulamAges 18 years+ - NCT07007195RecruitingEarly Phase 1
Smart smell app to help you quit smoking
This study tests a smartphone app that uses your sense of smell to help you quit smoking. You'll use nicotine replacement therapy (like patches or gum) and the app to avoid relapse.
Houston, TexasAges 18 years+ - NCT06174610Recruiting
Kidney ultrasound for ICU patients on dialysis
This study looks at how kidney ultrasound can help monitor critically ill patients who need continuous dialysis for acute kidney injury. The results may help doctors better manage treatment.
Opole, Opole VoivodeshipAges 18 years+ - NCT06991517Recruiting
TAVR sizing study for bicuspid aortic valve patients
This study tests a special sizing method (ABC algorithm) to help doctors select the right valve for people with a bicuspid aortic valve. It aims to improve outcomes for those getting a Sapien 3 valve through a catheter (TAVR).
St Leonards, New South WalesAges Any age - NCT06989229Recruiting
Nutritional care before and after joint replacement surgery
This trial tests if special nutritional support before and after hip or knee replacement helps you recover faster. It is for people having planned (not emergency) surgery.
Brno, CzechiaAges 18 years+ - NCT06972719Recruiting
Hormone therapy after ovary removal for BRCA mutation carriers
This study looks at giving hormone therapy after ovary and fallopian tube removal in women with a BRCA mutation. The goal is to help manage menopause symptoms while you are still premenopausal.
Chapel Hill, North CarolinaAges 19–50 - NCT06966362RecruitingPhase 4
Help cutting back on smoking for veterans not ready to quit
This study tests a medicine called varenicline (also known as Chantix) to help veterans who aren't ready to quit smoking yet but want to cut down. The goal is to see if it helps reduce how much they smoke.
San Diego, CaliforniaAges 21 years+ - NCT06954792Enrolling by invitation
Studying heart changes after tricuspid valve replacement
This study looks at how the heart adjusts after a procedure to replace the tricuspid valve (the valve between the right upper and lower heart chambers). It focuses on patients who need medication to support their blood pressure within 24 hours after the procedure, to better understand and manage this unstable period.
New York, New YorkAges 18 years+ - NCT06948058Recruiting
E-cigarettes vs nicotine therapy for quitting smoking in obesity
This study compares e-cigarettes and nicotine replacement therapy (like patches or gum) to help people who are obese quit smoking. Participants use a study product for 8 weeks and track progress with a smartphone app.
Providence, Rhode IslandAges 21 years+ - NCT06925880Recruiting
Can creatine help seniors recover strength after knee replacement?
This trial tests if taking creatine supplements can help people aged 65+ rebuild muscle mass and strength more quickly after total knee replacement surgery. Participants will take creatine during their standard outpatient rehab program.
Mataró, BarcelonaAges 65 years+ - NCT06928948Enrolling by invitation
Medium-term results of LPS thigh bone replacement
This study looks at how well the LPS™ system works for replacing the lower part of the thigh bone. It aims to find out the medium-term results for people who had this surgery.
BrestAges Any age - NCT06925776Recruiting
Community health workers for kidney disease patients
This trial tests whether a community health worker can help patients with advanced kidney disease get better care and education about home dialysis. The goal is to improve patient involvement and make it easier to navigate social needs.
The Bronx, New YorkAges 18 years+ - NCT06917586Recruiting
Mosaic mitral valve study for patients under 65
This study looks at long-term results in people under 65 who received a specific type of replacement heart valve (the Mosaic mitral valve) during surgery at ProMedica Toledo Hospital. It aims to understand how well the valve works over time.
Toledo, OhioAges 18–65 - NCT04677907Recruiting
Testing a metal knee implant feature in osteoarthritis surgery
This trial studies a specific type of knee replacement and how well it works after surgery for people with knee osteoarthritis. It may help doctors understand which implant approach leads to better outcomes and recovery.
Glasgow, ScotlandAges 18 years+ - NCT06891378Recruiting
Home rehab app for patients after shoulder replacement surgery
This trial tests a digital rehab program you can do at home after reverse total shoulder replacement. The goal is to see if an app-based exercise plan helps you recover safely and effectively.
Seoul, Irwon-ro 81Ages 50 years+ - NCT06880250Enrolling by invitation
Enzyme therapy study for Fabry disease patients
This trial tests if enzyme replacement therapy works well and is safe for Fabry disease. It is for people who are already prescribed this treatment.
AstrakhanAges 8–65 - NCT05100966Recruiting
Exercise program for people waiting for hip or knee replacement
This trial tests a “getting fit” program to help people who are somewhat frail before hip or knee replacement surgery. It aims to improve fitness while you wait for surgery, which may help you feel stronger for recovery.
Calgary, AlbertaAges 60 years+ - NCT06808854Recruiting
Comparing two types of dental implants for a missing back tooth
This trial compares two types of dental implants (variable-thread and standard) for replacing a single missing back tooth. It aims to see which implant works better for long-term stability and healing.
DubaiAges 18 years+ - NCT06869343Recruiting
Early vs. Late Rehab After Shoulder Replacement for Fracture
This study compares starting shoulder rehab early (2 weeks after surgery) versus at the standard time after a reverse total shoulder replacement for a broken shoulder. It aims to see which approach helps you recover better.
Charlottesville, VirginiaAges 50–85 - NCT06871774Recruiting
One vs. two closure devices for TAVR access site
This trial compares using one versus two Perclose devices to close the large hole in the leg after a TAVR procedure. It aims to find which method works better to prevent bleeding and other complications.
Milwaukee, WisconsinAges 18 years+
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Common questions
- Are there clinical trials for replacement?
- Yes. Clin2 currently lists 507 recruiting replacement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a replacement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a replacement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.