Clinical trials
Replacement clinical trials
Below are recruiting replacement clinical trials, each written for real people, not researchers. We’re tracking 502 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06174610Recruiting
Kidney ultrasound for ICU patients on dialysis
This study looks at how kidney ultrasound can help monitor critically ill patients who need continuous dialysis for acute kidney injury. The results may help doctors better manage treatment.
Opole, Opole VoivodeshipAges 18 years+ - NCT06177184Recruiting
Donor milk for full-term cesarean-born babies
This study tests whether giving donor breast milk to full-term babies born by C-section can improve their gut health. If your baby was born by C-section and you plan to breastfeed, this trial may be a good fit.
Calgary, AlbertaAges 9 months+ - NCT06188806Recruiting
Nerve block location study for knee replacement pain
This study compares two types of nerve blocks (proximal vs. distal adductor canal block) for pain relief after knee replacement surgery. The goal is to see which approach provides better pain control and recovery.
Istanbul, UmraniyeAges 18–85 - NCT06234631RecruitingPhase 2
CBD to reduce opioids after knee replacement
This study tests if a daily CBD capsule can help reduce the need for opioid pain pills after a first-time total knee replacement. It is for people with osteoarthritis who are having surgery and are willing to avoid cannabis for a short time before and after.
Ann Arbor, MichiganAges 18–80 - NCT06247267Recruiting
Hormone replacement therapy in military members
This study is looking at how sex hormone replacement therapy affects active-duty military members and their families. It aims to understand the effects in people with low testosterone or those receiving gender-affirming hormones.
Bethesda, MarylandAges 18–65 - NCT06257043Recruiting
Real-world study of aortic valve replacement
This trial is studying how well a new type of heart valve works in real-life patients with aortic valve disease. It will help doctors understand if this valve is safe and effective for people who need a procedure called TAVR (transcatheter aortic valve replacement).
Xi'an, ShaanxiAges 18 years+ - NCT06272422Recruiting
Comparing hip replacement surgeries with 3D planning
This study compares three types of hip replacement surgery (total hip, Minihip, and RSA) using 3D imaging to see which one best restores normal hip function. It might be a good fit if you are planning one of these surgeries and have a healthy other hip.
LilleAges 18 years+ - NCT06290336Recruiting
Exercise and education before knee replacement surgery
This study tests if exercise therapy and patient education before total knee replacement can improve recovery. It may help people waiting for their first knee replacement due to osteoarthritis.
Linköping, Östergötland CountyAges 40–85 - NCT06308757Recruiting
Studying a very low calorie keto diet for fatty liver disease with scarring
This trial tests whether a very low calorie ketogenic diet (a strict low-carb, high-fat diet) can help people with non-alcoholic steatohepatitis (NASH) who have liver scarring. Participants will follow this diet for a year and have two liver biopsies to see if their liver health improves.
BolognaAges 18 years+ - NCT06309563Recruiting
Essential amino acid diet for severe obesity
This study tests whether replacing some foods with essential amino acids (protein building blocks) can improve metabolism in people with severe obesity. It aims to find a non-surgical way to boost weight loss.
Oggebbio, VerbaniaAges 45–65 - NCT06369064Recruiting
Comparing dialysis methods for kidney injury in the ICU
This trial compares two types of dialysis (hemodialysis and hemodiafiltration) to see which is better at removing waste from the blood in ICU patients with sudden kidney failure. It may help doctors choose the best treatment for you.
NîmesAges 18 years+ - NCT06376422Recruiting
Donated meniscus implant for partial knee cartilage loss
This trial tests a donated human meniscus implant (Spongioflex®) for people who have lost part of the wedge-shaped cushion in their knee and have pain on that side. The goal is to replace the missing piece and relieve pain, helping you avoid or delay more serious surgery.
DortmundAges 18–60 - NCT06379386Recruiting
Long-term results of TAVR for severe aortic valve regurgitation
This trial follows people who have severe aortic valve regurgitation and get a TAVR. It looks at how well the valve works over time and how patients do in the long run.
Xi'an, ShannxiAges 18 years+ - NCT06383273RecruitingPhase 3
Study of MELT-300 for sedation during cataract surgery
This trial tests a new sedative medication, MELT-300, to help you relax during cataract surgery. It's for people having surgery on one eye and aims to see if it works better than standard care.
Chico, CaliforniaAges 18–65 - NCT06397456Recruiting
Kidney education program for Black patients in the hospital
This study tests whether a special education and referral program helps Black patients with advanced kidney disease learn about their treatment options before they need dialysis or a transplant. If you join, you will get extra support while you're in the hospital.
Chicago, IllinoisAges 18–70 - NCT06420830Recruiting
Study of a new heart valve in TAVR
This study follows patients with severe aortic stenosis who get a new heart valve (the SAPIEN 3 Ultra RESILIA) through a less invasive procedure (TAVR). Researchers want to see how well this valve works over time using special heart ultrasound tests.
Québec, QuebecAges 18–80 - NCT06440317Recruiting
Study of a special filter for kidney dialysis in septic shock
This trial tests whether a special type of dialysis filter (oXiris) helps reduce blood clotting problems in patients with septic shock and kidney failure. It may offer a better option for those needing kidney support in the ICU.
PessacAges 18 years+ - NCT06462170Recruiting
Measuring insulin production in type 2 diabetes
This study tests how well your body makes insulin by having you drink a Boost shake and checking your blood. It's designed for people with type 2 diabetes who are not yet on insulin.
Ottawa, OntarioAges 18 years+ - NCT06474182Recruiting
Apixaban for blood clots in myeloma patients
This study looks at how Apixaban (a blood thinner) works in people with newly diagnosed multiple myeloma. It compares them to people having knee replacement surgery. The goal is to see if the drug prevents clots effectively in both groups.
Saint-EtienneAges 18 years+ - NCT06477159RecruitingPhase 4
Enzyme replacement for acute pancreatitis recovery
This trial tests whether a pancreatic enzyme replacement therapy (PERT) can help people who still have digestive problems after a recent episode of acute pancreatitis. The goal is to see if it improves symptoms like stomach pain, bloating, or diarrhea.
Los Angeles, CaliforniaAges 18 years+ - NCT04867317RecruitingPhase 3
Growth hormone treatment for veterans with mild TBI and deficiency
This Phase 3 study tests whether replacing growth hormone in veterans with mild traumatic brain injury (mTBI) and low adult growth hormone can improve quality of life. If you qualify, you’ll be screened with hormone blood tests and memory/mental health checks before starting treatment.
Birmingham, AlabamaAges 21–55 - NCT06497894RecruitingPhase 4
Hormone therapy for sleep in late menopause
This trial tests whether hormone replacement therapy (HRT) can improve sleep for women in late menopause who have insomnia. If you are in late menopause and struggle with poor sleep, this study may offer a treatment option.
BernAges 45–69 - NCT06506201Recruiting
Hip replacement methods and leg length difference
This study compares two ways to perform hip replacement to see which one helps reduce leg length differences after surgery. The findings could help people with severe arthritis get better alignment and feel more comfortable.
BolognaAges 50–80 - NCT06507046Recruiting
Personalized total knee replacement study in Norway
This trial is studying a more personalized approach to total knee replacement surgery. It is for people with moderate to severe knee arthritis who are already scheduled for a knee replacement at Kristiansund Hospital in Norway.
Kristiansund, Møre and RomsdalAges 18–80
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Common questions
- Are there clinical trials for replacement?
- Yes. Clin2 currently lists 502 recruiting replacement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a replacement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a replacement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.