Clinical trials
Resistance clinical trials
Below are recruiting resistance clinical trials, each written for real people, not researchers. We’re tracking 1,215 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06313684Recruiting
Hybrid cardiac rehab for heart failure patients
This study tests a hybrid cardiac rehab program (both at the clinic and at home) for people with heart failure. It combines supervised exercise sessions with remote support to help improve your heart health and daily function.
SantiagoAges 18 years+ - NCT06321484RecruitingPhase 1
NK cell therapy for recurrent platinum-resistant ovarian cancer
This trial tests a new type of immune cell therapy (CIML NK cells) given directly into the abdomen for women with ovarian cancer that has come back and is now resistant to standard platinum chemotherapy. The goal is to see if these specially trained cells can fight the cancer safely.
Boston, MassachusettsAges 18–85 - NCT06322888Recruiting
Exercise study for women with dense breasts
This trial tests if resistance and aerobic exercise can help prevent breast cancer in women with dense breast tissue. You would join a supervised exercise program to see if it reduces your risk.
Boston, MassachusettsAges 18–59 - NCT06324422Recruiting
Exercise for Parkinson's fatigue
This trial tests if a structured exercise program can reduce fatigue in people with Parkinson's disease. It may help you feel less tired and improve daily function.
Aarhus, Central JutlandAges 40 years+ - NCT05169229RecruitingPhase 2
Antibiotic bone graft to prevent infection in hip replacement
This trial tests whether adding antibiotics to the bone graft used during hip replacement surgery can lower the risk of infection. It may help people who need a bone graft as part of their hip replacement.
Linköping, Region ÖstergotlandAges 18 years+ - NCT07526766Recruiting
Exercise Program for Heart Artery Dissection and Fibromuscular Dysplasia
This study tests whether a supervised exercise program is safe and helpful for people who have had a spontaneous tear in a heart artery (SCAD) or fibromuscular dysplasia (a condition affecting blood vessel walls). The goal is to see if exercise can improve heart health after recovery from these conditions.
Jacksonville, FloridaAges 21–65 - NCT06329908RecruitingEarly Phase 1
Dendritic cell vaccine plus immunotherapy for resistant lung cancer
This trial tests a new treatment combining a dendritic cell vaccine (a type of immune therapy that trains your body to fight cancer) with additional immunotherapy drugs. It is for people with advanced lung cancer that has stopped responding to standard immunotherapy.
Chengdu, SichuanAges 18–85 - NCT06331208Recruiting
Mechanisms of Lung Blood Vessel Problems in Heart Failure
This study looks at how heart failure affects blood vessels in the lungs. If you have heart failure with reduced pumping ability and need a heart catheterization, you may be able to join.
PragueAges 18 years+ - NCT06336733RecruitingPhase 3
Trial of anakinra for FMF attacks in patients who refuse daily shots
This trial tests if taking anakinra (a targeted medicine) only when you have a painful FMF attack can help, instead of taking it every day. It is for people with Familial Mediterranean Fever (FMF) whose attacks continue despite taking colchicine, and who do not want daily injections.
ParisAges 6 years+ - NCT06340789RecruitingPhase 2
Sodium Benzoate Added to Antipsychotics for Resistant Schizophrenia
This study tests whether adding a supplement called sodium benzoate to your current antipsychotic medication can improve symptoms in schizophrenia that hasn't responded well to standard treatments. Researchers will measure brain chemistry changes and symptom improvement over time.
Chiayi CityAges 20–55 - NCT06347068RecruitingPhase 1
CAR-T cell therapy for triple-negative breast cancer
This trial tests a new treatment using your own immune cells, modified to target a protein called B7-H3 on triple-negative breast cancer cells. It may help if other treatments haven't worked.
Chapel Hill, North CarolinaAges 18 years+ - NCT06353620Recruiting
Brain connections study for certain epilepsies and genetic syndromes
This study uses MRI and a special EEG to understand brain connections in people with specific types of epilepsy or genetic conditions like Angelman syndrome and Dup15q. It may help find better ways to treat these conditions.
Conegliano, TrevisoAges 6–75 - NCT06355037RecruitingPhase 2
Dasatinib and quercetin for chemo-resistant triple negative breast cancer
This trial tests whether adding dasatinib and quercetin to your treatment can reverse resistance to chemotherapy in triple negative breast cancer that has spread or come back. It aims to help your body respond better to treatment.
ShanghaiAges 18–70 - NCT06360302Recruiting
Exercise and insulin resistance in dialysis patients
This study looks at how exercise affects muscle metabolism and insulin resistance in people on dialysis, compared to those with metabolic syndrome and healthy individuals. It aims to find blood markers that could help assess insulin resistance in dialysis patients.
MontpellierAges 40–75 - NCT06361160Recruiting
Brain stimulation for treatment-resistant voices in schizophrenia
This trial tests a brain stimulation treatment (rTMS) to help reduce the frequency and intensity of voices people with schizophrenia hear. It is for individuals who continue to hear voices frequently despite trying multiple medications.
ParisAges 18 years+ - NCT06361940RecruitingPhase 2
Short-term hormone therapy before breast cancer surgery
This trial is testing how well a short course of hormone-blocking pills (endocrine therapy) works before surgery in women with early-stage hormone receptor-positive HER2-negative breast cancer. The goal is to understand what makes some cancers resistant to these treatments.
Milwaukee, WisconsinAges 18 years+ - NCT06370988Recruiting
Theta-burst stimulation for bipolar depression
This study tests a type of brain stimulation (theta-burst TMS) to see if it helps improve depression in people with bipolar disorder. It might be a good option if you have tried medication but still feel depressed.
Toronto, OntarioAges 18–65 - NCT06379113RecruitingPhase 2/Phase 3
Hormone therapy for obesity-linked endometrial cancer that didn't respond to progestin
This trial tests a combination of two hormone-blocking drugs (GnRHa plus letrozole) for women with early-stage, obesity-related endometrial cancer who haven't responded well to standard hormone therapy alone. The goal is to preserve the uterus and fertility while controlling the cancer.
Shanghai, Shanghai MunicipalityAges 18–45 - NCT06386796Recruiting
Using ultrasound to predict kidney trouble in high-risk patients
This study uses a simple ultrasound test (kidney artery scan) to see if it can predict kidney problems early in people who are very ill. It may help doctors protect your kidneys during your hospital stay.
Aswān, Aswan GovernorateAges 18–80 - NCT06394492RecruitingPhase 3
Testing a new drug for platinum-resistant ovarian cancer
This study tests a new drug called SHR-A1921 for people with ovarian cancer that no longer responds to platinum chemotherapy. The goal is to see if it can shrink tumors or slow the cancer's growth.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06395519RecruitingPhase 1/Phase 2
Study of ETX-19477 for advanced solid tumors
This trial tests an experimental drug called ETX-19477 for people with advanced solid tumors that have stopped responding to other treatments. It aims to see if the drug is safe and effective, especially for those with certain genetic changes (BRCA2 mutations).
Phoenix, ArizonaAges 18 years+ - NCT06404320Recruiting
Exercise program for treatment-resistant depression
This study tests whether a physical activity program can help adults whose depression hasn’t improved after trying at least two antidepressants. If you’re sedentary, between 18 and 65, and have treatment-resistant depression, this program might offer a new way to feel better through exercise.
Toronto, OntarioAges 18–65 - NCT06406608Recruiting
Personalized drug test for drug-resistant lung cancer
This trial tests a new way to choose your next treatment by growing a mini version of your tumor (an organoid) in a lab and seeing which drugs kill it best. It is for people with drug-resistant non-small cell lung cancer who have already tried at least two standard treatments.
Zhengzhou, HenanAges 18–75 - NCT06410833RecruitingPhase 4
Combination therapy for resistant Sjögren's in children
This trial tests a combination of two medicines, rituximab then belimumab, for children and teens with Sjögren's syndrome that hasn't improved with other treatments. The goal is to see if this two-step approach can better control symptoms like joint pain, skin rashes, and blood problems.
Beijing, Beijing MunicipalityAges 5–18
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Common questions
- Are there clinical trials for resistance?
- Yes. Clin2 currently lists 1,215 recruiting resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.