Clinical trials
Resistance clinical trials
Below are recruiting resistance clinical trials, each written for real people, not researchers. We’re tracking 1,213 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06532123Recruiting
Study on improving muscle control for bowel leakage
This trial tests a treatment to strengthen the muscles that control bowel movements in people with weak anal sphincters. It may help those who have trouble holding in stool or gas.
Milwaukee, WisconsinAges 18 years+ - NCT06532851Recruiting
Exercise therapy for knee cartilage health
This study tests whether specific exercises can improve your knee cartilage health and daily function. It is for people with a meniscus tear who are at risk for knee arthritis but don't have arthritis yet.
Ar RamthaAges 35–55 - NCT06537986Recruiting
Thinking and wellbeing program for people with epilepsy
This study tests a program that combines thinking skills training, emotional support, and social guidance for adults with epilepsy. The goal is to see if this program helps improve memory, mood, and daily life.
ChandigarhAges 18–45 - NCT06542718Recruiting
Studying glucose patterns in Asian women with gestational diabetes
This study monitors blood sugar levels during pregnancy in overweight Asian women to better understand gestational diabetes. It uses a continuous glucose monitor to track patterns and may help improve care for mothers and babies.
SingaporeAges 21–45 - NCT06545214Recruiting
Breathing and arousal in drug-resistant epilepsy
This study looks at breathing problems during seizures in people with drug-resistant focal epilepsy. It aims to understand why some people stop breathing or have low oxygen during seizures, which could help prevent sudden death in epilepsy.
Bron, RhoneAges 18–55 - NCT06545721Recruiting
Weight changes and hormone health in PCOS
This study looks at how weight changes affect hormone levels and insulin resistance in women with PCOS. It may help understand if weight cycling is harmful or helpful.
Beijing, Beijing MunicipalityAges 18–45 - NCT06547840RecruitingPhase 1
Study of MOv18 IgE for ovarian, endometrial, and breast cancers with a specific marker
This trial tests a new antibody treatment called MOv18 IgE for patients with advanced ovarian, endometrial, or triple-negative breast cancers that have a protein called folate receptor alpha (FRα) on their tumor cells. The goal is to see if the treatment is safe and effective.
BristolAges 18 years+ - NCT06552429RecruitingPhase 2
Peginterferon for ET not controlled by hydroxyurea
This trial tests a new injectable medicine (Peginterferon α-2b) for people with essential thrombocythemia (ET) whose disease is not controlled by hydroxyurea (HU) or who cannot tolerate HU. It aims to help lower high platelet counts and reduce the risk of clots or bleeding.
BeijingAges 18 years+ - NCT06553898RecruitingPhase 1
CAR-T cell therapy for hard-to-treat kidney disease
This trial tests a new CAR-T cell treatment for children and adults with steroid-resistant nephrotic syndrome (SRNS), a kidney condition that doesn't get better with standard medicines. The goal is to see if this therapy can help improve kidney function when other treatments have failed.
Hangzhou, ZhejiangAges 2 years+ - NCT06562413Recruiting
Finding New Biological Clues in Hard-to-Treat Migraine
This study looks for new biological markers in people whose migraines don't respond to standard treatments. It aims to better understand why some migraines are hard to treat and may help guide future therapies.
PaviaAges 18–75 - NCT06562400Recruiting
New treatments for resistant migraine
This trial is testing new approaches for people whose migraines haven't improved with multiple preventive treatments. The goal is to find better options for those with hard-to-treat migraine.
PaviaAges 18–75 - NCT06566066Recruiting
Thyroid hormone resistance patient registry
This study creates a registry for people with thyroid hormone resistance caused by specific genetic mutations. It helps doctors collect data to better understand and treat the condition.
BerlinAges Any age - NCT06567015RecruitingPhase 1/Phase 2
STX-241 for advanced EGFR-mutant lung cancer after TKI failure
This trial tests an experimental drug called STX-241 for people with a specific type of advanced lung cancer (NSCLC) that has an EGFR mutation (exon 19 deletion or L858R) and has stopped responding to a third-generation EGFR inhibitor (like osimertinib). The drug aims to target a new mutation, C797X, that sometimes appears after osimertinib stops working.
Nashville, TennesseeAges 18 years+ - NCT06571487Recruiting
Growth hormone resistance in beta cells after pregnancy
This study looks at how the body's insulin-making cells (beta cells) might become resistant to growth hormone after a full-term pregnancy. It compares women who had gestational diabetes to those who didn't, to learn more about diabetes risk. You may join if you had a healthy single-baby pregnancy in the last 5 years and never had type 1 or type 2 diabetes.
Columbia, MissouriAges 18–45 - NCT06571500Recruiting
Growth hormone and insulin cells in type 2 diabetes risk
This study looks at how growth hormone affects insulin-making cells in people at risk for type 2 diabetes. It may help explain why some people with a family history of diabetes develop the condition.
Columbia, MissouriAges 18–59 - NCT06586957RecruitingPhase 1
Study of NKT3964 for advanced solid tumors
This trial is testing an experimental oral drug called NKT3964 for people with advanced solid tumors that have stopped responding to standard treatments. The drug works by blocking a protein called CDK2, which some cancers need to grow.
Little Rock, ArkansasAges 18 years+ - NCT06592261RecruitingPhase 1
Insulin suppression test for weight groups
This study tests a new way to measure how the body handles insulin in people with different body weights. It may help researchers understand insulin resistance better.
New York, New YorkAges 18–65 - NCT06599099Recruiting
Deep brain stimulation for depression that hasn't responded to other treatments
This trial tests if deep brain stimulation (a surgical implant that sends gentle electrical pulses to a specific area of the brain) can help people with bipolar I disorder who are currently in a severe depressive episode and have not found relief from multiple treatments.
Boston, MassachusettsAges 22–64 - NCT06599372Recruiting
TMS for resistant voices in schizophrenia
This trial tests if a non-invasive brain stimulation method called transcranial magnetic stimulation (TMS) can reduce stubborn auditory hallucinations (hearing voices) in people with schizophrenia who haven't improved enough with medication.
Neuilly-sur-MarneAges 18 years+ - NCT05137054RecruitingPhase 1
Linvoseltamab combo for hard-to-treat multiple myeloma
This trial tests a new drug called linvoseltamab combined with other cancer treatments for people with multiple myeloma that has stopped responding to standard therapies. It may be an option if you have already tried several treatments and are looking for a new approach.
La Jolla, CaliforniaAges 18 years+ - NCT07690163Recruiting
Diabetes blood sugar check in newly diagnosed patients
This trial is checking how well blood sugar is controlled in adults recently diagnosed with type 2 diabetes (within the last 3 months). It aims to see if current treatments or lifestyle changes are working and may help guide future care.
KyivAges 18 years+ - NCT06083324Recruiting
Exercise program to improve strength and mobility after cancer
This study tests a personalized exercise program using resistance training (lifting weights) to help cancer survivors rebuild strength, improve body composition, and move better after treatment. It is designed for people who are ready to start exercising safely and want to regain function.
Pittsburgh, PennsylvaniaAges 20–89 - NCT06476288Enrolling by invitation
Remote Ischemic Conditioning in Older Adults Starting Exercise
This study tests a simple, non-invasive treatment called Remote Ischemic Conditioning (RIC) in older adults who have been referred to exercise. RIC involves gently restricting blood flow to the arm for short periods, which may help improve how well your body adapts to exercise.
Durham, North CarolinaAges 65 years+ - NCT06607887RecruitingPhase 4
Antibiotics after gallbladder surgery
This trial tests whether taking antibiotics after laparoscopic gallbladder removal helps prevent infection. It aims to find out if antibiotics are needed for patients without certain health conditions.
MinyaAges 18 years+
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Common questions
- Are there clinical trials for resistance?
- Yes. Clin2 currently lists 1,213 recruiting resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.