Clinical trials
Resistance clinical trials
Below are recruiting resistance clinical trials, each written for real people, not researchers. We’re tracking 1,198 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06781697RecruitingPhase 3
Ketamine and virtual reality for treatment-resistant depression
This trial tests if adding virtual reality to ketamine treatments can help people with depression that hasn't improved with other treatments. You'll receive IV ketamine as prescribed by your doctor and also use a virtual reality headset during sessions.
Toronto, OntarioAges 18 years+ - NCT06773949Recruiting
Exercise before rTMS for hard-to-treat depression
This trial tests if doing exercise before repetitive transcranial magnetic stimulation (rTMS) can improve depression symptoms in people who haven't gotten better with standard treatments.
Ottawa, OntarioAges 18–75 - NCT05393518Recruiting
Study linking brain signals to anxiety in people with epilepsy
This study looks at how brain electrical signals relate to anxiety symptoms in people with drug-resistant epilepsy. It compares people who do (or do not) meet criteria for generalized anxiety disorder, to better understand anxiety in this setting.
BordeauxAges 18–65 - NCT06513624RecruitingPhase 1
ETC-159 plus pembrolizumab for advanced ovarian cancer
This trial tests a new combination of two drugs—ETC-159 (a pill that targets a specific growth pathway) and pembrolizumab (an immunotherapy)—for people with advanced ovarian cancer that has stopped responding to platinum chemotherapy. The goal is to see if this combination can help shrink tumors or slow their growth.
Singapore, SingaporeAges 21–99 - NCT06770660Recruiting
Remote exercise for teen fitness
This trial tests whether exercising at home through video calls can improve heart and lung fitness in teenagers aged 12 to 17. It might be a convenient way to stay active if you cannot get to a gym or sports club.
SingaporeAges 12–18 - NCT06768827Recruiting
Obesity mechanisms study for teens
This study looks at how bodies process food to understand obesity in teenagers. It may help find new ways to prevent or treat obesity.
New Haven, ConnecticutAges 15–22 - NCT06763328RecruitingPhase 3
Metformin for insulin resistance after breast cancer chemo
This study tests if metformin, a common diabetes medicine, can help reduce insulin resistance in women who finished chemotherapy for early-stage breast cancer. It aims to improve long-term health and prevent future problems.
Duarte, CaliforniaAges 18 years+ - NCT06762054Recruiting
Better management for dolutegravir-resistant HIV
This trial tests better ways to manage HIV when the virus becomes resistant to dolutegravir (DTG), a key medicine. It is for people with high viral load despite being on DTG for at least six months.
KisumuAges 1 year+ - NCT05663840Recruiting
Exercise program study for focal neck dystonia
This trial tests how a structured exercise program affects the brain and body changes behind focal cervical dystonia (a movement disorder that causes abnormal neck postures). It may help people who are still having symptoms despite best-available treatments like botulinum toxin injections or medicines.
Gainesville, FloridaAges 30–85 - NCT06757712Recruiting
Resistance training for quality of life in women with hypothyroidism
This trial tests if a special resistance-training schedule can improve quality of life in women with well-controlled hypothyroidism who are also overweight. You will follow a periodized (changing intensity) exercise plan and see how it affects your daily energy and well-being.
SuezAges 35–45 - NCT06745908RecruitingPhase 3
New drug combo for lung cancer after immunotherapy stops working
This trial tests a new drug combination (N-803 and tislelizumab with chemotherapy) for people whose lung cancer stopped responding to standard immunotherapy. The goal is to see if this treatment can help shrink tumors or slow the cancer's growth.
Springdale, ArkansasAges 18–90 - NCT06747507RecruitingPhase 3
Ndovu study: best HIV treatment for drug resistance
This trial is for people with HIV who are not responding well to the drug dolutegravir (DTG). It tests if switching to a different drug, darunavir/ritonavir (DRV/r), works better than continuing DTG when resistance has developed.
KisumuAges 3 years+ - NCT06738771Recruiting
Antibiotic treatment for tough Pseudomonas infections
This study tests a specific antibiotic plan for adults with a hard-to-treat Pseudomonas infection that needs IV medicine. It aims to find the best way to treat these serious infections.
AmiensAges 18 years+ - NCT06748209RecruitingPhase 4
Mobile TMS for treatment-resistant depression
This trial tests if delivering transcranial magnetic stimulation (TMS) through a mobile unit can help people with depression that hasn't improved with other treatments.
Charleston, South CarolinaAges 22–80 - NCT06738394Recruiting
Exercise study for older adults with kidney disease
This study tests whether a supervised exercise program can help older adults with chronic kidney disease improve their physical function and stay active. You have to be able to do exercise and not be on dialysis.
Winston-Salem, North CarolinaAges 65–100 - NCT06732141Recruiting
Phone program for asthma anxiety and medication adherence
This study tests a telephone-based program to help people with asthma who feel anxious about using their daily inhaled steroid medication. It aims to reduce anxiety and improve how well you stick to your treatment plan.
HarbinAges 18–80 - NCT06735651Recruiting
Wild blueberries for gut, brain, and heart health in prediabetes
This study looks at whether eating wild blueberries can improve your gut health, brain function, and heart health if you have prediabetes. It may help lower your blood sugar and reduce your risk for diabetes and heart disease.
Atlanta, GeorgiaAges 20–65 - NCT06731140RecruitingPhase 2
Reversing immune resistance in HER2-negative breast cancer
This trial tests a new treatment to see if it can reverse resistance to immunotherapy in people with HER2-negative breast cancer. It's for patients whose cancer has gotten worse after immunotherapy.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06717594Recruiting
Study of antibiotics for resistant infections
This trial looks at how well two antibiotics, ceftazidime-avibactam and fosfomycin, work together to treat infections caused by highly resistant bacteria called CRE. It may help find the best way to use these medicines.
Bologna, BolognaAges 18 years+ - NCT06718699Enrolling by invitation
Calculating your maximum strength accurately
This trial tests whether simple calculations can predict your maximum strength instead of doing heavy lifts. If you're in the right age group, you might help improve strength testing for everyone.
ErlangenAges 18–85 - NCT06724029Recruiting
Neurosurgery outcomes research for multiple conditions
This study collects data from people having brain or spine surgery for many different conditions. It aims to understand how well different treatments work and how people recover. If you are scheduled for certain brain, spine, or nerve surgeries, you may be able to join.
Bergamo, BGAges 18 years+ - NCT05690048RecruitingPhase 2
Fecal transplant to help liver cancer respond to standard drugs
This trial studies whether a fecal microbiota transfer (a “gut bacteria transfer” from a donor) can help liver cancer patients overcome resistance to atezolizumab and bevacizumab. It aims to improve how well the standard medicines control the cancer.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06213636RecruitingPhase 1/Phase 2
New CAR T cells for resistant B-cell leukemia or lymphoma
This trial tests a new type of CAR T-cell therapy that targets two specific markers (CD19 and CD22) on cancer cells. It is for people ages 1 to 30 with hard-to-treat B-cell leukemia or lymphoma that has not responded to standard treatments.
Beijing, Beijing MunicipalityAges 2–90 - NCT06714357RecruitingPhase 2
Valproic Acid to Boost Anti-EGFR in Colorectal Cancer
This trial tests whether adding valproic acid to standard anti-EGFR plus irinotecan can stop or reverse resistance in metastatic colorectal cancer. It is for patients who previously responded well to an anti-EGFR drug and then progressed.
Caserta, CEAges 18 years+
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Common questions
- Are there clinical trials for resistance?
- Yes. Clin2 currently lists 1,198 recruiting resistance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a resistance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a resistance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.