Clinical trials
Retinopathy clinical trials
Below are recruiting retinopathy clinical trials, each written for real people, not researchers. We’re tracking 116 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06549023Recruiting
One session vs multiple sessions of laser for diabetic eye disease
This study compares having laser treatment for diabetic eye disease in one session versus spreading it over multiple sessions. The goal is to find out if one approach is better for your eyes and easier for you.
MölndalAges 18 years+ - NCT07351786Recruiting
Newer diabetes drugs and eye protection study
This trial is looking at whether newer diabetes drugs (like SGLT2 inhibitors and DPP-4 inhibitors) can help protect the eyes of people with long-standing type 2 diabetes. The study focuses on preventing or slowing diabetic retinopathy, a common eye complication.
AlexandriaAges 25 years+ - NCT04819893Recruiting
Study fatty acids and eye disease risk in newborns
This study looks at whether fatty acids from the mother are linked to the risk of retinopathy of prematurity, an eye condition that can affect very premature babies. It involves checking factors related to how the body responds to fatty acids during pregnancy and comparing mothers in different pregnancy situations.
DijonAges 18 years+ - NCT06582472Recruiting
Early eye changes and diabetes trial
This study looks at early damage to the retina (the back of the eye) in people with type 2 diabetes, even before vision problems start. It aims to find new ways to detect and treat diabetic eye disease early.
Milan, Italy/milanAges 40–80 - NCT06713720Recruiting
Arm Cuff Therapy for Early Diabetic Eye Disease
This study tests if a simple, non-invasive treatment called remote ischemic conditioning (briefly restricting blood flow to one arm using a special cuff) can help slow down early-stage diabetic eye disease in people with type 2 diabetes. You join the study to potentially prevent your retinopathy from getting worse.
Beijing, Beijing MunicipalityAges 40–80 - NCT06914778Recruiting
How diabetes affects the eyes in South Wales
This study looks at how fat and sugar levels in the blood relate to different stages of eye damage in people with type 2 diabetes. It may help find new ways to treat or prevent vision loss.
Llanelli, WalesAges 18–80 - NCT07069647Recruiting
AI screening for diabetic eye disease and macular degeneration
This trial tests if an AI tool can help detect diabetic retinopathy and age-related macular degeneration in older adults visiting family medicine or geriatric clinics. It aims to catch these eye conditions early, before they cause vision loss.
TaipeiAges 20 years+ - NCT07592273RecruitingPhase 2/Phase 3
Gene therapy for diabetic eye disease without macular swelling
This trial tests a gene therapy injection into the eye to treat diabetic retinopathy (eye damage from diabetes) before it progresses. The goal is to slow or prevent vision loss and potentially delay the need for laser treatment or other injections.
Phoenix, ArizonaAges 18 years+ - NCT05844982RecruitingPhase 3
Eye injections or steroid implant to prevent vision loss
This trial studies ways to prevent worsening vision caused by radiation damage to the retina after plaque brachytherapy for uveal melanoma. You may be randomly assigned to a medication injection, a steroid implant, or observation to see which approach best protects vision.
Palo Alto, CaliforniaAges 18 years+ - NCT07758582Recruiting
Artificial intelligence for detecting diabetic retinopathy from eye photos
This study tests an AI system that automatically detects signs of diabetic retinopathy from eye photos. It aims to see if the AI can accurately identify these signs to help with early detection.
AlexandroupoliAges 18 years+ - NCT06612541Recruiting
Eye imaging test for premature babies at risk of ROP
This study tests a new eye imaging device to check for retinopathy of prematurity (ROP), a condition that can affect vision in premature babies. It may help doctors diagnose ROP earlier and more easily at the bedside.
Nashville, TennesseeAges 6 months–8 months - NCT06817265RecruitingPhase 3
TNTL for diabetic eye disease (non-proliferative)
This study tests if a drug called TNTL can help people with type 2 diabetes who have early-stage diabetic eye disease (non-proliferative diabetic retinopathy) without severe vision loss. It aims to see if the treatment is safe and effective in slowing or improving the condition.
Xuancheng, AnhuiAges 18–75 - NCT06412224RecruitingEarly Phase 1
Testing a new drug for diabetic eye disease after vitrectomy
This trial tests a new medicine, RRG001, given after vitrectomy surgery for severe diabetic eye disease. It aims to see if the drug is safe and helps prevent vision loss.
TianjinAges 20–80 - NCT06035887Recruiting
New eye test for hydroxychloroquine damage
This trial tests a new type of eye test (ERG) to detect early damage from hydroxychloroquine, a drug used for conditions like lupus and rheumatoid arthritis. If you take hydroxychloroquine or have never taken it, you might help find better ways to protect your vision.
London, LondonAges 18 years+ - NCT07235085RecruitingPhase 3
Study of OTX-TKI implant for moderate to severe NPDR
This study tests an eye implant (OTX-TKI) that slowly releases a medicine to slow or stop worsening of non-proliferative diabetic retinopathy (NPDR) — an early form of diabetic eye disease. It's for people with moderately severe to severe NPDR who haven't had significant treatments like laser or injections in that eye.
Hagerstown, MarylandAges 18 years+ - NCT06269419Recruiting
Diabetes eye disease natural progression study
This study follows people with type 2 diabetes to understand how diabetic retinopathy (an eye disease caused by diabetes) changes over time without treatment. It may help if you have no other eye issues causing new blood vessels and are not planning for certain eye procedures.
Chengdu, SichuanAges 18–75 - NCT07747428Recruiting
Eye imaging study for diabetic retinopathy
This study uses a special eye imaging test called OCT angiography to look at tiny blood vessels in the back of the eye. It aims to understand changes caused by diabetic retinopathy, which could help improve how we monitor and treat this condition.
SohagAges 18–80 - NCT05296447Enrolling by invitationPhase 2
Long-term safety study for diabetic retinopathy gene therapy
This study follows people who already received an injection of RGX-314 (an experimental gene therapy) in a previous clinical trial for diabetic retinopathy, with or without swelling in the macula. It checks the long-term safety and how the treatment works over time.
Phoenix, ArizonaAges Any age - NCT05079399Recruiting
Diabetic eye screening study using eye scans
This study looks for specific eye findings (“biomarkers”) in people with type 2 diabetes using eye imaging. It may help researchers better understand diabetic retinopathy and how to detect it earlier or more accurately.
Carmel, IndianaAges 18 years+ - NCT00346814RecruitingPhase 2/Phase 3
Bevacizumab injections for severe eye vessel disease in premature babies
This trial studies whether an anti–blood vessel medicine (bevacizumab, given by eye injection) can improve the structure of the retina in very premature babies with advanced retinopathy of prematurity. It may help when standard treatments like laser or freezing cannot be used.
Mexico City, Mexico DFAges 1 month–1 year - NCT03083431RecruitingPhase 2
Oral propranolol to prevent early retinopathy in preemies
This trial tests whether giving propranolol by mouth to certain very premature babies with early eye changes can stop retinopathy of prematurity from getting worse. It may help reduce the need for eye treatments later on.
Tübingen, Baden-WurttembergAges 1 month–3 months - NCT03403686Recruiting
Study eye treatment target for diabetic retinopathy
This study tests a new approach aimed at improving diabetic eye disease (diabetic retinopathy). It may help by changing inflammation and related processes in the eye, especially in people who have diabetes and eye changes.
Birmingham, AlabamaAges 21–98 - NCT03403699Recruiting
Stem cell treatment for damaged eye blood vessels in diabetes
This study tests human iPSC–derived (lab-grown) cells aimed at repairing fragile, damaged blood vessels in diabetic retinopathy. It also involves eye exams and a small skin biopsy to support the research.
Birmingham, AlabamaAges 21–98 - NCT03542734Recruiting
Imaging study for thinking and brain changes in older adults
This study looks at brain scans and eye/eye-nerve findings to understand why thinking can change with aging. It may help researchers connect eye and brain changes, which could guide future ways to prevent or detect dementia early.
HangzhouAges 40 years+
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Common questions
- Are there clinical trials for retinopathy?
- Yes. Clin2 currently lists 116 recruiting retinopathy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a retinopathy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a retinopathy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.