Clinical trials
Retreatment clinical trials
Below are recruiting retreatment clinical trials, each written for real people, not researchers. We’re tracking 25 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07056998Enrolling by invitation
AI detects root canal quality, then retreats if needed
This trial tests whether artificial intelligence can spot problems in root canal treatments seen on special X-rays (CBCT) compared to regular X-rays. If the AI finds an issue, a retreatment is done.
Cairo, Cairo GovernorateAges 18–50 - NCT05773274RecruitingPhase 2
Retreating with 177Lu-DOTATATE radiation versus usual treatment
This trial tests whether repeating a targeted radioactive treatment (177Lu-DOTATATE) works better than standard options in people with metastatic gastroenteropancreatic neuroendocrine tumors. It may help by controlling tumor growth after the first round of this therapy stops working.
Birmingham, AlabamaAges 18 years+ - NCT07194837Recruiting
Laser treatment for root canal retreatment healing
This trial tests whether a special laser (810 nm diode) can help heal infections around the root tip after a failed root canal. It is for people who have a single-rooted tooth that needs retreatment.
CairoAges 20–45 - NCT04527705Recruiting
Testing endodontic retreatment in one versus two visits
This study compares doing tooth root-canal retreatment in one visit versus two visits. It’s meant to see which approach leads to better outcomes for teeth with infection at the root tip (apical periodontitis).
Sant Cugat del Vallès, BarcelonaAges 18–75 - NCT07429617Recruiting
Darkness retreat study for healthy adults
This study explores the effects of spending time in complete darkness. You might join if you are generally healthy, not taking any mental health medication, and not currently in therapy.
Poznan, WielkopolskaAges 30–50 - NCT07448571Recruiting
Testing i-PRF for better root canal retreatment healing
This study tests whether using a special platelet-rich concentrate (i-PRF) during a root canal retreatment can help heal infection at the tip of the root better than standard retreatment alone. It is for adults with a previously treated upper front tooth that now shows signs of infection on X-ray.
IstanbulAges 18–50 - NCT07641933RecruitingPhase 1
Root Canal Retreatment Dressing Comparison Study
This study compares different medicines placed inside root canals between appointments to help heal infections. You'll have a tooth retreated (cleaned and filled again) and help researchers find which dressing works best.
CairoAges 21–45 - NCT07566286Recruiting
Safety Study of Restylane Lyft for Chin Enhancement
This study tests the safety of a dermal filler (Restylane Lyft) used to enhance and reshape the chin. If you're interested in chin augmentation, this trial may help you receive the treatment while contributing to safety data.
Westport, ConnecticutAges 22 years+ - NCT04143516RecruitingPhase 2/Phase 3
Test tissue testing right after liver tumor ablation
This study looks at liver metastases treated with a procedure that destroys tumors (ablation) and then checks tumor tissue right away. The team wants to see whether the tissue results can guide immediate retreatment to better control cancer in the liver.
New York, New YorkAges 18 years+ - NCT07077694Enrolling by invitation
AI study to find missed root canals in treated lower back teeth
This study uses artificial intelligence and 3D dental imaging to check if any root canals were missed during previous root canal treatment on lower back teeth. It may help find hidden problems and guide better treatment.
Cairo, Cairo GovernorateAges 18–50 - NCT07298018Recruiting
RISE retreat for nurse managers with burnout
This study tests a retreat program called RISE that is designed to help Nurse Managers at AdventHealth reduce burnout. If you are experiencing moderate to high levels of emotional exhaustion or depersonalization, this program may offer support.
Orlando, FloridaAges 18 years+ - NCT04523428RecruitingPhase 2
Second round of targeted pills after short venetoclax benefit
This trial studies whether repeating two targeted medicines—venetoclax plus acalabrutinib—for a limited time can control CLL or SLL after you had a partial response to earlier venetoclax-based treatment. It may help people who need retreatment but want another approach beyond the first limited course.
BrusselsAges 18 years+ - NCT07141459Recruiting
Laser disinfection for failed root canal treatment
This trial tests if using a special laser (810 nm diode) to disinfect the tooth after a second root canal treatment can reduce pain and inflammation. It aims to help patients whose previous root canal failed and who have a small infection around the tooth root.
CairoAges 20–40 - NCT04260477RecruitingPhase 3
Testing a new stronger TB retreatment medicine schedule
This trial tests a new “triple-dose” set of medicines to treat people whose tuberculosis (TB) has come back in the lungs. If you qualify, the goal is to improve cure rates and reduce the chance of TB returning again.
NiameyAges Any age - NCT04528979Recruiting
Tests a bioceramic filling material for root-canal treatment outcomes
This study looks at how well a bioceramic sealing material works for tooth root-canal treatment, including cases where previous treatment did not work. If you have certain types of tooth nerve inflammation or infection, you may be eligible to help compare outcomes and improve care.
Sant Cugat del Vallès, BarcelonaAges 18–75 - NCT04656184RecruitingPhase 3
Anakinra vs IVIG for kids who don’t respond to first IVIG
This study compares two treatments—anakinra and IVIG—for children with Kawasaki disease who still have fever after their first standard IVIG treatment. It aims to find which option works better and is safer for “IVIG non-responders” who may be at risk for heart complications.
Le Kremlin-Bicêtre, Val De MarneAges 3 months–17 years - NCT04954820RecruitingPhase 2
Second round Lutathera for intestinal NET after regrowth
This Phase 2 study looks at whether giving Lutathera again (a second round) can control an intestinal neuroendocrine tumor (NET) that came back or progressed after the first treatment. It mainly targets adults whose scan shows tumors still take up the right “target” signal and who previously benefited for at least 12 months.
AngersAges 18 years+ - NCT05460507RecruitingPhase 1
Re-treating brain tumor with radioactive liposome after prior dose
This Phase 1 trial tests whether a radioactive treatment delivered in tiny fat “packets” is safe and tolerable when given again to people whose glioma (brain tumor) came back after a previous similar treatment. It also looks at how well this re-treatment works in carefully selected patients.
San Antonio, TexasAges 18 years+ - NCT06538480RecruitingPhase 4
Zopa retreatment study for recurrent respiratory papillomatosis
This trial tests if people with recurrent respiratory papillomatosis (growths in the airway caused by HPV) can safely get more doses of the study drug Zopa and checks if the virus spreads after treatment. It may help people who have already tried Zopa or are considering it for the first time.
Atlanta, GeorgiaAges 18 years+ - NCT06729814Recruiting
Repeated Breast Radiation Side Effects Study
This study asks whether having radiation therapy again to the same breast or chest (15 sessions over 3 weeks) causes more skin redness, peeling, or pain. The goal is to learn more about side effects so doctors can better prepare and support patients who need a second course of breast radiation.
Toronto, OntarioAges 18 years+ - NCT07453576Recruiting
Comparing bleach strengths for root canal retreatment pain
This trial tests if different concentrations of sodium hypochlorite (a disinfectant used in root canals) affect pain and certain natural chemicals in the tooth during root canal retreatment. It may help find the best option to reduce discomfort.
Erzurum, ErzurumAges 18–65 - NCT07505082Recruiting
Repeat Nectero EAST treatment for abdominal aortic aneurysm
This trial is for people who have already had a Nectero EAST treatment for their abdominal aortic aneurysm and need a repeat procedure. It checks how well a second treatment works and if it is safe.
Randwick, New South WalesAges 21–85 - NCT07536113Recruiting
Blood Test to Guide Second Colorectal Cancer Treatment
This study looks at whether a simple blood test can help doctors decide if you should receive a specific type of cancer drug again. The blood test looks for cancer DNA to predict if the drug will work for your advanced colorectal cancer.
Milan, ItaliaAges 18 years+ - NCT07599254RecruitingPhase 4
Pain Relief After Root Canal Retreatment
This study tests two different ways of cleaning and treating a tooth that had a root canal treatment before. Researchers want to see which method causes less pain after the procedure.
KayseriAges 18–60
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Common questions
- Are there clinical trials for retreatment?
- Yes. Clin2 currently lists 25 recruiting retreatment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a retreatment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a retreatment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.