Clinical trials
Safety and Effectiveness clinical trials
Below are recruiting safety and effectiveness clinical trials, each written for real people, not researchers. We’re tracking 386 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07774598Recruiting
Non-invasive nerve stimulation for essential tremor
This trial is testing whether a device that gently stimulates the nerves in your arm (called non-invasive neuromodulation) can safely reduce hand tremors over a long period. It might help with activities like eating, writing, or dressing.
ShanghaiAges 18–75 - NCT07762872Recruiting
Satralizumab during early NMOSD attacks
This study looks at how well the medication satralizumab works when started early during an NMOSD attack, along with standard treatments. The aim is to see if adding this drug can help reduce the impact of the attack and improve outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07746895RecruitingPhase 4
Study of pegcetacoplan for C3G or IC-MPGN kidney disease
This study looks at how well pegcetacoplan works and how safe it is for people with two rare kidney diseases, called C3G and IC-MPGN. It will help doctors understand how the medicine helps patients in real life, outside of a strict clinical trial.
KingswoodAges Any age - NCT06625749Recruiting
AccuraSee lens implant to improve near vision after cataract surgery
This trial tests an artificial lens (AccuraSee IOPCL) placed inside your eye to help you see better up close and at intermediate distances after having cataract surgery. It is for people who still need reading glasses and have a specific type of monofocal lens already in their eye.
Cleveland, OhioAges 22 years+ - NCT07724587Recruiting
Exercise study for muscle wasting in dialysis patients
This trial tests if a supervised exercise program can help people on dialysis who have muscle wasting (uremic sarcopenia). It aims to improve muscle strength, physical function, and quality of life.
NingboAges 18–80 - NCT07724873RecruitingPhase 1/Phase 2
Withaferin A to prevent GVHD after stem cell transplant
This study tests a natural compound called Withaferin A (from ashwagandha) to see if it helps prevent graft-versus-host disease (GVHD) after a stem cell transplant. The goal is to reduce the risk of transplant complications.
Navi Mumbai, MaharashtraAges 18 years+ - NCT07716475Recruiting
Home gait training with a hip robot for stroke recovery
This trial tests a wearable hip robot to help people with stroke walk better at home. It may improve your gait and daily movement.
Yongin-si, Gyeonggi-doAges 19–80 - NCT07710443Recruiting
Mosaic Filler Trial for Midface Volume Loss
This trial tests a new cheek filler called Mosaic for people with moderate to severe cheek volume loss. It helps doctors see if Mosaic is safe and effective for filling out the midface area.
Bradenton, FloridaAges 22 years+ - NCT07706764RecruitingPhase 3
Testing a new treatment for teens with long-term hypoparathyroidism
This study tests a new medicine called palopegteriparatide for teenagers with long-term hypoparathyroidism (low parathyroid hormone). The medicine is given as a daily injection and aims to help control calcium levels.
BronAges 12–18 - NCT06594289Recruiting
Liver surgery trial with special blood flow control
This trial tests a new way to control blood flow during laparoscopic liver surgery. It compares two methods to see which is safer and more effective for patients with certain liver conditions.
Guangzhou, China/GuangdongAges 18–70 - NCT07694921Enrolling by invitation
Non-invasive brain stimulation for Alzheimer's disease
This trial tests if a safe, non-invasive electrical stimulation can help people with Alzheimer's disease. It aims to improve thinking and memory skills.
Hangzhou, ZhejiangAges 60 years+ - NCT07688213RecruitingPhase 2
Study of an investigational drug for early Alzheimer's disease
This trial tests an investigational injection for people in the early stages of Alzheimer's. It aims to see if the drug can safely slow down memory loss and brain changes.
Oakland, CaliforniaAges 55–85 - NCT07675304RecruitingEarly Phase 1
Mesotherapy for chronic low back pain study
This trial tests whether injecting a natural substance (collagen) into the lower back can safely reduce chronic pain. It may help people with pain that hasn't spread to the legs.
WarsawAges 18–65 - NCT07678268RecruitingPhase 4
Comparing HIV treatments for virologically suppressed men
This trial tests if a two-drug HIV regimen (darunavir/cobicistat plus lamivudine) works as well as a three-drug regimen (darunavir/cobicistat plus tenofovir alafenamide/emtricitabine) in men whose HIV is already suppressed. The goal is to find a simpler, effective option that may have fewer side effects.
Mexico City, Mexico CityAges 18 years+ - NCT07675070Recruiting
Temozolomide (Amitzo) for grade III or IV brain tumors
This trial studies a new form of the chemotherapy drug temozolomide (called Amitzo) in people with aggressive brain tumors (grade III or IV gliomas). It aims to see if the drug is safe and effective, and is for patients who need treatment for a new diagnosis or for tumors that have come back after standard care.
TehranAges 18–80 - NCT07677696Recruiting
Study of midline catheters for first-time placement
This trial is testing how well a midline catheter works for people who need one for the first time. It will help doctors understand if this type of IV line is a good option for delivering medication or fluids.
ZiboAges 18 years+ - NCT07668804RecruitingPhase 1/Phase 2
Study of an eye implant for geographic atrophy from dry AMD
This trial is testing a new eye implant (TO-O-1007) to see if it's safe and helps slow vision loss from geographic atrophy, a late stage of dry age-related macular degeneration (AMD). The implant is placed inside the eye and releases medicine over time.
Hurstville, New South Wales (nsw)Ages 50 years+ - NCT06258668Recruiting
Real-world study of Sotyktu for psoriasis in Korea
This study looks at how safe and effective a pill called Sotyktu is for people with moderate-to-severe plaque psoriasis in real-life medical settings in Korea. If you are 19 or older and are about to start Sotyktu for your psoriasis as your doctor prescribes, this study may be an option for you.
SeoulAges 19 years+ - NCT07659418Recruiting
Vitiligo medication safety registry for adults and teens
This registry tracks the safety and effectiveness of vitiligo medications over time. It helps doctors learn how well treatments work for adults and teens with nonsegmental vitiligo.
Waltham, MassachusettsAges 12 years+ - NCT07662330Recruiting
Spermidine for weight and cholesterol in overweight adults
This trial tests if a natural supplement called spermidine can help lower cholesterol and body weight in overweight people with high cholesterol. You cannot be on any cholesterol or diabetes medications.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT03918408RecruitingPhase 1
Platinum eye drops and light to slow keratoconus
This Phase 1 study tests whether a specific corneal cross-linking system (called PXL-Platinum 330) is safe and effective for people with progressive keratoconus, a condition that makes the cornea thin and bulge. The goal is to slow vision changes and see how well the treatment works in the short term.
Eugene, OregonAges 12–45 - NCT07648693Recruiting
Brain Protection Device During Aortic Valve Replacement
This trial tests a new device called CHORDS that protects your brain during transcatheter aortic valve replacement (TAVR), a minimally invasive procedure to fix a narrow aortic valve. The device works by blocking debris that might travel to your brain during the procedure.
Bengbu, AnhuiAges 18 years+ - NCT07654829RecruitingPhase 4
Sebetralstat to prevent swelling before procedures in HAE
This trial tests if sebetralstat can prevent swelling attacks before medical procedures in people with HAE types I or II. You take the medicine short-term before your procedure to see if it helps protect you from an attack.
Colorado Springs, ColoradoAges 12 years+ - NCT06543758RecruitingPhase 4
Gait rehab with a wearable robot at home
This trial tests whether using a wearable robotic device at home can improve walking ability in people who have had a stroke. If you have trouble walking due to a stroke, this study may help you regain strength and mobility.
Yongin-si, Gyeonggi-doAges 19–79
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Common questions
- Are there clinical trials for safety and effectiveness?
- Yes. Clin2 currently lists 386 recruiting safety and effectiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a safety and effectiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a safety and effectiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.