Clinical trials
Sepsis and Septic Shock clinical trials
Below are recruiting sepsis and septic shock clinical trials, each written for real people, not researchers. We’re tracking 92 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07136532Recruiting
Predicting fluid needs in children with septic shock using ultrasound
This study tests whether using ultrasound of the neck (carotid artery) and heart can help doctors know which children with septic shock need more fluids. It aims to make fluid treatment safer and more precise in the pediatric intensive care unit (PICU).
CairoAges 1 month–16 years - NCT05057611Recruiting
Tested blood-pressure rescue strategy using skin refill time
This study looks at a specific resuscitation (rescue) approach for adults in septic shock, using a bedside skin test called capillary refill time. If you qualify, the goal is to see whether this approach better stabilizes your body and improves outcomes.
Santiago, Santiago MetropolitanAges 18 years+ - NCT07286643Recruiting
Ultrasound-guided sepsis care for patients with cirrhosis
This study tests whether using a special ultrasound of the heart can guide treatment for sepsis-related low blood pressure in patients with cirrhosis. It aims to improve care and outcomes for critically ill patients.
ChandigarhAges 18–65 - NCT07264543RecruitingPhase 2/Phase 3
Early methylene blue for blood flow in sepsis
This trial tests if giving methylene blue early can improve blood flow in patients with sepsis who still have low blood pressure despite fluids and are on high doses of noradrenaline. It aims to help stabilize their condition.
Curitiba, ParanáAges 18 years+ - NCT05442710RecruitingPhase 2
Immune cell treatment for recovery from severe septic shock
This trial tests an immune-cell treatment given outside the body to help people recover from septic shock, a life-threatening reaction to infection. It aims to improve survival and organ recovery in patients who are still very ill despite standard care.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT04931225RecruitingPhase 3
Landiolol for heart-rate and circulation problems in septic shock
This Phase 3 trial tests whether landiolol (a short-acting heart-rate–lowering medicine) can improve blood circulation in adults with septic shock whose heart rate is too fast. Doctors will also check that the medication is safe in this critical-care setting.
ParisAges 18 years+ - NCT06723626Recruiting
Recovery blend for elderly sepsis patients
This study tests whether giving a special combination of hydrocortisone, vitamin C, and vitamin B1 helps older adults with sepsis recover better. It looks at how the treatment affects tiny blood vessels and overall survival.
Nanjing, JiangsuAges 60–85 - NCT06440317Recruiting
Study of a special filter for kidney dialysis in septic shock
This trial tests whether a special type of dialysis filter (oXiris) helps reduce blood clotting problems in patients with septic shock and kidney failure. It may offer a better option for those needing kidney support in the ICU.
PessacAges 18 years+ - NCT06749756Recruiting
Vitamins B6, B12 and C for sepsis
This trial tests whether a combination of vitamins B6, B12, and C can help improve blood flow in tiny blood vessels (microcirculation) for people with sepsis. It may help your body recover better from severe infection.
Chengdu, SichuanAges 18–85 - NCT05146336Recruiting
CytoSorb registry for critically ill patients needing blood treatment
This registry collects information about critically ill patients who receive the CytoSorb 300 mL blood treatment. It may help doctors better understand when the treatment works best and when it should not be used.
KlagenfurtAges Any age - NCT06143137Recruiting
Long-term recovery after septic shock treatment
This study checks on people who had septic shock and were in the ReActIF-ICE trial. It looks at how their immune system recovered over time after an experimental therapy.
MagdeburgAges 18–80 - NCT05575024Recruiting
Monitoring blood pressure and heart rhythm during kidney support in sepsis
This study looks at how stable blood pressure and heart rhythm are in people with sepsis who need continuous kidney filtration. If you qualify, it may help researchers better improve care for critically ill patients receiving this treatment.
SeoulAges 18 years+ - NCT06492044Recruiting
Testing right heart strain to predict fluid response in septic shock
This study tests whether measuring the strain (stretch) of the right upper heart chamber with ultrasound can predict if a patient with septic shock will benefit from more fluids. Septic shock is a severe infection that causes very low blood pressure and organ damage.
AmiensAges 18 years+ - NCT06370078Recruiting
Albumin 20% vs Standard Fluids for Septic Shock
This trial tests whether giving a concentrated protein solution (albumin 20%) early in septic shock helps better than standard fluids (crystalloids). It's for people who have been in septic shock less than 24 hours and still need blood pressure support.
AsyutAges 18–60 - NCT07530146RecruitingPhase 3
Sedation Medications for Older ICU Patients on Breathing Machines
This study compares two sedation medications—propofol alone versus propofol combined with ketamine—in older patients in the ICU who are on breathing machines due to infection or lung problems. The goal is to find which combination is safer and works better for keeping patients calm and comfortable.
CairoAges 65 years+ - NCT07682766Recruiting
Biomarkers of inflammation and infection in critical care
This study looks at markers of inflammation, infection, and immunity in patients who are in the critical care area. It aims to find early signs of how severe the illness might become, how well treatments work, and if infections will develop.
TorinoAges 18 years+ - NCT07411469Recruiting
Comparing heart monitoring methods in sepsis patients
This study compares two methods to measure fluid responsiveness in patients with sepsis and hypotension: cardiometry (non-invasive heart monitoring) and ultrasound of the IVC vein. The goal is to find a simpler way to guide treatment.
Shibīn al Kawm, MenoufiaAges 18–65 - NCT05692011Recruiting
Testing a blood-filter treatment in children with early sepsis
This trial looks at whether a blood-filter treatment (called “AN69ST Verse PS” using a hemofilter) can help children with early, serious sepsis and poor circulation or organ problems. It may help stabilize the body faster, but eligibility is limited to certain sepsis situations and recent timing.
Shanghai, Shanghai MunicipalityAges 4 weeks–28 years - NCT05044403Recruiting
Hemoperfusion for severe sepsis causing multiple organ failure
This study tests whether a blood-filter treatment called hemoperfusion can help critically ill people with sepsis that is not responding to standard shock treatment and is affecting multiple organs. It aims to improve recovery when infections are controlled and inflammation markers are very high.
Castellon, CastellónAges 18–80
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Common questions
- Are there clinical trials for sepsis and septic shock?
- Yes. Clin2 currently lists 92 recruiting sepsis and septic shock studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sepsis and septic shock trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sepsis and septic shock trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.