Clinical trials
Severe Pneumonia clinical trials
Below are recruiting severe pneumonia clinical trials, each written for real people, not researchers. We’re tracking 28 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06514781Recruiting
Comparing sedation methods for severe pneumonia in the ICU
This study looks at different ways to sedate patients on a breathing machine in the ICU who have severe pneumonia. The goal is to find which approach works best for recovery and comfort.
Changsha, HunanAges 18 years+ - NCT07113951Enrolling by invitation
AI-ROSE for diagnosing severe pneumonia
This trial uses an AI tool called AI-ROSE to analyze lung fluid from a bronchoscopy. It aims to help doctors quickly diagnose severe pneumonia and guide treatment.
Nanjing, JiangsuAges 18 years+ - NCT06693362RecruitingPhase 1
Stem cell therapy for severe viral pneumonia
This trial tests whether injecting stem cells from the womb's blood supply can help treat severe viral pneumonia. It aims to improve recovery for people who are very sick and need hospital care.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06114784Recruiting
Study of microbiome and severe pneumonia with breathing support
This study looks at how bacteria in your body (microbiome) affect how sick you get from severe pneumonia. It may help doctors find better ways to treat people with serious lung infections who need breathing support.
Hangzhou, ZhejiangAges 18 years+ - NCT06516601Recruiting
Severe community-acquired pneumonia observational study
This study looks at patients with severe pneumonia caught outside the hospital. Researchers will review medical records to learn more about how this serious infection progresses.
Trieste, TSAges 18 years+ - NCT07615010RecruitingPhase 2
agenT-797 Plus Standard Care for Severe Pneumonia With Respiratory Failure
This trial tests whether adding an experimental drug called agenT-797 to standard pneumonia treatment helps patients in the ICU who have severe pneumonia and serious difficulty breathing (acute hypoxemic respiratory failure). The drug is designed to help the immune system fight severe infection.
San Francisco, CaliforniaAges 18 years+ - NCT07070284Enrolling by invitation
Severe pneumonia in older adults: a study of risks and outcomes
This study looks at older adults with severe pneumonia to understand what causes it and how to improve outcomes. If you are 65 or older and have severe pneumonia, this trial may help doctors learn more about your condition.
Zagreb, City of ZagrebAges 65 years+ - NCT07206745Recruiting
Chinese and Western medicine for severe pneumonia from drug-resistant bacteria
This trial tests a combination of traditional Chinese and Western medicine for adults with severe pneumonia caused by bacteria that are resistant to multiple antibiotics. It aims to see if this combined approach can improve treatment outcomes.
Zhengzhou, HenanAges 18–80 - NCT05842382RecruitingPhase 2
High-dose IV vitamin C for severe pneumonia
This trial tests whether high-dose vitamin C given through an IV can improve outcomes in people with severe pneumonia. It may help your body fight infection and reduce complications, but it also has several safety checks.
Alor Star, KedahAges 18 years+ - NCT07414693RecruitingPhase 4
Vitamin C for kids with severe pneumonia
This trial tests if giving vitamin C to children hospitalized with severe pneumonia can help them get better faster and leave the hospital sooner. It may be an option for children who have had pneumonia symptoms for 48 hours or less.
Multan Khurd, Punjab ProvinceAges 2 months–4.9 years - NCT06137196Recruiting
Lung function risks after severe pneumonia in AIDS patients
This study looks at why some people with AIDS who recover from severe pneumonia later have trouble breathing. Researchers want to find risk factors so they can help prevent lung damage.
Guangzhou, GuangdongAges 18–65 - NCT06145828Recruiting
Testing a blood filter for severe pneumonia or sepsis in AIDS patients
This study tests a technique that filters harmful substances from the blood of people with AIDS who have severe pneumonia or septic shock. The goal is to see if this filter helps them recover better.
Guangzhou, GuangdongAges 18–65 - NCT03031210RecruitingPhase 2/Phase 3
Twice-daily amoxicillin for mild childhood pneumonia
This trial tests whether twice-daily amoxicillin helps treat non-severe pneumonia in children. It may be a good option if your child has a mild form confirmed by symptoms and a chest X-ray.
Montreal, QuebecAges 3 months–18 years - NCT01068990Recruiting
Testing how to identify pneumonia germs in ICU patients
This study looks at how well doctors can detect and identify the cause of new pneumonia in people in the medical intensive care unit (ICU). It may help improve how pneumonia is diagnosed and treated in critically ill patients.
SeoulAges 16 years+ - NCT05688774Recruiting
Study of worsening community pneumonia in people with weaker immunity
This study follows how community-acquired pneumonia progresses in hospitalized patients who already have serious health problems or weakened immune systems. The goal is to better understand risk and changes over time, which may help guide future care for people like you.
BerlinAges 18–99 - NCT05903352RecruitingPhase 3
Personalized antibiotic duration for hospital pneumonia patients
This trial compares how long antibiotics should be given to people hospitalized with moderately severe community-acquired pneumonia. It uses your early improvement to see which antibiotic duration works best and safely.
GarchesAges 18 years+ - NCT06743529Recruiting
Immediate or watchful waiting for antibiotics in possible pneumonia
This trial compares starting antibiotics right away versus waiting for more test results in people on a breathing machine who may have pneumonia. The goal is to find out which approach works better without causing harm.
Angers, FranceAges 18 years+ - NCT05722938RecruitingPhase 3
Testing Trimodulin for severe pneumonia on breathing support
This trial tests an investigational medicine called Trimodulin (BT588) for people with severe pneumonia who need a breathing machine. The goal is to see if it helps them recover faster.
Mobile, AlabamaAges 18 years+ - NCT06269900RecruitingPhase 3
Dexamethasone for Severe Hospital-Acquired Pneumonia with Inflammation
This trial tests whether adding the anti-inflammatory drug dexamethasone to standard antibiotics improves recovery from severe hospital-acquired pneumonia in critically ill patients on a ventilator.
AmiensAges 18–85 - NCT05181696Recruiting
Study of chest X-ray severity scores in ICU COVID-19 pneumonia
This study reviews past chest X-rays from people who were hospitalized in the ICU for COVID-19 pneumonia caused by SARS-CoV-2. It aims to see how well a chest X-ray severity scoring system reflects how sick the lungs were.
OsijekAges 18–90 - NCT04178915Enrolling by invitation
Blood marker study to predict severe bacterial lung infection
This study looks at specific immune cells and how fats are transported in the blood to predict which people will have a severe bacterial infection (like pneumonia or sepsis). Your results may help doctors identify higher-risk patients earlier.
MinskAges 18–60 - NCT06477861Recruiting
Elastic power predicts ARDS severity and death risk
This study looks at a new way to predict how serious ARDS (a severe lung injury from pneumonia) is and the chance of death. Doctors will measure something called "elastic power" to see if it helps guide treatment for patients on a breathing machine.
Banhā, Al QalubeyahAges 18–65 - NCT07004049RecruitingPhase 4
Testing combinations for resistant Gram-negative infections
This study tests different antibiotic combinations for severe infections caused by hard-to-treat Gram-negative bacteria (like Pseudomonas or Acinetobacter). The goal is to find the best treatment for bloodstream infections or pneumonia that started in the hospital.
Brisbane, QueenslandAges 18 years+ - NCT03044223Recruiting
Profiles of immune cells in severe Pseudomonas sepsis
This study looks at patterns of immune cells in people who are critically ill with sepsis caused by Pseudomonas aeruginosa bacteria. It may help doctors better understand how the immune system responds and improve care for this serious infection.
UlmAges 18–90
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Common questions
- Are there clinical trials for severe pneumonia?
- Yes. Clin2 currently lists 28 recruiting severe pneumonia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a severe pneumonia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a severe pneumonia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.