Clinical trials
Severe Pneumonia clinical trials
Below are recruiting severe pneumonia clinical trials, each written for real people, not researchers. We’re tracking 24 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07113951Enrolling by invitation
AI-ROSE for diagnosing severe pneumonia
This trial uses an AI tool called AI-ROSE to analyze lung fluid from a bronchoscopy. It aims to help doctors quickly diagnose severe pneumonia and guide treatment.
Nanjing, JiangsuAges 18 years+ - NCT06693362RecruitingPhase 1
Stem cell therapy for severe viral pneumonia
This trial tests whether injecting stem cells from the womb's blood supply can help treat severe viral pneumonia. It aims to improve recovery for people who are very sick and need hospital care.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06114784Recruiting
Study of microbiome and severe pneumonia with breathing support
This study looks at how bacteria in your body (microbiome) affect how sick you get from severe pneumonia. It may help doctors find better ways to treat people with serious lung infections who need breathing support.
Hangzhou, ZhejiangAges 18 years+ - NCT07615010RecruitingPhase 2
agenT-797 Plus Standard Care for Severe Pneumonia With Respiratory Failure
This trial tests whether adding an experimental drug called agenT-797 to standard pneumonia treatment helps patients in the ICU who have severe pneumonia and serious difficulty breathing (acute hypoxemic respiratory failure). The drug is designed to help the immune system fight severe infection.
San Francisco, CaliforniaAges 18 years+ - NCT07070284Enrolling by invitation
Severe pneumonia in older adults: a study of risks and outcomes
This study looks at older adults with severe pneumonia to understand what causes it and how to improve outcomes. If you are 65 or older and have severe pneumonia, this trial may help doctors learn more about your condition.
Zagreb, City of ZagrebAges 65 years+ - NCT07206745Recruiting
Chinese and Western medicine for severe pneumonia from drug-resistant bacteria
This trial tests a combination of traditional Chinese and Western medicine for adults with severe pneumonia caused by bacteria that are resistant to multiple antibiotics. It aims to see if this combined approach can improve treatment outcomes.
Zhengzhou, HenanAges 18–80 - NCT07414693RecruitingPhase 4
Vitamin C for kids with severe pneumonia
This trial tests if giving vitamin C to children hospitalized with severe pneumonia can help them get better faster and leave the hospital sooner. It may be an option for children who have had pneumonia symptoms for 48 hours or less.
Multan Khurd, Punjab ProvinceAges 2 months–4.9 years - NCT06137196Recruiting
Lung function risks after severe pneumonia in AIDS patients
This study looks at why some people with AIDS who recover from severe pneumonia later have trouble breathing. Researchers want to find risk factors so they can help prevent lung damage.
Guangzhou, GuangdongAges 18–65 - NCT06145828Recruiting
Testing a blood filter for severe pneumonia or sepsis in AIDS patients
This study tests a technique that filters harmful substances from the blood of people with AIDS who have severe pneumonia or septic shock. The goal is to see if this filter helps them recover better.
Guangzhou, GuangdongAges 18–65 - NCT03031210RecruitingPhase 2/Phase 3
Twice-daily amoxicillin for mild childhood pneumonia
This trial tests whether twice-daily amoxicillin helps treat non-severe pneumonia in children. It may be a good option if your child has a mild form confirmed by symptoms and a chest X-ray.
Montreal, QuebecAges 3 months–18 years - NCT01068990Recruiting
Testing how to identify pneumonia germs in ICU patients
This study looks at how well doctors can detect and identify the cause of new pneumonia in people in the medical intensive care unit (ICU). It may help improve how pneumonia is diagnosed and treated in critically ill patients.
SeoulAges 16 years+ - NCT05688774Recruiting
Study of worsening community pneumonia in people with weaker immunity
This study follows how community-acquired pneumonia progresses in hospitalized patients who already have serious health problems or weakened immune systems. The goal is to better understand risk and changes over time, which may help guide future care for people like you.
BerlinAges 18–99 - NCT05903352RecruitingPhase 3
Personalized antibiotic duration for hospital pneumonia patients
This trial compares how long antibiotics should be given to people hospitalized with moderately severe community-acquired pneumonia. It uses your early improvement to see which antibiotic duration works best and safely.
GarchesAges 18 years+ - NCT06743529Recruiting
Antibiotics right away or later for lung infections from a breathing machine
This study looks at when to start antibiotics for a lung infection you may have gotten while on a breathing machine. It compares starting them right away versus waiting for the test results to be sure you need them.
Angers, FranceAges 18 years+ - NCT05722938RecruitingPhase 3
Testing Trimodulin for severe pneumonia on breathing support
This trial tests an investigational medicine called Trimodulin (BT588) for people with severe pneumonia who need a breathing machine. The goal is to see if it helps them recover faster.
Mobile, AlabamaAges 18 years+ - NCT06269900RecruitingPhase 3
Dexamethasone for Severe Hospital-Acquired Pneumonia with Inflammation
This trial tests whether adding the anti-inflammatory drug dexamethasone to standard antibiotics improves recovery from severe hospital-acquired pneumonia in critically ill patients on a ventilator.
AmiensAges 18–85 - NCT04178915Enrolling by invitation
Blood marker study to predict severe bacterial lung infection
This study looks at specific immune cells and how fats are transported in the blood to predict which people will have a severe bacterial infection (like pneumonia or sepsis). Your results may help doctors identify higher-risk patients earlier.
MinskAges 18–60 - NCT07004049RecruitingPhase 4
Testing combinations for resistant Gram-negative infections
This study tests different antibiotic combinations for severe infections caused by hard-to-treat Gram-negative bacteria (like Pseudomonas or Acinetobacter). The goal is to find the best treatment for bloodstream infections or pneumonia that started in the hospital.
Brisbane, QueenslandAges 18 years+ - NCT06817421RecruitingPhase 4
Pneumococcal vaccine for children with severe malnutrition
This study tests whether giving the pneumococcal vaccine during hospitalization for severe malnutrition can help prevent infections. It may help protect your child from serious illness.
DiliAges 6 months–4.9 years - NCT03044223Recruiting
Profiles of immune cells in severe Pseudomonas sepsis
This study looks at patterns of immune cells in people who are critically ill with sepsis caused by Pseudomonas aeruginosa bacteria. It may help doctors better understand how the immune system responds and improve care for this serious infection.
UlmAges 18–90 - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT06069115Recruiting
How radiation affects lung function in breast cancer patients
This study looks at how radiation therapy for breast cancer may affect your lungs over time. Researchers will measure lung function and see if problems develop, so they can better understand and protect patients.
Novosibirsk, Novosibirsk OblastAges 18 years+ - NCT07358910Recruiting
Tracking infectious diseases in communities
This study looks at how infections spread in villages in Cambodia. If you live in a participating village, you might help us understand and prevent disease outbreaks.
Phnom Penh, Phnom PenhAges 2–75
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Common questions
- Are there clinical trials for severe pneumonia?
- Yes. Clin2 currently lists 24 recruiting severe pneumonia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a severe pneumonia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a severe pneumonia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.