Clinical trials
Shift Work Sleep Disorder clinical trials
Below are recruiting shift work sleep disorder clinical trials, each written for real people, not researchers. We’re tracking 36 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05424406Recruiting
Studying sleep timing changes in people with night-shift disorder
This study looks at how changes in your body clock (circadian timing) relate to “shift work disorder” in people who work night shifts. It may help researchers understand what drives symptoms and how to better target treatment.
Novi, MichiganAges 18 years+ - NCT06568367RecruitingPhase 3
Solriamfetol for shift work disorder (SUSTAIN trial)
This study tests a medication called Solriamfetol (Sunosi) to see if it helps people with shift work disorder stay awake and alert during their shifts. It is a Phase 3 trial, which means it is being studied in a larger group to confirm how well it works and check for side effects.
Auburn, AlabamaAges 18–65 - NCT07702344Recruiting
Shift work and your body's daily rhythm
This study looks at how shift work affects your body's natural daily rhythm (circadian rhythm) and overall health. It may help find ways to support the health of shift workers like you.
IstanbulAges 18–65 - NCT04966351Recruiting
Study countermeasures for disrupted body clock timing
This study tests ways to help your body’s internal clock stay in sync when your sleep timing is off. It’s looking for healthy adults with fairly regular sleep and certain lifestyle and location history.
Fort Collins, ColoradoAges 18–35 - NCT06384742Recruiting
Sleep help for nurses working night shifts
This study tests a program to help nurses and nursing staff who work night shifts improve their sleep. It's a 6-month online program that may help you sleep better and feel more rested.
Corvallis, OregonAges 18–65 - NCT06422741Recruiting
Grape seed extract for cholesterol in night shift workers
This study tests whether a grape seed extract supplement can help lower LDL (bad) cholesterol in people who work rotating night shifts. It is looking for healthy adults with moderately high cholesterol who are not taking cholesterol medicine.
Reus, TarragonaAges 18 years+ - NCT06492109Recruiting
Blood study on sleep loss
This study looks at blood samples to understand how sleep loss affects the body. It may help find new ways to diagnose or treat sleep problems.
Hangzhou, ZhejiangAges 18–80 - NCT06550115Recruiting
Night shift workers and their blood vessel & sugar health
This trial studies how sleep patterns affect blood vessel health and sugar control in long-term night shift workers. It may help find better ways to prevent heart problems and diabetes.
Fort Collins, ColoradoAges 18–65 - NCT06809335Recruiting
Better sleep app study for night shift workers
This study tests a phone app called SHIFT that gives you personalized light recommendations to help you sleep better during the day after night shifts. If you work nights and struggle to get enough daytime sleep, this could help you feel more rested.
Novi, MichiganAges 18 years+ - NCT07085819Recruiting
Can a plant extract help improve non-restorative sleep?
This study tests a natural plant extract given as a daily supplement to see if it helps people who feel their sleep is not refreshing, even when they get enough sleep. If you often wake up tired and are looking for a non-medication option, this trial may be a good fit.
CorkAges 18–65 - NCT07438912Recruiting
Mind After Midnight: A study on late-night thinking and suicide risk
This study looks at how thinking changes late at night in people who have had suicidal thoughts in the past 6 months. The goal is to understand risk and find better ways to help.
Tucson, ArizonaAges 18–55 - NCT06226025RecruitingPhase 2
Melatonin for Bipolar Disorder in Night Owls
This trial tests whether giving melatonin at the right time can help people with bipolar disorder who are night owls improve their mood and sleep. You would take melatonin or a placebo each evening for a few weeks while tracking your symptoms on a phone app.
Ann Arbor, MichiganAges 18–60 - NCT06949644Recruiting
Pupil light reflex test in delayed sleep phase disorder
This study uses a simple camera test (pupillometry) to measure how your pupils react to light, which may help understand delayed sleep-wake phase disorder. It could be a way to better diagnose or treat this condition.
Chicago, IllinoisAges 16 years+ - NCT07573488Recruiting
Sleep, Stress, and Migraine: Observation and Training Study
This study explores how sleep and stress affect migraine headaches and tests whether improving sleep habits can help reduce migraines. You'll be observed and taught strategies over several months while researchers track your headaches and sleep patterns.
ZurichAges 18–65 - NCT06669507Recruiting
Sleep clinic study on non-drug treatment options
This study looks at how people with certain sleep disorders respond to non-medication treatments. If you have trouble with your sleep-wake cycle and would like behavioral or lifestyle help instead of drugs, this trial might be for you.
TrondheimAges 18 years+ - NCT05908591Recruiting
Pregnancy sleep study on breathing, blood vessel function, and safety
This study looks at how sleep and breathing changes during pregnancy may affect blood vessel function and pregnancy safety. You may be asked about your sleep and possibly have health checks during the middle of pregnancy.
Edmonton, AlbertaAges 18 years+ - NCT06104280Recruiting
How opioid addiction meds affect sleep and eyes
This study tests how three common medications for opioid use disorder (methadone, buprenorphine, and naltrexone) affect eye function, sleep, and daily body rhythms. It may help find ways to improve treatment for opioid addiction.
Birmingham, AlabamaAges 18–80 - NCT06129942Recruiting
Light therapy for Parkinson's disease
This trial tests whether regular light therapy can help people with Parkinson's disease. It is designed for patients whose symptoms are at a moderate stage and whose medication has been stable for a month or more.
Suzhou, JiangsuAges 50–80 - NCT05986604Recruiting
Improving Sleep and Daily Rhythms for Older Adults
This study tests a treatment that helps improve sleep and daily rhythms, which may also help with memory and moving around. It's for people aged 50+, with low income, who have trouble with mobility and sleep.
Berkeley, CaliforniaAges 50 years+ - NCT06832007Recruiting
Light therapy for recovery from opioid use disorder
This study tests whether a special light device used at home can improve recovery in people being treated for opioid use disorder. It looks at how light might help with sleep, mood, and overall well-being.
Birmingham, AlabamaAges 18–60 - NCT06496282RecruitingPhase 3
Lemborexant for better sleep in shift workers
This study tests a sleep medication called lemborexant to see if it helps people who work rotating shifts sleep better and feel less sleepy during their shifts.
Ratchathewi, BangkokAges 20–60 - NCT07542756RecruitingPhase 4
Testing Common Sleep Medications for Insomnia
This study compares how well different over-the-counter and prescription sleep medications work for insomnia. Researchers will guide you through trying medications one at a time to find what works best for your sleep problems.
Philadelphia, PennsylvaniaAges 18–80 - NCT06670287Recruiting
Tracking sleep in night shift workers
This study uses sensors to track your sleep patterns. If you work fixed night shifts, researchers want to learn how to better measure your sleep.
Novi, MichiganAges 18 years+ - NCT05530863Enrolling by invitation
Relaxation methods for insomnia during pregnancy
This study tests relaxation-based approaches to help pregnant people who have trouble falling asleep or waking up during the night. If you meet the sleep and pregnancy timing needs, the goal is to see whether the approach can improve sleep.
Philadelphia, PennsylvaniaAges 18–55
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Common questions
- Are there clinical trials for shift work sleep disorder?
- Yes. Clin2 currently lists 36 recruiting shift work sleep disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a shift work sleep disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a shift work sleep disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.