Clinical trials
Skin clinical trials
Below are recruiting skin clinical trials, each written for real people, not researchers. We’re tracking 645 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT00177268Recruiting
Collecting blood and tissue samples in skin diseases research
This study collects blood, urine, and possibly small tissue samples to learn more about cutaneous T-cell lymphoma (CTCL) and either eczema or atopic dermatitis. It may help researchers better understand these skin conditions and improve future treatments.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05047094Recruiting
DaRT radiation plus pembrolizumab for head and neck cancer
This trial tests whether a targeted internal radiation treatment (DaRT) combined with pembrolizumab (an immune therapy) can shrink recurrent or metastatic head and neck squamous cell cancer that cannot be fully removed with surgery. It may help by making cancer more visible to the immune system while delivering localized radiation to a tumor area.
JerusalemAges 18 years+ - NCT05036707RecruitingPhase 1/Phase 2
Tick bite study in healthy adults
This study looks at how your body's immune system reacts to a tick bite. It may help doctors understand and prevent tick-borne diseases, which are illnesses spread by ticks, like Lyme disease.
Bethesda, MarylandAges 18–99 - NCT04875078Enrolling by invitation
UVA-1 light treatment for hand skin tightness in scleroderma
This study tests whether UVA-1 light sessions can loosen tight skin and improve hand function in people with scleroderma. If you qualify, you would attend UVA-1 treatments twice a week for the study period.
Murray, UtahAges 18 years+ - NCT04875715RecruitingPhase 4
Almond oil cream vs hydroquinone for facial dark spots
This trial compares topical almond oil to hydroquinone to see which works better to reduce facial pigmentation (darkness). You may join if you fit certain skin-type and health needs and can follow a schedule of stopping or changing other face products during the study.
Sacramento, CaliforniaAges 18 years+ - NCT04650256Recruiting
Chinese herbal add-on after breast surgery
This trial looks at whether a Chinese herbal complementary treatment used alongside standard radiation after breast cancer surgery can improve health outcomes. It is for women newly diagnosed with certain stages of breast cancer who are planning chest-wall radiation.
Miami, FloridaAges 18 years+ - NCT04534127Recruiting
DaRT radiation device for skin and mouth or superficial tumors
This trial tests a targeted radiation device (DaRT seeds) to treat certain cancers on the skin, in the mouth, or in superficial soft tissue. It may help when standard treatment (like surgery or regular radiation/chemo) hasn’t worked, isn’t safe, or isn’t wanted.
JerusalemAges 18 years+ - NCT04475640Recruiting
Genetic testing study for cancer patients in different ethnic groups
This study looks at cancer-related inherited gene changes using blood samples. It may help patients and doctors understand cancer risk and guide treatment planning, especially across different ethnic communities.
Scottsdale, ArizonaAges 18 years+ - NCT04305691RecruitingPhase 2
Ixazomib for skin Kaposi sarcoma in people with HIV
This trial studies ixazomib (a targeted anti-cancer medicine) to treat cutaneous (skin) Kaposi sarcoma. It aims to shrink measurable skin lesions and improve symptoms, especially in people living with HIV.
San Diego, CaliforniaAges 18 years+ - NCT04272515Recruiting
Learn from tissue or samples from biliary atresia patients
This study looks to better understand biliary atresia by studying patient information and/or samples. It may help researchers learn why the condition happens and how to improve care.
Paris, DeAges Any age - NCT04256018RecruitingPhase 2
Mogamulizumab with low-dose skin radiation for lymphoma skin disease
This Phase 2 study tests mogamulizumab together with low-dose total skin electron beam radiation to treat mycosis fungoides or Sézary syndrome, two types of skin lymphoma. It may help shrink skin disease and control symptoms by combining an immune-targeting medicine with skin-focused radiation.
Stanford, CaliforniaAges 18 years+ - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Phoenix, ArizonaAges birth–20 years - NCT04344119Recruiting
Study of chilblains during COVID-19 infection
This study looks at skin lesions (chilblains) that appear in people with a confirmed COVID-19 infection. It aims to better understand these skin changes.
NiceAges Up to 90 years - NCT04354064Recruiting
Blood DNA test to see early treatment response in solid tumors
This study looks at circulating tumor DNA, which is tiny bits of DNA found in blood, to help assess how solid tumors are responding early. It uses blood samples from healthy adults who are willing to donate.
St Louis, MissouriAges 18 years+ - NCT04273061RecruitingPhase 2
Atezolizumab for tumors that look sensitive on DNA/RNA testing
This Phase 2 study tests atezolizumab, an immunotherapy drug, in people with advanced, incurable solid tumors whose tumor DNA/RNA suggests they may respond. The goal is to see if the treatment works better for patients selected by these lab results.
Vancouver, British ColumbiaAges 18 years+ - NCT04170244Recruiting
Skin microbiome study in atopic dermatitis and psoriasis
This study looks at the skin’s germs (“microbiome”) in people with atopic dermatitis (eczema) or psoriasis. It may help researchers better understand what’s going on on the skin and how that might relate to disease severity.
Rochester, New YorkAges 13 years+ - NCT04068155Recruiting
Radiation device for certain skin cancers you can treat locally
This trial tests a radiation-emitting device placed near the tumor to treat certain malignant skin cancers that can be fully covered. It may help shrink or control the cancer at the skin site where the device is applied.
GrenobleAges 18 years+ - NCT03952637RecruitingPhase 1/Phase 2
Gene therapy for GM1 disease with IV delivery
This early-stage study tests an IV gene therapy that delivers a working copy of an enzyme gene to help the body make beta-galactosidase in GM1 gangliosidosis. It may help slow or improve disease symptoms and looks closely at safety and how well the treatment works.
Bethesda, MarylandAges 6 months–12 years - NCT03612310Recruiting
Study uses stem cells to model genetic diseases
This study looks at how to create laboratory models of genetic diseases using stem cells made from people’s cells. It may help researchers understand disease causes and how treatments could work, using genetic patients (and some non-patient controls).
Edinburgh, MidlothianAges 1–120 - NCT03561376RecruitingEarly Phase 1
Zinc ointment versus petroleum jelly after skin surgery
This early-phase trial compares zinc oxide ointment versus petroleum jelly to help healing and scar appearance after certain skin surgeries. You might be able to join if you are having a suitable, uninfected, non-scalp skin incision and can use the study ointment.
Pittsburgh, PA, PennsylvaniaAges 18 years+ - NCT03577327Recruiting
Study gut and skin germs in vitiligo progression
This study looks at differences in the gut and skin microbiome (the germs living in and on the body) in people with vitiligo and in people without vitiligo. It aims to understand what might be linked to how vitiligo spreads over time.
Chicago, IllinoisAges 18–89 - NCT03564483Recruiting
Study for vulvar or anal skin cancer called EMPD
This study is for women with a specific rare skin cancer called extramammary Paget’s disease (EMPD) in the vulvar or perianal area. The goal is to better understand the condition and test an approach for people with primary or returning (recurrent) disease in those locations.
Rochester, MinnesotaAges 18 years+ - NCT03510442Recruiting
Study of genetics and causes of systemic juvenile arthritis and Still's disease
This study aims to learn more about the causes and genetics of two related inflammatory conditions: systemic juvenile idiopathic arthritis (sJIA) in children and adult-onset Still's disease (AOSD) in adults. By studying patients and healthy volunteers, researchers hope to understand these diseases better and find better ways to treat them.
Bethesda, MarylandAges 1 day–100 years - NCT03417856Enrolling by invitation
Study skin and blood signs in ichthyosis
This study looks at “skin and blood biomarkers,” meaning measurable signs in the body, in people with ichthyosis to better understand the condition. It may help researchers find ways to track disease activity and evaluate future treatments.
Chicago, IllinoisAges 1–60
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Common questions
- Are there clinical trials for skin?
- Yes. Clin2 currently lists 645 recruiting skin studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a skin trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a skin trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.