Clinical trials · South Carolina
Stroke clinical trials in South Carolina
We’re tracking 36 recruiting stroke studies with a site in South Carolina — including Early Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in South Carolina
- NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Greenville, South CarolinaAges 18–90 - NCT05338697Recruiting
Early testing after stroke to predict recovery outcomes
This study checks early brain and arm/hand signals soon after a stroke to better predict how well people recover by about 90 days. It may help future, better-targeted stroke recovery studies by improving how recovery chances are measured early.
Charleston, South CarolinaAges 18 years+ - NCT07039305Recruiting
Building physical strength after stroke
This study looks at whether a specific exercise program can help people with chronic stroke (more than 6 months ago) who still have some weakness in their leg. It aims to improve walking and overall physical ability.
Charleston, South CarolinaAges 18–80 - NCT07113067RecruitingPhase 1/Phase 2
Accelerated rTMS for Stroke Apathy
This study tests a non-invasive brain stimulation treatment called rTMS to see if it can help reduce apathy (lack of motivation) after a stroke. You would receive either real rTMS or a sham (fake) treatment over several sessions.
Charleston, South CarolinaAges 40 years+ - NCT07491952Recruiting
Continuous Dual Aspiration for Stroke With Zoom System
This trial tests a new way to remove blood clots from the brain using the Zoom System with a continuous double-suction technique (CDAT). It aims to see how well this approach works for people having a stroke caused by a large vessel blockage.
Greenville, South CarolinaAges 18 years+ - NCT06692686Recruiting
Testing ankle braces to improve walking after stroke
This trial is studying how different types of ankle braces (AFOs) affect walking ability in people who have had a stroke. It may help find the best brace to improve mobility.
Charleston, South CarolinaAges 18 years+ - NCT05901675Recruiting
Weight loss and exercise after stroke in walking recovery
This trial studies whether a weight-loss plan combined with exercise can improve walking and leg movement after stroke. It may help if you have ongoing leg weakness but can still walk without devices for testing.
Charleston, South CarolinaAges 35–85 - NCT07050355Recruiting
Brain stimulation and exercise for depression after stroke
This study tests whether combining brain stimulation with aerobic exercise can help treat depression and improve walking in people who have had a stroke at least a year ago. If you have ongoing depressive symptoms and some leg weakness from your stroke, this treatment may help you feel better and walk more easily.
Charleston, South CarolinaAges 21 years+ - NCT05701280Recruiting
Deep brain stimulation plus rehab after stroke
This trial looks at whether adding deep brain stimulation (a surgically placed device that delivers therapy signals) to rehab can improve arm function after a stroke. It is aimed at people whose stroke happened 12 months to 6 years ago and who still have arm weakness or poor control.
Charleston, South CarolinaAges 21 years+ - NCT03821129Recruiting
Reduce recurrent stroke with a PFO closure device and antiplatelet pills
This study looks at whether closing a heart opening called a patent foramen ovale (PFO) with a special septal occluder, along with antiplatelet medications, can lower the risk of another stroke. It is for people who recently had a stroke thought to be caused by a clot that traveled from the heart but without another clear source.
Charleston, South CarolinaAges 18–70 - NCT04682223Recruiting
Online speech therapy for people with stroke-related aphasia
This study tests whether telerehabilitation (therapy done by video/remote technology) can improve communication after a stroke caused aphasia. It may help you practice speech and understanding skills at home or from a convenient location.
Columbia, South CarolinaAges 21–80 - NCT04877444RecruitingEarly Phase 1
Exercise program to improve arm recovery after stroke
This early-stage trial tests a special exercise approach meant to “prime” the brain and improve arm movement after a stroke. You may be eligible if you’re 6+ months out from a one-sided stroke and can safely do an exercise test.
Charleston, South CarolinaAges 50–90 - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Charleston, South CarolinaAges 1–120 - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Charleston, South CarolinaAges 18–79 - NCT05628324Recruiting
Game-based training using muscle signals after stroke
This trial tests whether an EMG-controlled computer game can help retrain how your arm muscles activate after stroke. It may help improve upper-limb movement by practicing with real-time muscle feedback.
Charleston, South CarolinaAges 18 years+ - NCT05760885RecruitingEarly Phase 1
Multisensory training to improve standing balance after stroke
This early-stage study tests a multisensory therapy to help people with ongoing balance problems stand more safely after a stroke. It may help your balance by giving targeted feedback to the foot and ankle while you practice standing.
Charleston, South CarolinaAges 21 years+ - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
Charleston, South CarolinaAges 18 years+ - NCT06052969Recruiting
Pulse NanoMED MicroBeads after clot removal for stroke
This trial tests a new treatment called Pulse NanoMED MicroBeads for people who still have a blocked brain artery after a standard clot removal procedure (mechanical thrombectomy). The goal is to see if these tiny beads can clear the remaining blockage and improve blood flow to the brain.
Columbia, South CarolinaAges 18–85 - NCT06322030Recruiting
Weight loss and exercise for stroke survivors
This study tests whether a weight loss and exercise program can help veterans who had a stroke at least 6 months ago and have some leg weakness. It aims to improve mobility and overall health.
Charleston, South CarolinaAges 40–80 - NCT06682429Recruiting
Home rehab program after stroke
This study tests a home-based therapy program delivered by video calls to help people recovering from a stroke improve arm function. It is designed for those with moderate arm weakness about 4 months after their stroke.
Charleston, South CarolinaAges 18–80 - NCT06782321Recruiting
Virtual emotional support after stroke
This study tests a virtual program to help with emotional recovery like anxiety or sadness after a stroke. You can join from home using your own device.
Charleston, South CarolinaAges 21 years+ - NCT07144436Recruiting
Pain after stroke: brain scan and treatment study
This trial tests whether a special kind of brain scan (called tAN-fMRI) can help understand and treat pain that happens after a stroke. You may qualify if you had a stroke at least 6 months ago and are between 18 and 80 years old.
Charleston, South CarolinaAges 18–80 - NCT07172464Recruiting
Study of a new device to close a hole in the heart after a stroke
This trial tests a new device to close a PFO (a small hole between the upper chambers of the heart) in people who have had a stroke caused by a blood clot. The goal is to prevent future strokes by blocking the hole.
Greenville, South CarolinaAges 18–65 - NCT07608588Recruiting
Brain Stimulation for Language Recovery After Stroke
This study tests whether a non-invasive brain stimulation technique called rTMS can help people regain language skills after a left-sided stroke, particularly for word-finding and meaning difficulties. Researchers will target specific brain regions to see if stimulation improves recovery.
Columbia, South CarolinaAges 18 years+
Stroke trials by city in South Carolina
Where these studies are running in South Carolina
Institutions with a site for the recruiting stroke studies listed above.
- Medical University of South Carolina · 12 studies
- Prisma Health Cancer Institute · 4 studies
- Ralph H. Johnson VA Medical Center · 4 studies
- University of South Carolina · 2 studies
- 30 Bee Street
- College of Health Professions
- McCausland Center
- Medical University of South Carolia
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Stroke trials in other states
Common questions
- Are there stroke clinical trials in South Carolina?
- Yes. We're currently tracking 36 recruiting stroke studies with a site in South Carolina, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study in South Carolina?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in South Carolina to take part?
- Not necessarily. These studies have a site in South Carolina, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open in South Carolina regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.