Clinical trials · Charleston, SC
Stroke clinical trials in Charleston
We’re tracking 25 recruiting stroke studies with a site in or near Charleston — including Early Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Charleston
- NCT07039305Recruiting
Building physical strength after stroke
This study looks at whether a specific exercise program can help people with chronic stroke (more than 6 months ago) who still have some weakness in their leg. It aims to improve walking and overall physical ability.
Charleston, South CarolinaAges 18–80 - NCT05338697Recruiting
Early testing after stroke to predict recovery outcomes
This study checks early brain and arm/hand signals soon after a stroke to better predict how well people recover by about 90 days. It may help future, better-targeted stroke recovery studies by improving how recovery chances are measured early.
Charleston, South CarolinaAges 18 years+ - NCT07356011Recruiting
Exoskeleton for balance after stroke
This trial tests whether wearing a robotic exoskeleton can help improve balance and reduce falls in people who had a stroke at least 6 months ago and still have leg weakness. It may be a good fit if you are worried about falling and can walk on a treadmill without a cane or walker.
Charleston, South CarolinaAges 21 years+ - NCT06682429Recruiting
Home rehab program after stroke
This study tests a home-based therapy program delivered by video calls to help people recovering from a stroke improve arm function. It is designed for those with moderate arm weakness about 4 months after their stroke.
Charleston, South CarolinaAges 18–80 - NCT07050355Recruiting
Brain stimulation and exercise for depression after stroke
This study tests whether combining brain stimulation with aerobic exercise can help treat depression and improve walking in people who have had a stroke at least a year ago. If you have ongoing depressive symptoms and some leg weakness from your stroke, this treatment may help you feel better and walk more easily.
Charleston, South CarolinaAges 21 years+ - NCT06782321Recruiting
Virtual emotional support after stroke
This study tests a virtual program to help with emotional recovery like anxiety or sadness after a stroke. You can join from home using your own device.
Charleston, South CarolinaAges 21 years+ - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
Charleston, South CarolinaAges 18 years+ - NCT07113067RecruitingPhase 1/Phase 2
Accelerated rTMS for Stroke Apathy
This study tests a non-invasive brain stimulation treatment called rTMS to see if it can help reduce apathy (lack of motivation) after a stroke. You would receive either real rTMS or a sham (fake) treatment over several sessions.
Charleston, South CarolinaAges 40 years+ - NCT05760885RecruitingEarly Phase 1
Multisensory training to improve standing balance after stroke
This early-stage study tests a multisensory therapy to help people with ongoing balance problems stand more safely after a stroke. It may help your balance by giving targeted feedback to the foot and ankle while you practice standing.
Charleston, South CarolinaAges 21 years+ - NCT03907046RecruitingPhase 3
Blood thinner study to prevent stroke after brain bleed
This Phase 3 study tests whether a blood thinner (apixaban) can help prevent another stroke and support recovery after you’ve had a brain bleed. You would be assigned to a treatment group, and the study checks safety and whether strokes can be reduced without causing dangerous bleeding.
Charleston, South CarolinaAges 18 years+ - NCT03843463RecruitingPhase 2
Escitalopram plus language therapy after left stroke
This trial tests whether the antidepressant medicine escitalopram, along with language therapy, can improve language skills after a recent stroke that affected the left side of the brain. It may help some people with stroke-related aphasia (language difficulty) regain words and communication.
Charleston, South CarolinaAges 18–99 - NCT07227246RecruitingPhase 3
Testing rFVIIa for bleeding stroke within 2 hours
This trial tests whether a drug called Recombinant Factor VIIa (rFVIIa) can safely help stop bleeding in the brain during a hemorrhagic stroke. The goal is to give the drug as quickly as possible, within 2 hours of stroke onset, to see if it improves outcomes.
Charleston, South CarolinaAges 18–80 - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Charleston, South CarolinaAges 1–120 - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Charleston, South CarolinaAges 18–79 - NCT05901675Recruiting
Weight loss and exercise after stroke in walking recovery
This trial studies whether a weight-loss plan combined with exercise can improve walking and leg movement after stroke. It may help if you have ongoing leg weakness but can still walk without devices for testing.
Charleston, South CarolinaAges 35–85 - NCT06289985Recruiting
Expanding clot removal for medium vessel strokes
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
Charleston, South CarolinaAges 18 years+ - NCT04877444RecruitingEarly Phase 1
Exercise program to improve arm recovery after stroke
This early-stage trial tests a special exercise approach meant to “prime” the brain and improve arm movement after a stroke. You may be eligible if you’re 6+ months out from a one-sided stroke and can safely do an exercise test.
Charleston, South CarolinaAges 50–90 - NCT06692686Recruiting
Testing ankle braces to improve walking after stroke
This trial is studying how different types of ankle braces (AFOs) affect walking ability in people who have had a stroke. It may help find the best brace to improve mobility.
Charleston, South CarolinaAges 18 years+ - NCT07144436Recruiting
Pain after stroke: brain scan and treatment study
This trial tests whether a special kind of brain scan (called tAN-fMRI) can help understand and treat pain that happens after a stroke. You may qualify if you had a stroke at least 6 months ago and are between 18 and 80 years old.
Charleston, South CarolinaAges 18–80 - NCT03821129Recruiting
Reduce recurrent stroke with a PFO closure device and antiplatelet pills
This study looks at whether closing a heart opening called a patent foramen ovale (PFO) with a special septal occluder, along with antiplatelet medications, can lower the risk of another stroke. It is for people who recently had a stroke thought to be caused by a clot that traveled from the heart but without another clear source.
Charleston, South CarolinaAges 18–70 - NCT05628324Recruiting
Game-based training using muscle signals after stroke
This trial tests whether an EMG-controlled computer game can help retrain how your arm muscles activate after stroke. It may help improve upper-limb movement by practicing with real-time muscle feedback.
Charleston, South CarolinaAges 18 years+ - NCT05537753Recruiting
PFO closure device test after recent unexplained stroke
This trial tests whether closing a hole in the heart (a PFO) with a special device can help prevent another stroke after an unexplained stroke. You may be a candidate if your stroke likely happened because blood can pass through this PFO.
Charleston, South CarolinaAges 18–60 - NCT05701280Recruiting
Deep brain stimulation plus rehab after stroke
This trial looks at whether adding deep brain stimulation (a surgically placed device that delivers therapy signals) to rehab can improve arm function after a stroke. It is aimed at people whose stroke happened 12 months to 6 years ago and who still have arm weakness or poor control.
Charleston, South CarolinaAges 21 years+ - NCT06039176Recruiting
Learning from the HeartMate 3 device
This study looks at information from the HeartMate 3 LVAD device to learn more about how it works and what it can tell us about the future. It may help people with advanced heart failure who need this specific device.
Charleston, South CarolinaAges 18–100
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Stroke trials in other cities
Where these studies are running near Charleston
Institutions with a site for the recruiting stroke studies listed above.
- Medical University of South Carolina · 19 studies
- Ralph H. Johnson VA Medical Center · 3 studies
- 30 Bee Street
- College of Health Professions
- Medical University of South Carolia
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting stroke studies in South Carolina.
Common questions
- Are there stroke clinical trials near Charleston?
- Yes. We're currently tracking 25 recruiting stroke studies with a site near Charleston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study near Charleston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Charleston to take part?
- Not necessarily. These studies have a site near Charleston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open near Charleston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.