Clinical trials · Massachusetts
Stroke clinical trials in Massachusetts
We’re tracking 46 recruiting stroke studies with a site in Massachusetts — including Early Phase 1, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT05911568Recruiting
Clot-removal treatment for stroke patients with existing disability
This trial studies whether an endovascular (catheter-based) procedure to treat a certain type of blocked artery can improve outcomes for people who already had trouble functioning before their stroke. You may be considered if your stroke is confirmed early and your scans show the right type and location of blockage.
Boston, MassachusettsAges 18 years+ - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Worcester, MassachusettsAges 18–90 - NCT05338697Recruiting
Early testing after stroke to predict recovery outcomes
This study checks early brain and arm/hand signals soon after a stroke to better predict how well people recover by about 90 days. It may help future, better-targeted stroke recovery studies by improving how recovery chances are measured early.
Boston, MassachusettsAges 18 years+ - NCT05626894RecruitingPhase 2
Wrist sensor app to help use the weaker arm at home
This Phase 2 study tests a new wrist sensor system that tracks arm movement and gives feedback using a phone or tablet. It aims to improve daily use of the weaker (hemiparetic) arm in people with a prior stroke.
Boston, MassachusettsAges 18–85 - NCT06797154Recruiting
Stroke recovery study: wrist sensor to boost arm use
This study tests a wrist-worn sensor that vibrates to remind you to use your weaker arm. It's designed for people who had a stroke 1 to 6 months ago and have some arm weakness, to help them use their affected arm more during daily activities.
Boston, MassachusettsAges 18–85 - NCT06998485Recruiting
Arm recovery after a first stroke
This study tests an intensive 6-week arm training program for people who had a first stroke 3 to 6 months ago and still have arm weakness. The goal is to see how the brain can recover arm function.
Boston, MassachusettsAges 18 years+ - NCT07414732Recruiting
Testing a new approach to help stroke survivors take blood pressure pills
This trial tests a simple program to help people who have had a stroke stick with their blood pressure medication. It uses text messages and a medication organizer to make it easier to remember pills and keep blood pressure under control.
Boston, MassachusettsAges 18–99 - NCT05723926Recruiting
Carotid implants to help prevent stroke repeat in atrial fibrillation
This trial tests whether placing a carotid implant can reduce the chance of having another stroke in people with atrial fibrillation who are already taking blood thinners. It aims to prevent stroke recurrence while you continue prescribed anticoagulation.
Boston, MassachusettsAges 18 years+ - NCT07392450RecruitingPhase 2
Study of TAK-755 for adults with acute ischemic stroke
This trial tests if TAK-755 can help people who have had a moderate to severe stroke within the last 24 hours. It aims to see if the drug can improve recovery by protecting brain tissue that is still salvageable.
Boston, MassachusettsAges 18 years+ - NCT07218094Enrolling by invitation
Exosuit walking study for chronic stroke survivors
This study tests a robotic leg suit (exosuit) to help improve walking after a stroke. You may be eligible if you had a stroke more than 6 months ago and still have trouble walking safely.
Boston, MassachusettsAges 18 years+ - NCT05983185Recruiting
Prism adaptation therapy for right brain stroke recovery
This study tests whether prism adaptation therapy (wearing special glasses that shift how you see) can help improve attention and function after a right-brain stroke. You may be eligible if you recently had a first right-brain stroke and can sit up to take part in the therapy.
Leeds, MassachusettsAges 18 years+ - NCT07739875Recruiting
App-based therapy for post-stroke word-finding
This trial tests a therapy delivered through a smartphone app to help people with aphasia (trouble finding words after a stroke) improve their ability to name things. The therapy happens in daily life, not in a clinic, and is personalized to the words you need most.
Boston, MassachusettsAges 18–89 - NCT05701280Recruiting
Deep brain stimulation plus rehab after stroke
This trial looks at whether adding deep brain stimulation (a surgically placed device that delivers therapy signals) to rehab can improve arm function after a stroke. It is aimed at people whose stroke happened 12 months to 6 years ago and who still have arm weakness or poor control.
Boston, MassachusettsAges 21 years+ - NCT03485040Recruiting
Rehab study for arm weakness after stroke
This study tests a rehabilitation approach to help people recover arm movement after an ischemic or bleeding stroke. You may be able to join if you’re currently an inpatient in the stroke neurology unit and have arm weakness but are medically stable and able to follow simple instructions.
Boston, MassachusettsAges 18–90 - NCT03821129Recruiting
Reduce recurrent stroke with a PFO closure device and antiplatelet pills
This study looks at whether closing a heart opening called a patent foramen ovale (PFO) with a special septal occluder, along with antiplatelet medications, can lower the risk of another stroke. It is for people who recently had a stroke thought to be caused by a clot that traveled from the heart but without another clear source.
Boston, MassachusettsAges 18–70 - NCT07588932RecruitingEarly Phase 1
Medication and Robot Training for Stroke Arm Recovery
This study tests whether three medications (Telmisartan, Cilostazol, and Metformin) combined with robotic arm training can help people improve arm movement and strength after a chronic stroke. You would participate in supervised training sessions using a robotic rehabilitation system.
Charlestown, MassachusettsAges 21–80 - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Boston, MassachusettsAges 18 years+ - NCT06787729Recruiting
Using sensors and a smartphone to help arm recovery after stroke
This study tests if wearing small sensors on your arm at home and using a smartphone app can help improve how you use your weaker arm after a stroke. It is designed for people who are at least a year past their stroke and want to take an active role in their recovery.
Charlestown, MassachusettsAges 18–80 - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Boston, MassachusettsAges 1–120 - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Worcester, MassachusettsAges 18–79 - NCT05756257Recruiting
MRI study of blood pressure swings after ischemic stroke
This trial looks at whether changes in blood pressure after an ischemic stroke (a stroke caused by blocked blood flow) are linked to recovery and outcomes. You may be asked to have MRI scans soon after arriving to help researchers understand who is at higher risk and why.
Boston, MassachusettsAges 18 years+ - NCT05832567Recruiting
Study of hidden and open placebo effects in stroke recovery
This study looks at how “open” (told) and “hidden” (not told) placebo effects may change arm recovery after a long-term stroke. You would do recovery-related assessments and likely receive brain-stimulation or related procedures to test these effects.
Cambridge, MassachusettsAges 18 years+ - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
Boston, MassachusettsAges 18 years+ - NCT06682429Recruiting
Home rehab program after stroke
This study tests a home-based therapy program delivered by video calls to help people recovering from a stroke improve arm function. It is designed for those with moderate arm weakness about 4 months after their stroke.
Boston, MassachusettsAges 18–80
Stroke trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting stroke studies listed above.
- Massachusetts General Hospital · 11 studies
- Spaulding Rehabilitation Hospital · 6 studies
- Boston Medical Center · 3 studies
- Baystate Medical Center · 2 studies
- University of Massachusetts Chan Medical School · 2 studies
- Beth Israel Deaconess Medical Center
- Boston University Medical Center
- Boston University Neuromotor Recovery Laboratory
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Stroke trials in other states
Common questions
- Are there stroke clinical trials in Massachusetts?
- Yes. We're currently tracking 46 recruiting stroke studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.