Clinical trials · Illinois
Stroke clinical trials in Illinois
We’re tracking 55 recruiting stroke studies with a site in Illinois — including Early Phase 1, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Illinois
- NCT05911568Recruiting
Clot-removal treatment for stroke patients with existing disability
This trial studies whether an endovascular (catheter-based) procedure to treat a certain type of blocked artery can improve outcomes for people who already had trouble functioning before their stroke. You may be considered if your stroke is confirmed early and your scans show the right type and location of blockage.
Chicago, IllinoisAges 18 years+ - NCT06094478Recruiting
Stroke emergency protocol study
This study tests a hospital stroke protocol to quickly evaluate and manage patients with a stroke caused by a clot (AIS), bleeding in the brain (ICH), or bleeding around the brain (SAH). It may help improve emergency care and outcomes.
Chicago, IllinoisAges 18 years+ - NCT05338697Recruiting
Early testing after stroke to predict recovery outcomes
This study checks early brain and arm/hand signals soon after a stroke to better predict how well people recover by about 90 days. It may help future, better-targeted stroke recovery studies by improving how recovery chances are measured early.
Park Ridge, IllinoisAges 18 years+ - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Peoria, IllinoisAges 18–90 - NCT06127602Recruiting
Electrical stimulation plus walking for stroke recovery
This study tests whether adding a type of electrical stimulation to leg muscles during walking can improve walking ability for people who are at least 6 months past a stroke. If you have weakness on one side and can walk on a treadmill with some help, you may be able to join.
Chicago, IllinoisAges 18–90 - NCT03401762Recruiting
Wearable device training for stroke arm coordination
This trial tests a wearable device and training task to help improve how stroke-affected arm muscles work together. It may help reduce unwanted “extra muscle effort” and improve control in people with recent or long-term stroke.
Chicago, IllinoisAges 21 years+ - NCT07806097Recruiting
Self-directed arm gaming during stroke rehab
This trial tests whether playing arm-focused video games on your own helps improve arm movement while you're in the hospital for stroke rehabilitation. You would play games that involve moving your arm and hand, and the goal is to see if this makes your recovery better.
Chicago, IllinoisAges 18 years+ - NCT07652970Recruiting
Home video therapy for severe stroke recovery
This study tests whether a new therapy done at home via video calls can help people with severe, long-lasting stroke regain leg movement and walking ability. If you have trouble walking or moving your leg on one side, this may be an option.
Chicago, IllinoisAges 18–80 - NCT06653855Recruiting
Cupping for leg stiffness and movement after stroke
This study tests if cupping therapy can reduce leg stiffness and improve movement in people recovering from a stroke. You must be getting rehab at a specific clinic in Joliet.
Joliet, IllinoisAges 30–80 - NCT06386874Recruiting
Magnetic field therapy for arm recovery after stroke
This study tests a new magnetic device applied to the head to help improve arm function after a stroke. You will use the device while doing exercises, and a caregiver will support you with a mobile app and video calls.
Chicago, IllinoisAges 22–80 - NCT06655636Recruiting
Testing a new robotic brace to help stroke survivors open their hand
This trial tests a wearable robotic device (ExoNET) that helps stroke survivors with hand weakness. It aims to see if the device is safe and helpful for people who had a stroke at least 8 months ago and still have trouble using their arm and hand.
Chicago, IllinoisAges 40–70 - NCT07430917RecruitingPhase 2
Testing J147 for recent stroke from blocked artery
This trial tests a new drug, J147, for people who recently had a stroke caused by a blocked artery and have already had a procedure to reopen that artery. It aims to see if the drug can improve recovery.
Rockford, IllinoisAges 18–90 - NCT07041775Recruiting
MINT video game training to improve walking after stroke
This study tests a new video-game–style training called MINT to help people who have had a stroke walk better. If you have trouble walking because one leg is weaker or slower than the other, this training might help improve your balance and coordination.
Chicago, IllinoisAges 18–85 - NCT03264261Recruiting
Therapy to improve walking after stroke by using affected arm
This study tests a walking-focused therapy called constraint induced movement therapy (CI therapy) to improve walking after a stroke. It may help people walk faster and more safely by encouraging more use of the more affected side.
Chicago, IllinoisAges 21–75 - NCT06950593Recruiting
Electrical stimulation for arm recovery after stroke
This trial tests if a mild electrical current applied to the skin can help improve arm function in people who had a stroke at least 6 months ago. It is for those with significant arm weakness who are not currently in regular therapy.
Chicago, IllinoisAges 18 years+ - NCT06666673RecruitingEarly Phase 1
Effects of a muscle relaxant on arm movement after stroke
This study looks at how the brain controls arm movements after a stroke. It tests whether a medication called tizanidine, which relaxes muscles, can improve arm function when combined with physical therapy.
Chicago, IllinoisAges 18–80 - NCT06638944RecruitingPhase 2
Wearable device training for swallowing after stroke or Parkinson's
This study tests a wearable device that gives feedback on swallowing exercises. It may improve swallowing safety after a stroke or for people with Parkinson's disease.
Champaign, IllinoisAges 50–90 - NCT06598150Recruiting
Brain mapping study for chronic arm weakness after stroke
This study uses MRI scans to understand how the brain controls arm movement in people who have had a stroke. It aims to help develop better rehabilitation therapies for chronic arm weakness.
Chicago, IllinoisAges 18 years+ - NCT06400186Recruiting
Walking training to improve balance after stroke
This trial tests a new walking training method designed to help you improve your balance after a stroke. It's for people who have had a stroke more than 6 months ago and can walk a short distance, with or without a cane or simple ankle brace.
Hines, IllinoisAges 18–80 - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
Chicago, IllinoisAges 18 years+ - NCT05849532Recruiting
Home electrical exercise for walking after stroke
This trial tests a home-based program using electrical stimulation to help people with long-term stroke improve walking and leg movement. If you qualify, you may use the device and a smartphone app at home with guidance from the study team.
Chicago, IllinoisAges 18–90 - NCT05756257Recruiting
MRI study of blood pressure swings after ischemic stroke
This trial looks at whether changes in blood pressure after an ischemic stroke (a stroke caused by blocked blood flow) are linked to recovery and outcomes. You may be asked to have MRI scans soon after arriving to help researchers understand who is at higher risk and why.
Chicago, IllinoisAges 18 years+ - NCT05723926Recruiting
Carotid implants to help prevent stroke repeat in atrial fibrillation
This trial tests whether placing a carotid implant can reduce the chance of having another stroke in people with atrial fibrillation who are already taking blood thinners. It aims to prevent stroke recurrence while you continue prescribed anticoagulation.
Rockford, IllinoisAges 18 years+ - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Chicago, IllinoisAges 18–79
Stroke trials by city in Illinois
Where these studies are running in Illinois
Institutions with a site for the recruiting stroke studies listed above.
- Northwestern University · 5 studies
- Shirley Ryan AbilityLab · 4 studies
- University of Chicago · 2 studies
- University of Chicago Medical Center · 2 studies
- University of Illinois at Chicago · 2 studies
- Abilitylab
- Advocate Lutheran General Hospital
- Ascension Alexian Brothers Health System
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Stroke trials in other states
Common questions
- Are there stroke clinical trials in Illinois?
- Yes. We're currently tracking 55 recruiting stroke studies with a site in Illinois, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study in Illinois?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Illinois to take part?
- Not necessarily. These studies have a site in Illinois, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open in Illinois regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.