Clinical trials · Illinois
Stroke clinical trials in Illinois
We’re tracking 55 recruiting stroke studies with a site in Illinois — including Early Phase 1, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Illinois
- NCT05911568Recruiting
Clot-removal treatment for stroke patients with existing disability
This trial studies whether an endovascular (catheter-based) procedure to treat a certain type of blocked artery can improve outcomes for people who already had trouble functioning before their stroke. You may be considered if your stroke is confirmed early and your scans show the right type and location of blockage.
Chicago, IllinoisAges 18 years+ - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Peoria, IllinoisAges 18–90 - NCT05338697Recruiting
Early testing after stroke to predict recovery outcomes
This study checks early brain and arm/hand signals soon after a stroke to better predict how well people recover by about 90 days. It may help future, better-targeted stroke recovery studies by improving how recovery chances are measured early.
Carbondale, IllinoisAges 18 years+ - NCT06094478Recruiting
Stroke emergency protocol study
This study tests a hospital stroke protocol to quickly evaluate and manage patients with a stroke caused by a clot (AIS), bleeding in the brain (ICH), or bleeding around the brain (SAH). It may help improve emergency care and outcomes.
Chicago, IllinoisAges 18 years+ - NCT03401762Recruiting
Wearable device training for stroke arm coordination
This trial tests a wearable device and training task to help improve how stroke-affected arm muscles work together. It may help reduce unwanted “extra muscle effort” and improve control in people with recent or long-term stroke.
Chicago, IllinoisAges 21 years+ - NCT06127602Recruiting
Electrical stimulation plus walking for stroke recovery
This study tests whether adding a type of electrical stimulation to leg muscles during walking can improve walking ability for people who are at least 6 months past a stroke. If you have weakness on one side and can walk on a treadmill with some help, you may be able to join.
Chicago, IllinoisAges 18–90 - NCT05723926Recruiting
Carotid implants to help prevent stroke repeat in atrial fibrillation
This trial tests whether placing a carotid implant can reduce the chance of having another stroke in people with atrial fibrillation who are already taking blood thinners. It aims to prevent stroke recurrence while you continue prescribed anticoagulation.
Rockford, IllinoisAges 18 years+ - NCT06666673RecruitingEarly Phase 1
Effects of a muscle relaxant on arm movement after stroke
This study looks at how the brain controls arm movements after a stroke. It tests whether a medication called tizanidine, which relaxes muscles, can improve arm function when combined with physical therapy.
Chicago, IllinoisAges 18–80 - NCT06400186Recruiting
Walking training to improve balance after stroke
This trial tests a new walking training method designed to help you improve your balance after a stroke. It's for people who have had a stroke more than 6 months ago and can walk a short distance, with or without a cane or simple ankle brace.
Chicago, IllinoisAges 18–80 - NCT04957355Recruiting
NMES therapy to improve balance and reduce falls after stroke
This trial tests whether NMES (a small electrical stimulation you feel on the skin) can improve balance and lower fall risk in people with stroke-related weakness. It may help you walk more steadily and safely, while the study measures balance and fall-related outcomes.
Chicago, IllinoisAges 18–90 - NCT05849532Recruiting
Home electrical exercise for walking after stroke
This trial tests a home-based program using electrical stimulation to help people with long-term stroke improve walking and leg movement. If you qualify, you may use the device and a smartphone app at home with guidance from the study team.
Chicago, IllinoisAges 18–90 - NCT06638944RecruitingPhase 2
Wearable device training for swallowing after stroke or Parkinson's
This study tests a wearable device that gives feedback on swallowing exercises. It may improve swallowing safety after a stroke or for people with Parkinson's disease.
Champaign, IllinoisAges 50–90 - NCT03264261Recruiting
Therapy to improve walking after stroke by using affected arm
This study tests a walking-focused therapy called constraint induced movement therapy (CI therapy) to improve walking after a stroke. It may help people walk faster and more safely by encouraging more use of the more affected side.
Chicago, IllinoisAges 21–75 - NCT03821129Recruiting
Reduce recurrent stroke with a PFO closure device and antiplatelet pills
This study looks at whether closing a heart opening called a patent foramen ovale (PFO) with a special septal occluder, along with antiplatelet medications, can lower the risk of another stroke. It is for people who recently had a stroke thought to be caused by a clot that traveled from the heart but without another clear source.
Chicago, IllinoisAges 18–70 - NCT04165616Recruiting
Early MRI and movement testing after a specific type of stroke
This study looks at how early brain imaging and careful arm/leg movement tests can help recovery after certain strokes. If you had a stroke affecting the motor pathway, this may help researchers better understand what predicts improvement.
Chicago, IllinoisAges 18–85 - NCT04219670Recruiting
Using sensors to study stroke recovery in hospital and community
This study uses sensor recordings to learn how stroke recovery happens over time, including for people in the hospital and those living in the community. Your results may help improve future monitoring and rehabilitation after stroke.
Chicago, IllinoisAges 18 years+ - NCT04312269Recruiting
Brain stimulation plus memory practice to improve stroke arm recovery
This trial tests whether a combined therapy—MyoCI plus memory “reactivation”—can improve arm movement recovery after stroke. It’s meant for people with ongoing arm weakness at least 6 months after their first stroke.
Chicago, IllinoisAges 21–100 - NCT04477330Recruiting
Brain stimulation to improve walking after a stroke
This study tests whether a brain stimulation method (“cortical priming”) can improve walking after a stroke. It may help people with ongoing walking problems improve gait and leg control over a rehabilitation program.
Chicago, IllinoisAges 18 years+ - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Chicago, IllinoisAges 18 years+ - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Chicago, IllinoisAges 1–120 - NCT05167786Recruiting
Electrical spinal cord stimulation for walking after stroke
This trial studies whether a non-surgical electrical treatment to the spinal area can improve walking and leg control after a stroke. It’s for people who have had a single stroke and still need hands-on support to walk.
Chicago, IllinoisAges 18 years+ - NCT05194566Recruiting
Brain stimulation for long-term speech trouble after stroke
This study tests whether a form of brain stimulation can improve naming words in people who still have language problems (aphasia) more than 6 months after a stroke. It may help people find and say words more accurately during a naming task.
Chicago, IllinoisAges 18–80 - NCT05479006Recruiting
tDCS for arm weakness after stroke
This trial tests whether a targeted, noninvasive brain stimulation (tDCS) can improve arm weakness and movement after stroke. It may help people who have significant trouble moving one arm on the side affected by stroke.
Urbana, IllinoisAges 18–90 - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Chicago, IllinoisAges 18–79
Stroke trials by city in Illinois
Where these studies are running in Illinois
Institutions with a site for the recruiting stroke studies listed above.
- Northwestern University · 5 studies
- Shirley Ryan AbilityLab · 5 studies
- University of Chicago · 4 studies
- University of Illinois · 4 studies
- Ascension Alexian Brothers · 2 studies
- Department of Physical Therapy and Human Movement Sciences · 2 studies
- Rush University Medical Center · 2 studies
- Advocate Lutheran General Hospital
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Stroke trials in other states
Common questions
- Are there stroke clinical trials in Illinois?
- Yes. We're currently tracking 55 recruiting stroke studies with a site in Illinois, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study in Illinois?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Illinois to take part?
- Not necessarily. These studies have a site in Illinois, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open in Illinois regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.