Clinical trials · Pennsylvania
Stroke clinical trials in Pennsylvania
We’re tracking 54 recruiting stroke studies with a site in Pennsylvania — including Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT07224178Recruiting
Heart strain and stroke of unknown cause
This study looks at how well the left side of the heart pumps (called strain) in people who had a stroke without a known cause. It aims to see if this heart measurement can help predict future strokes or heart rhythm problems like atrial fibrillation.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05911568Recruiting
Clot-removal treatment for stroke patients with existing disability
This trial studies whether an endovascular (catheter-based) procedure to treat a certain type of blocked artery can improve outcomes for people who already had trouble functioning before their stroke. You may be considered if your stroke is confirmed early and your scans show the right type and location of blockage.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05338697Recruiting
Early testing after stroke to predict recovery outcomes
This study checks early brain and arm/hand signals soon after a stroke to better predict how well people recover by about 90 days. It may help future, better-targeted stroke recovery studies by improving how recovery chances are measured early.
Hershey, PennsylvaniaAges 18 years+ - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Philadelphia, PennsylvaniaAges 18–90 - NCT07153536Recruiting
Spinal stimulation and therapy for arm weakness after stroke
This trial tests if electrical stimulation of the spinal cord, combined with physical therapy, can improve arm and hand function after a stroke. It is for people who have had a stroke more than 6 months ago and still have significant weakness in one arm.
Pittsburgh, PennsylvaniaAges 22–70 - NCT05691244RecruitingPhase 3
Tested drug for acute ischemic stroke within 24 hours
This Phase 3 trial studies sovateltide (and a placebo) in adults with an ischemic stroke, aiming to improve safety and outcomes. It focuses on people who can start treatment quickly after stroke symptoms begin and who do not have bleeding in the brain on imaging.
Hershey, PennsylvaniaAges 18–80 - NCT05140148RecruitingPhase 2
Amantadine to help recovery after stroke
This Phase 2 study tests whether the medicine amantadine can improve recovery after a recent stroke. It may help some people regain function during early rehabilitation.
Philadelphia, PennsylvaniaAges 18–85 - NCT07704840RecruitingPhase 2
Testing a new pill for post-stroke arm stiffness
This study tests an experimental pill (BMS-986368) that targets two brain chemicals to reduce muscle stiffness after a stroke. It's for people who had a stroke in the last 4 to 18 months and have moderate tightness in their elbow and wrist.
Elkins Park, PennsylvaniaAges 18–80 - NCT06386874Recruiting
Magnetic field therapy for arm recovery after stroke
This study tests a new magnetic device applied to the head to help improve arm function after a stroke. You will use the device while doing exercises, and a caregiver will support you with a mobile app and video calls.
Elkins Park, PennsylvaniaAges 22–80 - NCT03347786RecruitingPhase 1/Phase 2
Verapamil to protect the brain after acute stroke
This trial tests whether verapamil, a common blood-pressure/heart medicine, can help protect the brain after an acute ischemic stroke. It may improve recovery outcomes by supporting the brain’s ability to heal, especially early after stroke symptoms begin.
Langhorne, PennsylvaniaAges 18–80 - NCT07392450RecruitingPhase 2
Study of TAK-755 for adults with acute ischemic stroke
This trial tests if TAK-755 can help people who have had a moderate to severe stroke within the last 24 hours. It aims to see if the drug can improve recovery by protecting brain tissue that is still salvageable.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07362303Recruiting
Neuralert stroke monitor study for high-risk patients
This trial tests a device that monitors for stroke in adults who are at high risk after certain heart or blood vessel procedures. It could help detect a stroke early so you get treated faster.
Philadelphia, PennsylvaniaAges 22 years+ - NCT06839482Recruiting
Robot-assisted arm therapy after recent stroke
This study tests whether a robot-assisted therapy program can help people recover arm and hand movement after a recent stroke. If you had a stroke less than 3 months ago and have some weakness in your arm but can still move it a little, this trial may help you regain function.
Elkins Park, PennsylvaniaAges 18–85 - NCT06758505Recruiting
Stroke recovery study: social activities after stroke
This study tests a rehabilitation program to help people who have had a stroke get back to the social activities they enjoyed before. If you have trouble joining in activities with family or friends, this program may help you reconnect.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06682429Recruiting
Home rehab program after stroke
This study tests a home-based therapy program delivered by video calls to help people recovering from a stroke improve arm function. It is designed for those with moderate arm weakness about 4 months after their stroke.
Elkins Park, PennsylvaniaAges 18–80 - NCT06530693Recruiting
Improving emergency stroke care in the ambulance
This study looks at how emergency medical teams can better help people with stroke or mini-stroke symptoms. It aims to improve the way stroke care is started in the ambulance.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06458153Recruiting
Imaging speech after cerebellar stroke
This study uses brain scans to understand how the brain controls speech in people who have had a cerebellar stroke. It is looking for both stroke survivors and healthy volunteers to compare.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06368193Recruiting
Neuralert Stroke Monitor Pilot Study
This pilot study tests a new stroke-detection device for patients at high risk of stroke while in the hospital, especially after heart or blood vessel surgery. The device monitors for signs of stroke so doctors can respond quickly.
Philadelphia, PennsylvaniaAges 22 years+ - NCT06303869Recruiting
Deep brain stimulation for speech after stroke
This study tests if deep brain stimulation (a small device implanted in the brain) can improve speech and arm movement after a stroke that affected the deeper parts of the brain. It is designed for people who have trouble speaking clearly (dysarthria) from their stroke.
Pittsburgh, PennsylvaniaAges 18–75 - NCT05983757Recruiting
Clot retrieval for smaller brain artery strokes
This trial tests if removing clots from smaller arteries in the brain (not the main ones) helps people who had a stroke and can't get standard clot-busting medicine. It compares clot removal to usual care for strokes caused by these medium-sized vessel blockages.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05948566RecruitingPhase 2
Improving response to stroke treatment with an antibody drug
This Phase 2 trial tests an antibody treatment (TS23) given to people with a suspected acute ischemic stroke to improve how well they respond to stroke care. You may qualify if your stroke scan shows the right pattern of injured brain tissue and if the study drug can be given within a short time window after symptoms start.
Bethlehem, PennsylvaniaAges 18 years+ - NCT05611242RecruitingPhase 3
Thrombectomy for acute stroke caused by blocked neck and brain arteries
This Phase 3 trial studies whether removing a clot using a catheter (endovascular thrombectomy) works better for certain types of acute ischemic stroke. It focuses on people with a blocked neck artery plus a blockage in the brain, and who can’t get or didn’t respond to IV clot-busting medicine.
Pittsburgh, PennsylvaniaAges 18–79 - NCT04994756Recruiting
Stroke and brain blood-vessel procedure registry study
This study collects information from people who undergo a procedure for a problem in brain or blood vessels (such as stroke-related vessel blockage). It does not test a new drug; it helps doctors understand outcomes and care patterns after these procedures.
Pittsburgh, PennsylvaniaAges 1–120 - NCT04897334Recruiting
Brain stimulation plus rehab to improve thinking after stroke
This study tests whether a noninvasive brain stimulation treatment, combined with rehabilitation, can improve thinking and other “neurocognition” problems after a recent stroke. It may help people whose thinking has been affected by stroke within the past month.
Philadelphia, PennsylvaniaAges 18–90
Stroke trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting stroke studies listed above.
- University of Pittsburgh · 5 studies
- UPMC Presbyterian Hospital · 3 studies
- Hospital of the University of Pennsylvania · 2 studies
- Penn State Health Milton S. Hershey Medical Center · 2 studies
- The Hospital of the University of Pennsylvania · 2 studies
- University of Pittsburgh Medical Center · 2 studies
- 3401 N Broad street
- Alleghany Hospital
What taking part in a stroke study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Stroke trials in other states
Common questions
- Are there stroke clinical trials in Pennsylvania?
- Yes. We're currently tracking 54 recruiting stroke studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a stroke study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a stroke trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New stroke studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.