Clinical trials
Therapy clinical trials
Below are recruiting therapy clinical trials, each written for real people, not researchers. We’re tracking 7,377 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04603209Recruiting
Check-in registry for radiation during breast-conserving surgery
This registry study tracks people with early-stage, single-area breast cancer to understand outcomes when radiation is given during breast-conserving surgery. It may help doctors improve treatment planning for patients like you.
Santa Monica, CaliforniaAges 18 years+ - NCT04606459Recruiting
Device trial for hard-to-treat heart chest pain from small vessels
This trial tests whether a small pressure-reducing device placed in a heart vein (the coronary sinus) can reduce symptoms in people with ongoing chest pain from tiny blood vessel problems. It is for angina that has not improved despite standard heart medicines, and only if special heart tests show reversible reduced blood flow.
Mainz, Rhineland-PalatinateAges 18–85 - NCT04608357Recruiting
Testing digital patient avatars to guide treatment for metastatic breast cancer
This study tests whether a computer “avatar” made from your health information can help choose the best systemic therapy (medications that treat cancer throughout the body) for metastatic breast cancer. You may be asked to provide a tissue sample (biopsy) so the team can build and guide the treatment plan.
Toronto, OntarioAges 18 years+ - NCT04609709Recruiting
Physical therapy plus electrical dry needling for tension headaches
This trial tests whether specific physical therapy treatments—exercise, manual soft-tissue work, mobilization, and electrical dry needling/TENS—can reduce tension-type headaches. It may help if your headaches happen often and fit the trial’s “frequent” or “chronic” pattern.
Fort Wayne, IndianaAges 18–65 - NCT04616209RecruitingPhase 1/Phase 2
Donor immune cell therapy for advanced lung cancer
This early-phase study tests immune cells given from a matched donor to treat advanced non-small-cell lung cancer. It aims to see how safe the treatment is and whether it can help control the cancer.
TaipeiAges 20–70 - NCT04617756RecruitingPhase 2
Durvalumab plus chemo before surgery for high-risk upper urinary tract cancer
This trial studies whether durvalumab (an immunotherapy) given with chemotherapy before surgery can improve outcomes for people with high-risk cancer in the kidney pelvis or ureter. It is mainly looking at safety and effectiveness in shrinking or controlling the cancer before treatment continues.
Paris, Paris Cx 20Ages 18 years+ - NCT04617717Recruiting
Personalized treatment for abnormal heartbeats needing ablation
This trial studies a customized treatment plan for people who have premature ventricular beats (PVCs) and have been referred for a procedure called PVC ablation. It may help doctors choose the best approach for stopping these extra heartbeats.
OsloAges 18–90 - NCT04622423Recruiting
Advanced therapies for colon or pancreas liver metastases
This study tests advanced treatments for cancer that has spread to the liver, either from colon cancer or pancreatic cancer. It may help by targeting liver tumors using treatment plans and, for some participants, liver tissue samples.
Milan, MilanAges 18 years+ - NCT04626050Recruiting
PTSD and stress support study for healthcare workers
This study looks at psychological distress, including post-traumatic stress disorder (PTSD), in healthcare workers after work-related trauma. You may be eligible if you are an adult healthcare worker with PTSD (and otherwise stable) who can complete regular study check-ins.
New York, New YorkAges 18 years+ - NCT04626674RecruitingPhase 1
Gene therapy safety study for non-ambulatory Duchenne
This Phase 1 trial studies a one-time gene therapy treatment (SRP-9001) to see if it is safe and whether it can produce the needed gene activity in people with Duchenne muscular dystrophy (DMD) who are not walking. It may help researchers understand whether this approach could be useful for DMD patients, especially in later stages.
Little Rock, ArkansasAges 2 years+ - NCT04630496Recruiting
Walk Test Before Lung Surgery for Older Adults
This study is looking at a “walk and movement” challenge for older adults preparing for thoracic (chest) surgery. It may help the team understand mobility and support safer care before surgery.
Boston, MassachusettsAges 65 years+ - NCT04632628Recruiting
Online sleep coaching for insomnia in dementia caregivers
This trial tests an online form of cognitive behavioral therapy (a structured skills-based program) to improve insomnia for people caring for someone with dementia. It may help reduce trouble falling asleep, staying asleep, or waking too early.
Columbia, MissouriAges 18 years+ - NCT04636710Recruiting
Treatment approach study for stage III inflammatory breast cancer
This study looks at how to best plan local treatments (like surgery and/or radiation) for people with stage III inflammatory breast cancer. It may help doctors refine care plans for this aggressive subtype by studying how patients are treated and what outcomes they have.
Boston, MassachusettsAges 18 years+ - NCT04641936Recruiting
Urine tests to predict response to immunotherapy in bladder cancer
This study uses urine “omics” tests (detailed lab patterns from urine) to predict whether immunotherapy will work for people with metastatic urothelial (bladder/urinary tract) cancer. It may help doctors choose the right treatment sooner by identifying who is more likely to benefit.
TaipeiAges 20 years+ - NCT04647656Recruiting
Hyperbaric oxygen for lingering post-COVID brain fog
This study tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can improve long-lasting post-COVID problems with thinking and memory. It may help if your brain symptoms have lasted at least 3 months and affect your daily life.
ẔerifinAges 18 years+ - NCT04648462Recruiting
Proton therapy planning for certain brain tumors
This study builds and tests how proton therapy planning could better protect the brain compared with standard radiation (photon therapy) for adults with certain brain tumors. It may help reduce radiation to sensitive areas like the hippocampus, with the goal of better long-term brain function.
Maastricht, LimburgAges 18 years+ - NCT04652908RecruitingPhase 1/Phase 2
Cell therapy given during pregnancy to repair spina bifida
This trial studies a cell-based treatment given during fetal surgery to help repair myelomeningocele (spina bifida) before birth. It aims to improve outcomes for the baby by supporting “in utero” repair, but you must meet strict pregnancy and health criteria to be considered.
Sacramento, CaliforniaAges 4 months–6 months - NCT04655066Recruiting
Questionnaire study for pelvic floor symptoms during cancer treatment
This study asks people with breast or gynecologic cancer who are receiving cancer treatment to complete a validated questionnaire about how their pelvic floor feels. The goal is to better understand pelvic floor function and symptoms during systemic (whole-body) cancer therapy, which may help future care.
WiesbadenAges 18 years+ - NCT04657861RecruitingEarly Phase 1
BCMA/TACI CAR-T for relapsed or refractory multiple myeloma
This early-phase study tests a CAR-T cell treatment made to target BCMA and TACI proteins in multiple myeloma. It may help people whose myeloma has come back or did not respond to prior treatments, especially after certain prior therapies.
Hangzhou, ZhejiangAges 18–75 - NCT04662723RecruitingPhase 4
Personalized treatment for IgA kidney disease
This trial tests whether choosing treatment based on your personal kidney findings can improve outcomes in adults with IgA nephropathy (IgAN). It may help by matching therapy to the type and severity of kidney damage seen on biopsy.
Bari, BAAges 18 years+ - NCT04662970Recruiting
Imaging after a heart device to optimize pacing settings
This study uses a heart MRI (a special scan) to better map the heart’s electrical activity, with the goal of fine-tuning settings on your implanted pacing device. It’s meant to improve how well the device coordinates your heartbeat.
Innsbruck, TyrolAges 18 years+ - NCT04663399Recruiting
Study immune changes after stroke treatment
This study looks at how the body’s immune system responds after an acute ischemic stroke that may be treated with a procedure called mechanical thrombectomy. It may help doctors understand what immune changes happen after treatment and improve future care.
Paris, ParisAges 18 years+ - NCT04664946Recruiting
Intra-arterial treatment for stroke when no reperfusion was given
This trial tests an “intra-arterial” approach (a treatment delivered through an artery to the brain) for people with ischemic stroke who were not given clot-busting therapy or a clot-removal procedure. It aims to improve neurological recovery when there wasn’t reperfusion therapy, including in cases where symptoms worsen soon after stroke.
ShenyangAges 18 years+ - NCT04664933Recruiting
Study to protect the brain during clot-removal stroke treatment
This trial tests a brain-protective approach given through an artery during treatment for an acute ischemic stroke when clot removal (endovascular therapy) is planned. It may help reduce brain injury related to the stroke and procedure.
ShenyangAges 18 years+
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Common questions
- Are there clinical trials for therapy?
- Yes. Clin2 currently lists 7,377 recruiting therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.