Clinical trials
Thoracic clinical trials
Below are recruiting thoracic clinical trials, each written for real people, not researchers. We’re tracking 308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05313191Recruiting
Proton therapy for tumors after prior radiation
This study looks at whether a type of proton beam treatment can be given safely and effectively to tumors that have already been treated with radiation before. It may help people whose tumors came back or persisted after earlier radiation, using a specific proton method called pencil beam scanning.
New York, New YorkAges 18 years+ - NCT05215548RecruitingPhase 2
Surgery plus targeted therapy for advanced EGFR-mutated lung cancer
This trial tests whether removing the main lung tumor with surgery, combined with an EGFR-targeted pill, can help people with stage IV lung cancer that has a specific EGFR mutation. The goal is to improve outcomes compared with medication alone.
TaipeiAges 20 years+ - NCT05170815Recruiting
Spine Device Registry for Adults Getting Commercial Devices
This study is a registry that collects information about adults who use specific, commercially available spine devices. It may help doctors understand how these devices are used in real-world care and what outcomes look like over time.
LyonAges 18 years+ - NCT04871412RecruitingPhase 3
Surgery care program for lung or upper GI cancer patients
This trial tests an “integrative” support program around the time of cancer surgery to see if it improves care and outcomes for people having surgery for lung, stomach, or esophagus cancer. It may help by adding extra structured support during the peri-operative (around-surgery) period.
Ottawa, OntarioAges 18 years+ - NCT03746964Recruiting
MRI study of the heart’s aorta before planned surgery
This study uses a special MRI scan to measure how the ascending aorta (a large blood vessel) moves and behaves before planned surgery. It may help doctors better understand the mechanics of an aortic aneurysm and improve future surgical planning.
DijonAges 18 years+ - NCT04770571Enrolling by invitation
Study of posterior neck and upper-back spine fixation systems
This trial studies specific surgical hardware used to stabilize the back of the neck and upper back during spine surgery. It may help surgeons compare outcomes for people needing fixation for trauma, instability, failed prior fusion, tumors, or certain degenerative conditions.
Orange, CaliforniaAges 18 years+ - NCT04615013RecruitingPhase 1
NBTXR3 with chemoradiation for esophageal cancer treatment
This early-phase study tests adding NBTXR3 (a special treatment given into the tumor) to standard chemotherapy and radiation for esophageal cancer. The goal is to see if it can improve cancer control and to learn about safety and dosing.
Houston, TexasAges 18 years+ - NCT04369599Enrolling by invitation
Test chest vibration during ventilation for severe lung failure
This study looks at whether a special chest “vest” and related lung measurements can improve breathing in people with sudden severe lung failure who need a breathing machine. You may be eligible if you have ARDS and can safely use the vest during mechanical ventilation.
Atlanta, GeorgiaAges 18 years+ - NCT04170946RecruitingPhase 1
Talazoparib plus chest radiation after extensive small-cell lung cancer
This Phase 1 trial tests whether the medicine talazopib, given along with chest radiation, can better control extensive-stage small-cell lung cancer after initial chemotherapy. It is for people whose cancer has not worsened after finishing standard chemotherapy.
Toronto, OntarioAges 18 years+ - NCT04067830RecruitingPhase 2
Breathing muscle training before lung surgery to prevent complications
This trial tests whether training your breathing muscles before lung surgery can reduce lung problems after surgery in people with stage I to IIIb lung cancer. It may help improve breathing and lower the chance of post-surgery lung complications.
Buffalo, New YorkAges 18 years+ - NCT04005976Recruiting
Genetic study for inherited aortic disease
This trial is for people with inherited (family-run) aortic enlargement or aneurysm caused by a specific DNA gene change. It uses genetic information to guide more precise care, which may help tailor monitoring and treatment for you and your family.
Newport Beach, CaliforniaAges Any age - NCT03872661RecruitingPhase 2
New lung cancer medicines before surgery for unresectable stage III
This Phase 2 trial tests a combination of IBI308 plus bevacizumab and pemetrexed/carboplatin given before surgery, aiming to shrink or control unresectable stage III non-small cell lung cancer. It may help some people become eligible for surgery and improve outcomes, while also testing safety and effectiveness.
Guangzhou, GuangdongAges 18–75 - NCT03715517Recruiting
Spinal anesthesia to improve recovery after liver surgery
This trial studies whether using spinal/epidural anesthesia during liver tumor removal surgery can help people recover better and with less pain. It compares this approach to standard general anesthesia care to see if recovery is smoother.
Winnipeg, ManitobaAges 18 years+ - NCT03609580RecruitingPhase 1/Phase 2
Testing Flomax to prevent urine retention after chest surgery
This study looks at whether starting Flomax around the time of thoracic (chest) surgery can help prevent a painful problem called urinary retention (not being able to pee after surgery). You might benefit if you’re at risk of not urinating after your operation and can safely take Flomax.
Hackensack, New JerseyAges 50 years+ - NCT03209674Recruiting
Registry tracking outcomes after heart and chest surgery
This is a registry that collects information from people who have heart or chest (thoracic) surgery. It may help doctors understand what improves outcomes after surgery, but it usually does not test a new drug.
Neuilly-sur-Seine, Île-de-France RegionAges Any age - NCT02423070Recruiting
Study how donor genetic material behaves after lung or heart transplant
This study looks at how transplanted genetic material (DNA) changes and settles in the body after lung or heart transplant. It may help doctors understand transplant healing and improve future care for transplant recipients and candidates.
Phoenix, ArizonaAges 14–80 - NCT02266719Enrolling by invitation
Fenestrated branched stents for complex aortic aneurysms and safety
This trial studies a specialized endovascular (through-the-vessel) repair using fenestrated and branched stents to treat complex aortic aneurysms and related dissections. It aims to track clinical outcomes and how much radiation exposure is used during the procedure to improve safety.
Atlanta, GeorgiaAges 18 years+ - NCT02095808Recruiting
Testing blood and body markers in lung and chest cancers
This study looks at “biomarkers,” which are measurable signs in the body (often in blood or samples), in people with lung or other chest cancers. It may help researchers better understand these cancers and improve how they’re diagnosed or tracked.
Dallas, TexasAges 18 years+ - NCT01874197Recruiting
Studying branched stent grafts for complex aortic aneurysms
This trial tests a special stent graft to repair a thoracoabdominal aortic aneurysm (a bulge in the main artery in your chest and belly). It is for people whose aneurysm is too risky to treat with open surgery and who cannot use standard endovascular grafts.
Seattle, WashingtonAges 18 years+ - NCT01385722Enrolling by invitation
Molecular testing for cancers in the chest
This study looks at the genetic changes (molecular analysis) in certain cancers of the chest. It may help doctors learn more about what drives these cancers and how they might be diagnosed or treated in the future.
Stanford, CaliforniaAges 18 years+
Hear when a new Thoracic trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for thoracic?
- Yes. Clin2 currently lists 308 recruiting thoracic studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a thoracic trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a thoracic trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.