Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 942 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06916806RecruitingPhase 1
Study of AZD5492 for lupus, myositis, or rheumatoid arthritis
This trial tests an investigational drug called AZD5492 for people with active lupus, inflammatory myositis, or rheumatoid arthritis who haven't responded well to other treatments. It aims to see if the drug is safe and how it works in the body.
Anniston, AlabamaAges 18–70 - NCT06898450RecruitingPhase 1/Phase 2
Study of new drug NDI-219216 for advanced solid tumors
This study tests a new drug called NDI-219216 for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if it is safe and can help shrink or control the cancer.
Los Angeles, CaliforniaAges 18–99 - NCT06895499RecruitingPhase 1/Phase 2
Testing a new drug for hidradenitis suppurativa
This trial tests a new medicine called HB0043 for people with moderate to severe hidradenitis suppurativa (a skin condition causing painful lumps). It aims to see if the drug is safe and helps reduce symptoms.
Jinan, ShandongAges 18 years+ - NCT06897930RecruitingPhase 1/Phase 2
Testing a new drug for adults with lupus
This trial tests an investigational drug called AZD0120 in adults with lupus that hasn't improved with standard treatments. The goal is to see if it's safe and works well for people with lupus-related organ problems.
San Francisco, CaliforniaAges 18–70 - NCT06894875Recruiting
Lentil protein's effect on blood pressure and exercise
This trial tests a lentil protein supplement to see if it helps control blood pressure, improve blood vessel function, and boost exercise performance. You may be able to join if you're a healthy, active adult aged 18-45.
Melbourne, VictoriaAges 18–45 - NCT06884865RecruitingPhase 2
Study of an experimental knee injection for osteoarthritis pain
This study tests a new investigational medicine injected into the knee to see if it is safe and tolerable for people with painful knee osteoarthritis. It may help reduce pain and improve knee function.
Birmingham, AlabamaAges 45–80 - NCT06884618RecruitingPhase 1
Study of a new drug for advanced solid tumors with RAS mutations
This trial is testing an experimental drug for people whose cancer has spread and has a specific gene change called RAS. The study aims to see if the drug is safe and helps shrink tumors.
Duarte, CaliforniaAges 18 years+ - NCT06889168RecruitingPhase 1
Long-term safety of imatinib for LAM
This study tests the long-term safety and tolerability of the drug imatinib in women with LAM, a rare lung disease that causes cysts. It may help stabilize lung function over time.
New York, New YorkAges 18–64 - NCT06888830RecruitingPhase 1/Phase 2
Study of JS212 for advanced solid tumors
This trial tests a new drug called JS212 for people with advanced solid tumors that have not responded to other treatments. The goal is to see if it is safe and if it can help shrink tumors.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT04423874Recruiting
Tests how unpleasant sounds change pain tolerance
This study tests whether hearing unpleasant, non-verbal sounds changes how much pain you can tolerate. It may help researchers understand how stress and sound affect pain experiences.
Saint-EtienneAges 18–60 - NCT06876090Recruiting
Sarcopenia study in women with gestational diabetes
This trial looks at muscle health (sarcopenia) in women who had gestational diabetes during pregnancy. It aims to understand how gestational diabetes might affect muscle mass and function.
ViennaAges 35 years+ - NCT06872112RecruitingPhase 1
Artesunate for pulmonary arterial hypertension safety study
This trial tests if artesunate, a malaria drug, is safe and tolerable for people with pulmonary arterial hypertension (PAH). It may offer a new treatment option for PAH patients whose symptoms persist despite using two or more standard therapies.
Stanford, CaliforniaAges 18–60 - NCT06872125RecruitingPhase 3
Testing zorevunersen for Dravet syndrome
This study tests an experimental drug called zorevunersen for people with Dravet syndrome. It aims to see if the drug can reduce seizures and improve safety.
Phoenix, ArizonaAges 2–17 - NCT06863142RecruitingPhase 1
Testing a new flu vaccine with or without adjuvant
This study tests a new investigational flu vaccine (FluMos-v2) with or without an adjuvant (ALFQ) to see how safe, tolerable, and effective it is. It may help protect against multiple flu strains.
Bethesda, MarylandAges 18–50 - NCT06858397RecruitingPhase 1/Phase 2
Study of a new drug for Fabry disease
This study tests a new investigational drug called HM15421/GC1134A for people with Fabry disease. It aims to see if the drug is safe and tolerable, and to learn how well it works. You may be eligible if you have Fabry disease with symptoms, have not had treatment for at least 6 months, and your kidneys are functioning well.
Los Angeles, CaliforniaAges 18 years+ - NCT06859333RecruitingPhase 1
Safety study of Ingavirin Forte in healthy volunteers
This trial tests how safe and tolerable different doses of Ingavirin Forte are in healthy people. It helps find the right dose for future studies.
MoscowAges 18–45 - NCT06859281RecruitingPhase 1
Safety of Grammidin throat spray in healthy adults
This trial tests the safety and how the body processes a new throat spray called Grammidin. Healthy volunteers will use the spray so researchers can see how it works and if there are any side effects.
Saint PetersburgAges 18–45 - NCT06862453RecruitingPhase 1
Safety of a new malaria vaccine in healthy adults
This study tests a new malaria vaccine in healthy adults. You will receive the vaccine and then be exposed to the malaria parasite in a controlled setting to check if the vaccine protects you.
TübingenAges 18–45 - NCT06857890RecruitingPhase 1
Safety study of Grammidin throat spray in healthy volunteers
This trial tests a new throat spray called Grammidin With Anesthetic to see if it is safe and how the body processes it. Healthy volunteers take the spray and are monitored for side effects and drug levels in the blood.
MoscowAges 18–45 - NCT06867198Recruiting
Peanuts for heart, brain, and gut health
This study tests whether eating peanuts can improve health markers like blood sugar, brain function, and digestion in adults with prediabetes (higher than normal blood sugar levels). You may qualify if you are between 20-59 years old, have prediabetes, and a BMI in the overweight to obese range.
Atlanta, GeorgiaAges 20–59 - NCT06861543RecruitingPhase 1
TMT101 for advanced pancreatic or lung cancer
This trial tests a new drug called TMT101 for people with advanced pancreatic cancer or non-small cell lung cancer who have already tried other treatments. The goal is to see if TMT101 is safe and works against the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06864598Enrolling by invitation
New immune cells to help stem cell transplant success
This trial tests whether a special type of immune cell (called CD8 regulatory precursors) can help prevent the body from rejecting a stem cell transplant from a donor. It is for patients receiving a stem cell transplant from a related donor.
Beijing, Beijing MunicipalityAges 18–60 - NCT06842966RecruitingPhase 2
Testing a new tablet for chronic gallbladder issues
This trial tests an investigational tablet for people with long-term gallbladder inflammation (chronic cholecystitis) or bile duct movement problems (biliary dyskinesia). It aims to see if the tablet reduces stomach pain and other digestive symptoms.
Engel'sAges 18–70 - NCT06844214RecruitingPhase 1/Phase 2
Gene therapy trial for myotonic dystrophy type 1
This trial tests a one-time gene therapy (SAR446268) for people with non-congenital myotonic dystrophy type 1. It aims to see if the treatment is safe and can improve muscle symptoms like stiffness and weakness.
Gainesville, FloridaAges 10–55
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 942 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.