Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 953 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06948799RecruitingPhase 1
Safety study of STSP-0902 in healthy men
This study tests a new drug called STSP-0902 to see if it is safe in healthy men. It may help men with low sperm count or poor sperm movement, but the main goal is to check for side effects.
Beijing, Beijing MunicipalityAges 18–50 - NCT06950788Recruiting
Glucose changes in cirrhosis patients around liver transplant
This study looks at how the body processes sugar (glucose) in people with cirrhosis who are waiting for a liver transplant. It aims to track changes in blood sugar control before and after transplant, which may help improve care for patients with liver disease.
Chicago, IllinoisAges 18–75 - NCT06954597RecruitingPhase 2
Testing a new cream for scleroderma finger ulcers
This study tests a new cream (TOP-N53) for digital ulcers caused by scleroderma. The cream is applied directly to the sore, and the goal is to see if it is safe and helps the ulcer heal.
BordeauxAges 18 years+ - NCT06955988RecruitingPhase 1
Safety and early results of AST2303 for advanced lung cancer
This trial tests a new oral drug, AST2303 (ABK3376), in people with advanced non-small cell lung cancer that has not responded to other treatments. It aims to see if the drug is safe and whether it can shrink tumors.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06956690RecruitingPhase 1/Phase 2
Testing HMBD-501 for HER3-positive advanced solid tumors
This trial tests a new drug, HMBD-501, for people with advanced solid tumors that have a specific protein called HER3. The goal is to see if the drug is safe and if it can help shrink or control the cancer.
La Jolla, CaliforniaAges 18 years+ - NCT06959706RecruitingPhase 1
Study of TGW101 for advanced solid tumors
This trial tests a new drug called TGW101 for people with certain advanced solid tumors that have not responded to standard treatments. The goal is to see if it is safe and may help shrink tumors.
Scottsdale, ArizonaAges 18 years+ - NCT06969430RecruitingPhase 1/Phase 2
Debio 1562M for relapsed or refractory AML
This trial tests a new drug called Debio 1562M for people with AML that has not responded to treatment or has come back. It aims to see if the drug is safe and can help fight the leukemia.
Duarte, CaliforniaAges 18 years+ - NCT06976892RecruitingPhase 1
Idetrexed and Olaparib for ovarian cancer
This trial tests two drugs, idetrexed and olaparib, in people with a type of ovarian cancer that has stopped responding to standard treatments. It aims to see if this combination can help shrink or control the cancer.
Cambridge, CambridgeshireAges 18 years+ - NCT06977269Recruiting
Brain stimulation safety study for spinal muscular atrophy
This trial tests whether a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) is safe and tolerable for people with spinal muscular atrophy (SMA). It may help improve muscle function by activating low motor neurons.
Kharkiv, Kharkiv OblastAges 12 years+ - NCT06978920RecruitingPhase 1
Stem cell therapy for Parkinson's disease
This early-stage trial tests a new stem cell treatment called NCR201 for people with Parkinson's. It aims to see if the treatment is safe and might help improve symptoms.
Hefei, AnhuiAges 40–75 - NCT06980948RecruitingPhase 1/Phase 2
Gene therapy study for nerve pain from small fiber neuropathy
This trial tests a new gene therapy called ST-503 for people with long-lasting nerve pain from small fiber neuropathy that hasn't improved with standard treatments. The study will check if the treatment is safe and tolerable.
Scottsdale, ArizonaAges 18 years+ - NCT06988670RecruitingPhase 2
Testing EXT608 for adults with hypoparathyroidism
This trial tests a new medicine called EXT608 for adults with hypoparathyroidism. It aims to see if this medicine can help manage calcium levels better than current treatments.
Buenos Aires, Buenos Aires F.D.Ages 18–65 - NCT06989840RecruitingPhase 1
Safety study of TVB-3567 for acne
This early-stage study tests a new drug called TVB-3567, which may help treat acne. It checks the drug's safety and how the body processes it, first in healthy people and then in people with moderate to severe acne.
Tempe, ArizonaAges 18–55 - NCT06994845RecruitingPhase 3
Testing iptacopan for children with IgA nephropathy
This study tests a new medicine called iptacopan to see if it helps children with IgA nephropathy (a kidney disease). Kids who join will receive the study treatment and be monitored for safety and effectiveness.
Aurora, ColoradoAges 2–18 - NCT06994897RecruitingPhase 1
Safety and dosing study of PF-07985631 in healthy adults
This study tests a new medicine called PF-07985631 in healthy adults to see how different amounts are tolerated and processed by the body. It includes specific groups for Japanese and Chinese participants.
Brussels, Bruxelles-capitale, Région deAges 18–55 - NCT06995573RecruitingPhase 1/Phase 2
Testing a new Alzheimer's drug (NSC001) for safety and early effectiveness
This study tests a new drug called NSC001 for people with mild to moderate Alzheimer's. It checks if the drug is safe and if it might help slow memory decline. You'll need a caregiver who can join you at visits and help track your progress.
Salzburg, State of SalzburgAges 50–85 - NCT06995482RecruitingPhase 1
Testing safety of KSHN001034 in healthy postmenopausal women
This study tests how safe and tolerable a new drug, KSHN001034, is in healthy women who have gone through menopause. It involves multiple doses to see how your body processes the medicine.
Miami Lakes, FloridaAges 45–60 - NCT06995820RecruitingPhase 1
Safety study of AZD1613 in healthy volunteers
This is a first-in-human trial testing an experimental drug (AZD1613) in healthy volunteers. It helps doctors see if the drug is safe, how it is processed by the body, and how the immune system reacts. The trial is designed for healthy men and women who cannot become pregnant and may require participants to be of Chinese or Japanese descent for certain groups.
Glendale, CaliforniaAges 18–50 - NCT07011511RecruitingPhase 1
Testing a new malaria drug in healthy volunteers
This trial tests a new malaria drug (MMV055), alone or with another drug (MMV371), to see if it is safe and how the body processes it. It is for healthy people who want to help find new malaria treatments.
NottinghamAges 18–60 - NCT07014007Recruiting
Testing a new moisturizer for eczema in different age groups
This study tests a new moisturizing product (RV4421B) for people with mild to moderate atopic dermatitis (eczema). Participants will use the product along with their usual steroid cream for 12 weeks to see how well it works and if it’s safe for different ages, from babies to adults.
Quatre Bornes, MauritiusAges 3 months+ - NCT07015749RecruitingPhase 1
IBI3002 for moderate to severe asthma
This trial tests a new drug called IBI3002 for people with moderate to severe asthma that isn't well controlled with standard inhalers. It aims to see if the drug is safe and tolerable when given multiple times.
Suzhou, JiangsuAges 18–65 - NCT07015762RecruitingPhase 1
Testing IBI3002 for moderate-to-severe eczema
This trial tests a new drug called IBI3002 in people with moderate-to-severe atopic dermatitis (eczema) to see if it is safe and tolerable. It may help reduce skin inflammation and itching.
Suzhou, JiangsuAges 18–65 - NCT07016802RecruitingPhase 1
Study of GenSci134 for growth hormone deficiency
This trial tests a new growth hormone treatment called GenSci134 in healthy adults and adults with growth hormone deficiency (AGHD). The goal is to see if it is safe and effective for people who need growth hormone replacement.
Beijing, Beijing MunicipalityAges 18–70 - NCT07021157RecruitingPhase 1
First-in-human study of SK-08 in healthy volunteers
This trial tests a new drug called SK-08 in healthy volunteers to see if it's safe and how the body processes it. It helps doctors find the right dose for future studies of this potential medicine.
Hangzhou, ZhejiangAges 18–45
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 953 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.