Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 942 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07684235RecruitingPhase 3
Long-term study of a weight-loss drug for trial graduates
This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.
Anniston, AlabamaAges 18–99 - NCT07681076RecruitingPhase 4
KarXT safety study with anti-nausea meds in healthy volunteers
This trial checks if adding anti-nausea drugs to a new medication (KarXT) is safe for healthy people. It involves a 3-week stay in a research center so doctors can monitor you closely.
Los Alamitos, CaliforniaAges 18–65 - NCT07682870RecruitingPhase 1/Phase 2
Study of VG2025 for advanced solid tumors
This trial tests a new drug, VG2025, given through a vein for people with advanced solid tumors that have stopped responding to standard treatments. It aims to see if the drug is safe and if it can help shrink or control the tumors.
ShanghaiAges 18–75 - NCT07673809RecruitingPhase 1/Phase 2
Gene therapy trial for Duchenne muscular dystrophy in young boys
This trial tests a gene therapy called GNR-097 for boys with Duchenne muscular dystrophy (DMD). The therapy aims to help improve muscle function, and the study will check how safe and effective it is.
MinskAges 4–9 - NCT07675590RecruitingPhase 1
Safety study of TIX100 in healthy volunteers
This study tests a new oral medication called TIX100 in healthy people to see if it is safe and how the body handles it. It is the first step in human testing, so it focuses on safety and side effects.
Chula Vista, CaliforniaAges 18–70 - NCT07677137Recruiting
Study of a new nerve stimulation device for chronic cluster headache prevention
This study is testing a new device that uses mild electrical stimulation near the back of the head to prevent cluster headaches. It is for people with chronic cluster headaches that are hard to treat with standard medicines.
Sint-NiklaasAges 22–70 - NCT07676084RecruitingPhase 4
Over-the-counter lubricating eye drops for dry eye
This study tests whether over-the-counter lubricating eye drops can improve dry eye symptoms and eye comfort. It compares the drops to no treatment to see how well they work.
Andover, MassachusettsAges 18 years+ - NCT07672756RecruitingPhase 1
Testing PL54 injection for adults with PKU
This study tests a new injection called PL54 to see if it is safe and tolerable for adults with phenylketonuria (PKU), a condition where the body cannot break down an amino acid called phenylalanine. It is designed for people with high blood phenylalanine levels and may offer a new treatment option.
Hefei, AnhuiAges 18–55 - NCT07676903RecruitingPhase 1
Study of a new drug for patients with solid tumors
This trial tests a new drug, SHR-4685, for people with solid tumors that are measurable. It aims to see if the drug is safe and how your body processes it.
North Ryde, New South WalesAges 18–75 - NCT07673120RecruitingPhase 1
Safety study of ABBV-313 in healthy adults
This study tests a new drug called ABBV-313 in healthy adults to see if it is safe and how the body handles it. You will receive either a single injection or infusion, or multiple doses, to help researchers understand its effects.
Anaheim, CaliforniaAges 18–55 - NCT07676890RecruitingPhase 1
Study of a personalized vaccine for ovarian cancer after surgery
This trial tests a personalized vaccine made from your tumor's genetic material. It is given after surgery to help your immune system recognize and attack any remaining cancer cells, with the goal of preventing the cancer from coming back.
Chengdu, SichuanAges 18–75 - NCT06167681RecruitingPhase 1/Phase 2
Cell Therapy NouvNeu001 for Parkinson's Disease
This trial tests a new cell therapy called NouvNeu001 for Parkinson's disease. It involves a one-time brain surgery to deliver the treatment, and researchers will check if it's safe and helps with symptoms.
Beijing, Beijing MunicipalityAges 50–75 - NCT06669429RecruitingPhase 1
Safety study of RS-C1001 in healthy Chinese adults
This study tests a new medication called RS-C1001 in healthy Chinese volunteers to see if it's safe and how the body processes it. The drug may help lower cholesterol, but the main goal here is to check for side effects.
BeijingAges 18–45 - NCT07668518RecruitingPhase 1/Phase 2
Study of KIT2014 for moderate to severe COPD
This trial tests a new medicine called KIT2014 in people with moderate to severe COPD. It aims to see if the drug is safe, tolerable, and helps improve breathing and COPD symptoms.
Charlestown, New South WalesAges 40–80 - NCT07670234Recruiting
Dietary Supplements and Cancer Treatment
This study looks at how dietary supplements (like vitamins and herbs) affect cancer patients who are on treatment. It checks if supplements cause side effects, change how medications work, or interact with each other.
RabatAges 18 years+ - NCT05141474RecruitingEarly Phase 1
Personalized immune cell treatment for advanced cancers after failed therapy
This trial tests a personalized therapy made from your own immune cells (TIL) picked to match your tumor’s “neoantigens,” plus standard immune-boosting medicine (including IL-2). It’s for people with advanced epithelial or immune “resistant” solid tumors whose cancer has continued growing despite available treatments.
BarcelonaAges 18 years+ - NCT06608355RecruitingPhase 1
Stem cell treatment for early-onset Parkinson's
This trial tests a new stem cell treatment called NouvNeu001 for people with early-onset Parkinson's disease. The goal is to see if it's safe and if it can help improve movement and daily life.
Wuhan, HubeiAges 18–70 - NCT07660731RecruitingPhase 1
Safety study of an experimental asthma medicine
This study tests an experimental medicine (PF-08103402) to see how well it is tolerated and how it acts in the body, in healthy adults and in people with mild-to-moderate asthma. Participation may help researchers learn if this treatment could help manage asthma symptoms.
New Haven, ConnecticutAges 18–65 - NCT07660198RecruitingPhase 3
Pneumonia vaccine catch-up study for kids and teens
This trial tests a catch-up pneumococcal vaccine for children and adolescents who may have missed some doses. It aims to see how safe and effective the vaccine is in healthy kids aged 15 months to 17 years.
Birmingham, AlabamaAges 1.3 years–17 years - NCT07658638RecruitingPhase 1
Study of a new medicine TESP-0401 in healthy people
This study tests a new medicine called TESP-0401 in healthy people to see if it is safe and how the body handles it. It is an early-stage trial, and you will stay at a clinic for part of the study.
Charlestown, Suite 301, 99 Pacific Highway,NSWAges 18–65 - NCT07662057RecruitingPhase 1
Safety study of AB102 in healthy volunteers
This trial tests a new medicine called AB102 in healthy people to see if it is safe and how the body processes it. It may help researchers understand the right dose for future studies.
GroningenAges 18–55 - NCT07654114RecruitingPhase 2
Testing CTH120 for men with Fragile X syndrome
This trial tests a new medicine called CTH120 to see if it is safe and helpful for adult men with Fragile X syndrome. You may be able to join if you meet certain health and age requirements.
Barcelona, BarcelonaAges 18–45 - NCT07646353RecruitingPhase 1
First-in-human safety study of an investigational drug in healthy adults
This study tests a new investigational drug (GSK4425689A) for the first time in humans. It is a healthy volunteer study to check the safety, side effects, and how the drug moves through the body. It may help in the future development of treatments for malaria.
ManchesterAges 18–65 - NCT07647783RecruitingPhase 1
Safety Study of SYH2072 Tablet in Healthy Adults
This is an early-stage safety study testing a new experimental tablet called SYH2072 in healthy volunteers. Researchers will give increasing doses to understand how safe it is, how your body processes it, and what effects it has.
Beijing, Beijing MunicipalityAges 18–55
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 942 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.