Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 942 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07726147RecruitingPhase 1
Testing a new allergy shot for Japanese cedar pollen
This trial tests a new allergy shot (ITI-9001) for people with Japanese cedar pollen allergy. It aims to see if the shot is safe and can reduce allergy symptoms. The study is for people who have not tried immunotherapy before.
Tokyo, Shinjuku-kuAges 18–65 - NCT05200650RecruitingPhase 1
Test gel with cisplatin injected into head and neck tumors
This trial studies an anti-cancer gel that delivers cisplatin directly into a head and neck tumor with a single injection. It mainly checks safety and side effects, and also looks for early signs that the tumor responds in people whose cancer is progressing or no longer responds to standard treatment.
JerusalemAges 18–80 - NCT07724106RecruitingPhase 1
NeoOVSV vaccine for ovarian cancer after surgery
This trial tests a personalized vaccine made from your own tumor tissue called NeoOVSV. It is meant to train your immune system to fight any remaining cancer after surgery. The vaccine is a personal treatment because it uses your tumor's unique markers.
Chengdu, SichuanAges 18–75 - NCT05942625RecruitingPhase 1
Study of an experimental drug in healthy adults
This Phase 1 trial tests how safe and tolerable an experimental medicine (HS-10390) is in healthy adults, and how the body processes it. It is not for people with an illness, but for healthy volunteers to help researchers understand the drug before future studies.
Nanjing, JiangsuAges 18–45 - NCT07717905RecruitingPhase 1/Phase 2
Testing BBT001 for chronic hives
This trial tests a new medicine called BBT001 for people with chronic spontaneous urticaria (long-lasting hives without a known cause). It aims to see if the drug is safe and helps reduce itching and hives.
Wuhu, AnhuiAges 18–75 - NCT07721597RecruitingEarly Phase 1
Testing ZP6590 in Men of Various Weights
This trial tests an experimental medication called ZP6590 given as injections. It's for men who are at a normal weight, overweight, or have obesity, and studies how safe and well-tolerated the drug is in different doses.
Neuss, North Rhine-WestphaliaAges 18–60 - NCT07710690RecruitingPhase 1
Study of NRG-103 injection for recurrent high-grade glioma
This trial tests a new injection called NRG-103 for people whose high-grade glioma (a fast-growing brain tumor) has come back after standard treatments. The goal is to see if it's safe and if it might help shrink the tumor.
ShanghaiAges 18 years+ - NCT07708779RecruitingPhase 1
Inhaled isoniazid for tuberculosis treatment
This trial tests inhaled isoniazid (medicine) given through a nebulizer to see how well it works and how safe it is. It's for people being treated for tuberculosis.
GroningenAges 18 years+ - NCT07708714RecruitingPhase 1/Phase 2
Hydroxyurea study for teens with sickle cell anemia
This study tests how well a higher dose of hydroxyurea works for teenagers with sickle cell anemia living in areas where malaria is common. It looks at safety and how the treatment affects their daily lives.
KampalaAges 11–18 - NCT06644963Recruiting
Impella heart pump study: safety and complications
This study reviews how well people tolerated the Impella heart pump during cardiogenic shock and what complications occurred. It looks at past cases from 2010 to 2022 to help doctors understand the safety of this device.
MontpellierAges 18 years+ - NCT07700056RecruitingPhase 3
Study of remibrutinib for severe itching of unknown cause
This study tests an investigational medicine (remibrutinib) for people with severe itching that has no known cause. It may help reduce the itch when moisturizers haven't worked.
Miami, FloridaAges 18 years+ - NCT07702890RecruitingPhase 1/Phase 2
Testing a new drug for obesity and type 2 diabetes
This trial tests an investigational drug called GUB-UCN2 in people who are healthy, overweight, or have type 2 diabetes. The goal is to see if the drug is safe and how the body processes it.
NeussAges 18–75 - NCT07699120Enrolling by invitationPhase 1
Testing BRC-002 safety in healthy volunteers
This trial checks how safe BRC-002 is in healthy people and how it affects the body with and without food. It helps researchers understand the right dose and any side effects.
Toronto, OntarioAges 18–55 - NCT07704840RecruitingPhase 2
Testing a new pill for post-stroke arm stiffness
This study tests an experimental pill (BMS-986368) that targets two brain chemicals to reduce muscle stiffness after a stroke. It's for people who had a stroke in the last 4 to 18 months and have moderate tightness in their elbow and wrist.
Elkins Park, PennsylvaniaAges 18–80 - NCT06390774RecruitingPhase 1
Study of SSGJ-705 for advanced cancers
This phase 1 trial tests a new targeted drug (SSGJ-705) for people with advanced solid tumors or lymphomas. Doctors will check safety and find the best dose, and there may be a chance the drug helps shrink or control the cancer.
Jinan, ShandongAges 18–75 - NCT06116045RecruitingPhase 2
Study of BZ371A for women with sexual arousal disorder
This trial tests an investigational medication, BZ371A, to see if it can help women with Female Sexual Arousal Disorder (FSAD), a condition where they have trouble getting or keeping physical signs of arousal like lubrication and warmth. The study aims to find out if BZ371A is safe, effective, and well-tolerated.
Rio de Janeiro, Rio de JaneiroAges 21–60 - NCT07697560RecruitingPhase 1
Safety of AH-008 in healthy volunteers
This trial tests a new medicine called AH-008 in healthy people to see if it's safe and how the body processes it. It is a first-in-human study with a single dose.
Salt Lake City, UtahAges 18–65 - NCT07696793RecruitingPhase 4
Simethicone colonoscopy prep for cancer screening
This trial tests a colonoscopy preparation drink that contains simethicone (a gas-relief ingredient) to see if it works better than standard prep for people who are already scheduled for a screening colonoscopy after a positive stool test. It may help make the procedure more comfortable and effective.
Barcelona, BarcelonaAges 50–69 - NCT07687303Recruiting
Ventilator modes and stomach tube tolerance in ICU patients
This study looks at how different ventilator settings affect pressure in the belly and how well patients tolerate a feeding tube. It may help doctors choose the best ventilator mode for you.
DamanhūrAges 18–60 - NCT07680764RecruitingPhase 2
Imzokitug plus pumitamig and chemo for first-line advanced lung cancer
This trial tests a new combination of drugs (imzokitug, pumitamig, and platinum-doublet chemotherapy) as a first treatment for advanced or metastatic non-small cell lung cancer that has not spread to the brain. The goal is to see if adding imzokitug makes the standard treatment work better.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07682896RecruitingPhase 2
Testing YB-101 for safety and effectiveness in Graves' disease
This trial tests an investigational drug called YB-101 for people with Graves' disease, whether or not they have thyroid eye disease. The goal is to see if the drug is safe and can help.
Gilbert, ArizonaAges 18 years+ - NCT07684235RecruitingPhase 3
Long-term study of a weight-loss drug for trial graduates
This study tests a drug called Maridebart Cafraglutide for long-term weight management in people who completed a previous related trial. It looks at how well the drug works and its safety over time.
Anniston, AlabamaAges 18–99 - NCT07682870RecruitingPhase 1/Phase 2
Study of VG2025 for advanced solid tumors
This trial tests a new drug, VG2025, given through a vein for people with advanced solid tumors that have stopped responding to standard treatments. It aims to see if the drug is safe and if it can help shrink or control the tumors.
ShanghaiAges 18–75 - NCT07684196RecruitingPhase 1
First test of ENC0653 ointment in healthy adults
This study tests a new ointment called ENC0653 in healthy adults to see if it is safe and how it works in the body. It is the first time this ointment is being tested in people, so if you are healthy and your skin is clear, you may be able to help.
Shanghai, Xuhui DistrictAges 18–55
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 942 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.