Clinical trials
Traumatic Brain Injury clinical trials
Below are recruiting traumatic brain injury clinical trials, each written for real people, not researchers. We’re tracking 362 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07849465RecruitingPhase 2
Oxygen therapy for veterans with brain injury and lasting symptoms
This study tests whether breathing high-pressure oxygen (hyperbaric oxygen therapy) can help veterans who have had a traumatic brain injury (TBI) and are dealing with ongoing issues like memory or concentration problems. It also looks at whether this treatment affects certain markers in the blood that may relate to brain health.
Boise, IdahoAges 18–75 - NCT06311604Recruiting
Inhaled sedation safety for head trauma patients
This trial tests a new way to give sedation through a breathing mask (isoflurane gas) to people with severe head injuries. It aims to see if this method is safe and may help when IV sedatives alone are not enough.
Grenoble, Choisir Une RégionAges 18 years+ - NCT07768761Recruiting
Electrical stimulation exercise for lower limb paralysis
This trial tests whether a muscle exercise program using electrical stimulation can help people with paralysis in their legs. It may improve muscle strength, blood flow, or other health benefits.
Cleveland, OhioAges 18 years+ - NCT07759063Enrolling by invitation
Self-paced walking study for stroke or brain injury survivors
This study tests a new way to help people who have had a stroke or brain injury walk with a more even step. It uses a treadmill that adjusts to your own pace, which may improve your walking symmetry.
Omaha, NebraskaAges 19–75 - NCT06005194Recruiting
Exercise therapy via telehealth for depression after brain injury
This study tests whether an exercise program delivered through video calls can help treat major depression in people who have had a traumatic brain injury. If you are at least one year past your injury and have symptoms of depression, you may be able to join.
Seattle, WashingtonAges 18–64 - NCT06627686Recruiting
Predicting successful breathing tube removal in brain injury patients
This study tests if simple breathing tests can predict whether a patient with a traumatic brain injury will successfully breathe on their own after a breathing tube is removed. The goal is to make the removal process safer.
Tanta, MahalaAges 18–65 - NCT06454591Recruiting
Using fast MRI to understand brain injury recovery
This study uses a quick MRI scan to check brain function and predict recovery after a traumatic brain injury. It may help researchers develop better ways to assess and treat TBI patients.
Calgary, AlbertaAges 18 years+ - NCT07683169Recruiting
Trauma molecular processes study
This trial studies biological processes after a traumatic brain injury. It looks at brain tissue samples from patients who need surgery to remove a brain bruise to learn more about healing and injury.
BergamoAges 18 years+ - NCT07625098RecruitingPhase 1
Social Support Program for People After Brain Injury
This study tests whether a program that helps connect people with social support can improve quality of life for adults living at home after a traumatic brain injury. You might qualify if your injury happened more than 6 months ago and you feel isolated or lack strong social connections.
St Louis, MissouriAges 18 years+ - NCT07624825Recruiting
Emotional Awareness Therapy After Brain Injury
This study tests whether a therapy focused on recognizing and understanding emotions can help people recover better after a moderate or severe traumatic brain injury (TBI). You'll participate if you're at least 6 months past your injury and struggle to identify or describe your feelings.
Edison, New JerseyAges 18 years+ - NCT05176392Recruiting
Stimulation treatment plus therapy for post-injury headaches
This study tests whether a noninvasive brain stimulation treatment combined with therapy can reduce long-lasting headaches after a mild brain injury. You might be a good candidate if your headaches started after the injury and have continued for months.
San Diego, CaliforniaAges 18–65 - NCT07614074Recruiting
Understanding Recovery from Coma and Unconsciousness
This study follows patients who have been in a coma (deep unconsciousness) for at least 24 hours due to a brain injury. Researchers will track how patients recover over time to better understand which factors help predict who will wake up and how well they'll recover.
San Francisco, CaliforniaAges 18 years+ - NCT06473987Recruiting
Virtual reality training for better walking after brain injury
This trial tests a virtual reality program that combines thinking and walking exercises to help improve your balance and walking speed. It may be a good fit if you have a traumatic brain injury and walk more slowly than usual.
West Orange, New JerseyAges 18–65 - NCT07601841Recruiting
Light therapy to improve sleep after brain injury
This study tests whether light therapy can help people sleep better after a traumatic brain injury (TBI). Researchers will use MRI brain scans and sleep tracking to see if light therapy changes how your brain clears toxins during sleep.
Portland, OregonAges 18–89 - NCT07572734Recruiting
Breathing exercises to help after a concussion in teens
This study tests whether special breathing exercises can help the nervous system recover better after a concussion. Kids ages 9–18 who come to the emergency room within 3 days of a concussion may qualify if they have symptoms like dizziness, nausea, tiredness, confusion, anxiety, or sleep problems.
Montreal, QuebecAges 9–18 - NCT07569354Recruiting
Recovery in Older Adults After Mild Head Injury
This study follows older adults (65+) who had a mild traumatic brain injury (concussion) to understand how they recover over time. Researchers want to learn what helps seniors bounce back and stay active after a head injury.
Baltimore, MarylandAges 65 years+ - NCT05589064Recruiting
Diet and nutrition program for lingering concussion symptoms
This study tests whether a dietary and nutrition intervention can improve symptoms that linger after a concussion. It may help people whose post-concussion symptoms have lasted a short to medium time (at least 2 weeks).
Moncton, New BrunswickAges 16 years+ - NCT07549997RecruitingPhase 1
Social Participation Recovery Program After Brain Injury
This study tests whether a group program can help people who've had a traumatic brain injury (TBI) get back to social activities they enjoyed before their injury. You'll work with others and learn strategies to re-engage with friends, family, and community.
St Louis, MissouriAges 18 years+ - NCT07521384Enrolling by invitation
Real-World Study of Intranasal Cell Therapy for Brain Injuries
This study follows people who receive intranasal stem cell or exosome therapy (tiny packages from special cells) for brain or neurological conditions like stroke, brain injury, or cerebral palsy. Researchers track how well the treatment works by measuring inflammation markers in the blood and monitoring clinical improvements over time.
Monterrey, Nuevo LeónAges 4–80 - NCT07493096Recruiting
Intensive therapy program for children with brain-based conditions
This trial tests an intensive therapy program designed to help children with brain-based conditions like cerebral palsy or autism improve their skills in movement, thinking, and daily activities. The program runs for 2 weeks with daily sessions, and researchers will check for changes in your child's abilities.
The Woodlands, TexasAges 4–12 - NCT05943756Recruiting
Well-being program for adults living with moderate to severe brain injury
This trial tests whether a well-being program can improve quality of life in adults with moderate to severe traumatic brain injury (TBI) more than a year after the injury. If you meet the language and medical-history requirements, you may be invited to join and complete program sessions and screening.
East Hanover, New JerseyAges 18 years+ - NCT07466589Recruiting
Electric stimulation for dizziness after concussion
This trial tests if a portable electric stimulation device can help improve balance and reduce dizziness in people recovering from a concussion. If you have had ongoing imbalance for at least 4-6 weeks, this study may help you feel steadier.
Ann Arbor, MichiganAges 18–55 - NCT06792877Recruiting
Mindfulness for thinking in early Alzheimer's
This study tests if mindfulness training can help protect thinking and memory in early-stage Alzheimer's disease. It compares mindfulness to other activities to see if it slows down memory loss.
Boston, MassachusettsAges 50–100 - NCT07410624Recruiting
Kidney function in brain injury patients
This trial measures how quickly the kidneys clear drugs in patients with serious brain conditions like stroke or meningitis. It may help doctors adjust medicine doses for better treatment.
Lexington, KentuckyAges 18–85
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Common questions
- Are there clinical trials for traumatic brain injury?
- Yes. Clin2 currently lists 362 recruiting traumatic brain injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a traumatic brain injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a traumatic brain injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.