Clinical trials · Chicago, IL
Type 1 diabetes clinical trials in Chicago
We’re tracking 42 recruiting type 1 diabetes studies with a site in or near Chicago — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Chicago
- NCT07076199RecruitingPhase 3
Weekly vs daily insulin for type 1 diabetes
This study tests a new once-weekly insulin (icodec) against a standard daily insulin (glargine), both taken with mealtime insulin. It aims to see which works better to control blood sugar in adults with type 1 diabetes.
Chicago, IllinoisAges 18 years+ - NCT07228117Recruiting
Testing a new automated insulin pump for people with diabetes
This study tests a new automated insulin delivery system (a pump that helps manage blood sugar) in children and adults with diabetes. It aims to see if the system is safe and easy to use in daily life.
Chicago, IllinoisAges 7–85 - NCT06915831Recruiting
Type 1 diabetes and sleep apnea study
This study looks at how sleep apnea affects blood sugar control in adults with type 1 diabetes. It may help researchers understand if treating sleep apnea improves diabetes management.
Chicago, IllinoisAges 18–50 - NCT05762107RecruitingPhase 2
Drug ZT-01 to reduce low blood sugar at night
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
Chicago, IllinoisAges 18–75 - NCT06624046Recruiting
Sleep and glucose study for type 1 diabetes
This study looks at how sleep affects blood sugar and heart health in people with type 1 diabetes. If you have irregular sleep and want to improve it, researchers will test a wearable device and sleep coaching.
Chicago, IllinoisAges 18–50 - NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Chicago, IllinoisAges 18–75 - NCT07662109RecruitingPhase 3
Testing a new combo pill for type 2 diabetes
This study tests if a new medicine (elecoglipron) combined with dapagliflozin is safe and works better for adults with type 2 diabetes that isn't well controlled by diet or other medications.
Chicago, IllinoisAges 18 years+ - NCT04334707Recruiting
Study kidney damage in people with long-term diabetes
This study is looking at different kidney health patterns in people with diabetes, especially diabetic kidney disease and people who have not developed kidney damage despite long-term diabetes. It may help researchers understand why kidney problems happen—and what protective factors might prevent them.
Chicago, IllinoisAges 18 years+ - NCT03585153Enrolling by invitation
Pancreas imaging study in people with type 1 diabetes
This study takes pictures of the pancreas in children and teens (and likely adults) with type 1 diabetes soon after diagnosis. The goal is to learn more about how the pancreas changes with diabetes, which may help future care.
Chicago, IllinoisAges 8 years+ - NCT04786262RecruitingPhase 3
Study of VX-880 for long-standing type 1 diabetes
This Phase 3 trial tests how safe, tolerable, and effective VX-880 is for people with type 1 diabetes who have had it for many years. It may help reduce problems related to blood sugar swings, especially severe low blood sugar episodes.
Chicago, IllinoisAges 18–65 - NCT05145374Recruiting
Testing an insulin pump system for exercise and stress swings
This study tests a smarter (automated) insulin pump approach to help prevent blood sugar problems when you do physical activity or when you’re under sudden stress. It may help people with type 1 diabetes use insulin more safely during real-life changes.
Chicago, IllinoisAges 20–60 - NCT06112418Recruiting
Personalized vs standard care to prevent heart attacks
This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.
Chicago, IllinoisAges 55 years+ - NCT07024823RecruitingPhase 1
Safety study of AZD4248 in healthy people and those with kidney disease and diabetes
This trial tests an experimental drug called AZD4248 to see if it's safe for healthy people and for people with chronic kidney disease and type 2 diabetes. It also checks if a home device can accurately measure kidney function.
Chicago, IllinoisAges 18–75 - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Chicago, IllinoisAges 18 years+ - NCT07676565Recruiting
Adding new drugs to insulin for type 1 diabetes
This study tests whether adding certain diabetes pills (GLP-1 receptor agonists or SGLT inhibitors) to insulin is safe and helpful for adults with type 1 diabetes. Doctors will check your glucose monitor data to see how well this works.
Chicago, IllinoisAges 18 years+ - NCT06481904Recruiting
Registry for stage 2 type 1 diabetes
This study tracks people with stage 2 type 1 diabetes to see how they do over time, either with or without treatment with a drug called TZIELD. It helps doctors learn more about the disease and the effects of this treatment.
Chicago, IllinoisAges Any age - NCT01630850Recruiting
Islet cell transplant for brittle type 1 diabetes
This trial studies whether transplanting insulin-producing islet cells can improve blood sugar control and reduce severe low blood sugar in people with “brittle” type 1 diabetes. It’s meant for adults with long-standing insulin dependence and troublesome, hard-to-control hypoglycemia.
Chicago, IllinoisAges 18–70 - NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Chicago, IllinoisAges 12–35 - NCT06964087RecruitingPhase 2
Testing OPT101 for type 1 diabetes
This trial tests an investigational drug called OPT101 in people with type 1 diabetes. It aims to see how the drug works in the body and whether it can help preserve insulin production, especially in those diagnosed recently or within the last 20 years.
Chicago, IllinoisAges 18–50 - NCT06575426RecruitingPhase 1/Phase 2
Pig pancreatic cell transplant for type 1 diabetes
This trial tests a new treatment made from pig pancreatic cells (called OPF-310) that are placed under the skin to help control blood sugar in people with type 1 diabetes. It is for those whose diabetes is difficult to manage and who have dangerous low blood sugar episodes.
Chicago, IllinoisAges 35–70 - NCT07091318RecruitingEarly Phase 1
CBT for insomnia in type 1 diabetes
This study tests whether cognitive behavioral therapy for insomnia (CBTi) can improve sleep in people with type 1 diabetes. It may help those who have poor sleep quality and use a continuous glucose monitor.
Chicago, IllinoisAges 18–65 - NCT07296484RecruitingPhase 2
Clofutriben for hard-to-control type 2 diabetes
This trial tests a new medication, clofutriben, for people with hard-to-control type 2 diabetes who might also have mild excess of a stress hormone called cortisol. It aims to see if the drug can help lower blood sugar and improve diabetes management.
Chicago, IllinoisAges 18 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Chicago, IllinoisAges 18 years+ - NCT01241864RecruitingPhase 2
Islet transplant for type 1 diabetes after kidney transplant
This trial tests whether transplanting insulin-producing “islet” cells can better control blood sugar in people who have already received a kidney transplant. It’s mainly for adults with type 1 diabetes whose body is no longer making enough insulin, while they are on kidney-transplant medicines.
Chicago, IllinoisAges 18–68
Hear when a new Type 1 diabetes trial opens near Chicago, IL
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Type 1 diabetes trials in other cities
Where these studies are running near Chicago
Institutions with a site for the recruiting type 1 diabetes studies listed above.
- University of Chicago · 9 studies
- Northwestern University · 7 studies
- University of Illinois · 5 studies
- Research Site · 3 studies
- Accellacare - Duly Health and Care
- Accellacare of Duly Health and Care
- Cedar Crosse Research Center
- Chicago Clinical Research Institute INC
What taking part in a type 1 diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting type 1 diabetes studies in Illinois.
Common questions
- Are there type 1 diabetes clinical trials near Chicago?
- Yes. We're currently tracking 42 recruiting type 1 diabetes studies with a site near Chicago, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a type 1 diabetes study near Chicago?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Chicago to take part?
- Not necessarily. These studies have a site near Chicago, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a type 1 diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New type 1 diabetes studies open near Chicago regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.