Type 1 diabetes clinical trials in Texas

Icovamenib for type 2 diabetes with Ozempic

This trial tests an investigational pill called icovamenib for people with type 2 diabetes who are already on Ozempic but still have high blood sugar. The goal is to see if adding icovamenib helps lower blood sugar more safely.

Improving Kidney Care for People with Type 2 Diabetes

This study tests a program to help primary care doctors better screen and manage kidney problems in people with type 2 diabetes. It aims to see if using recommended medicines can slow kidney disease and improve health.

Preventing kidney and heart damage in type 2 diabetes

This study tests whether diabetes medicines can help prevent worsening heart and kidney problems in people with type 2 diabetes. You’ll be assigned by chance to one of these medicine types, and your other care will be adjusted for safety.

Biomarker and health marker study in myotonic dystrophy type 1

This study measures physical and lab “health markers” in people with myotonic dystrophy type 1 (DM1) to better understand how the disease changes over time. Some participants may also have a muscle biopsy to study tissue differences.

Long-term safety study of del-desiran for DM1

This study tests whether the drug del-desiran continues to be safe and effective for people with DM1 (myotonic dystrophy type 1) after they complete an earlier study. You'll receive the drug and have regular check-ups to see how you're doing.

Study of a new pill for weight loss and diabetes

This study tests a new daily pill (aleniglipron) to help adults with excess weight and type 2 diabetes lose weight and improve blood sugar control. It may be a good fit if you have a BMI of 27 or higher and your diabetes is managed with A1c between 6.5% and 10%.

Study of prediabetes with abnormal sugars and medicines

This study looks at adults with prediabetes—specifically abnormal fasting and/or 2-hour blood sugar tests—to see whether a treatment helps improve sugar control. You may also be compared with people who have normal blood sugar (the control group).

Lean Beef as Part of a Healthy Meal Plan in Adolescents With Polycystic Ovary Syndrome (PCOS)/Polyendocrine Metabolic Ovarian Syndrome (PMOS)

Measuring liver energy use in people with diabetes and fatty liver disease

This study looks at how the liver uses energy (mitochondria) in people with type 2 diabetes and fatty liver disease. By understanding this, researchers may find better ways to treat liver problems.

Study of enicepatide for weight loss in obesity or overweight

This study tests a new injectable medication called enicepatide for people with obesity or overweight who have not been able to lose weight through diet and exercise alone. It may help you lose weight and improve health conditions linked to excess weight.

Study of GS-4571 in healthy people, people with obesity, and people with type 2 diabetes

This trial tests an experimental drug called GS-4571 in three groups: healthy individuals, people with obesity (but not diabetes), and people with type 2 diabetes who are not obese. The study aims to see how the drug affects the body and how safe it is.

Study of eloralintide for people with obesity or overweight

This trial tests if an investigational drug called eloralintide can help people with obesity or overweight lose weight. It is for people who do not have type 2 diabetes and who have tried but struggled to lose weight on their own.

Personalized vs standard care to prevent heart attacks

This trial compares two ways to prevent heart attacks and strokes: one uses a special heart CT scan to guide care, the other uses standard risk factors like blood pressure and cholesterol. You may be eligible if you are older (men over 55, women over 65) and have diabetes, prediabetes, or metabolic syndrome.

Study of eloralintide for type 2 diabetes and weight

This study tests a new medicine called eloralintide for people with type 2 diabetes who are overweight or have obesity. It aims to see if the drug can help with weight loss and blood sugar control.

Safety study of AZD4248 in healthy people and those with kidney disease and diabetes

This trial tests an experimental drug called AZD4248 to see if it's safe for healthy people and for people with chronic kidney disease and type 2 diabetes. It also checks if a home device can accurately measure kidney function.

Home strength training for diabetes and mild memory loss

This study tests whether a home strength-training program using a smartphone app is doable for older adults with type 2 diabetes who also have mild memory problems. You'll do simple exercises at home, and the program may help improve your thinking and glucose control.

Testing ELU42 spray for diabetic foot ulcers

This study tests a new topical spray (ELU42) to help heal diabetic foot ulcers. It may be a good option if you have a non-infected, non-ischemic ulcer and your blood sugar is reasonably controlled.

Real-world data registry for wound care treatments

This study collects information on various wound types and how they respond to standard care. It aims to learn what works best for wounds that haven't healed after 4 weeks of treatment.