Clinical trials · Massachusetts
Type 1 diabetes clinical trials in Massachusetts
We’re tracking 46 recruiting type 1 diabetes studies with a site in Massachusetts — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Massachusetts
- NCT07224321RecruitingPhase 2
Inhaled insulin for youth with newly diagnosed type 1 diabetes
This study tests an inhaled insulin called Afrezza for teenagers and children who have just been diagnosed with type 1 diabetes. It aims to see if this new way of taking insulin can help manage blood sugar and fit into their lives.
Boston, MassachusettsAges 6–17 - NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Boston, MassachusettsAges 12–35 - NCT07197788Enrolling by invitation
Continued access to the Endogenex device study for type 2 diabetes
This trial offers continued access to the Endogenex system for people who were in the sham (placebo) group of the ReCET study and have completed their 12-month visit. It tests a device that treats the duodenum to improve blood sugar control.
Quincy, MassachusettsAges 22 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Braintree, MassachusettsAges 18 years+ - NCT07579702Recruiting
Omnipod 6 Versus Omnipod 5 Insulin Pump System
This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.
Boston, MassachusettsAges 14–75 - NCT04629586Recruiting
T1D Exchange registry for people with type 1 diabetes
This trial registry collects information about people living with type 1 diabetes to help researchers better understand the condition. It may help by allowing future studies and improving how care is studied and planned.
Boston, MassachusettsAges Any age - NCT04786262RecruitingPhase 3
Study of VX-880 for long-standing type 1 diabetes
This Phase 3 trial tests how safe, tolerable, and effective VX-880 is for people with type 1 diabetes who have had it for many years. It may help reduce problems related to blood sugar swings, especially severe low blood sugar episodes.
Boston, MassachusettsAges 18–65 - NCT05734313Recruiting
Teletherapy CBT for anxiety and depression in people with diabetes
This trial tests a unified, talk-therapy program delivered by video (telemedicine) to help with anxiety and depressive symptoms. If you have type 1 diabetes and symptoms of anxiety or depression, it may help you learn coping skills and improve mood.
Boston, MassachusettsAges 18–64 - NCT05899166Recruiting
Diet study to improve blood sugar control in new diabetes
This study looks at how carbohydrate intake may affect how well insulin-producing cells work and how stable your blood sugar becomes in children with newly diagnosed type 1 diabetes. It may help families learn dietary steps that improve glucose control early on.
Boston, MassachusettsAges 5–12 - NCT06141434Recruiting
Maternal Exposures and Baby Diabetes Risk Study
This study follows pregnant women and their babies to learn how early-life factors may affect the risk of type 1 diabetes. If your baby has a parent or sibling with type 1 diabetes, you may be able to join.
Boston, MassachusettsAges birth–99 years - NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Boston, MassachusettsAges 18–75 - NCT06236607Recruiting
Artificial pancreas trial for adults with type 1 diabetes
This trial tests a hybrid closed-loop system that automatically adjusts insulin delivery. It may help you manage your blood sugar more easily if you currently give yourself daily insulin shots.
Boston, MassachusettsAges 18–75 - NCT06860516Recruiting
HLA Demographics Study in Adults With Type 1 Diabetes
This study (NCT06860516) is an observational trial of adults aged 18-55 with type 1 diabetes diagnosed within 6 months. It aims to collect demographic and HLA data.
Boston, MassachusettsAges 18–55 - NCT06919354RecruitingPhase 1
Study of GNTI-122 for new type 1 diabetes
This study tests a new treatment called GNTI-122 for adults recently diagnosed with type 1 diabetes who still make some insulin. It aims to see if the treatment can help protect the cells that produce insulin.
Boston, MassachusettsAges 18–55 - NCT06931275Recruiting
Reducing technology gaps in type 1 diabetes care
This trial tests if sending reminders to doctors can help more Black and Hispanic people with type 1 diabetes get access to helpful diabetes technology. It aims to reduce unfair differences in who gets to use these tools.
Boston, MassachusettsAges 2–95 - NCT06959316Recruiting
T1D Pregnancy & Me
This study tests how well continuous glucose monitors (CGMs) help manage type 1 diabetes during pregnancy. If you are pregnant, have type 1 diabetes, and regularly use a CGM, this trial may help you track your blood sugar and improve your baby's health.
Boston, MassachusettsAges 18 years+ - NCT07011147Recruiting
Real-world test of automated insulin delivery in primary care
This study tests if an automated insulin delivery system (the iLet bionic pancreas) works well in real-world primary care settings for people with type 1 or type 2 diabetes. It aims to see if this technology can help manage blood sugar more easily.
Boston, MassachusettsAges 18–89 - NCT07142252RecruitingPhase 2
New drug for recently diagnosed type 1 diabetes
This trial tests a new medicine (rezpegaldesleukin) to see if it can help preserve the body's ability to make some insulin in people recently diagnosed with type 1 diabetes. It's for children and adults diagnosed within the past 100 days.
Boston, MassachusettsAges 8–45 - NCT07187531RecruitingPhase 2
Testing a new drug to slow type 1 diabetes progression
This trial tests an experimental drug called SAB-142 to see if it can slow down or stop the progression of type 1 diabetes. It is designed for people who were recently diagnosed and still produce some insulin on their own.
Boston, MassachusettsAges 5–40 - NCT02734277Recruiting
Extending a past Type 1 diabetes immune study
This study is for people who already took part in an earlier immune-tolerance program for Type 1 diabetes. It tests whether continuing follow-up and assessments can be done safely and may help learn more about long-term immune effects of treatment.
Boston, MassachusettsAges 8–35 - NCT07676565Recruiting
Adding new drugs to insulin for type 1 diabetes
This study tests whether adding certain diabetes pills (GLP-1 receptor agonists or SGLT inhibitors) to insulin is safe and helpful for adults with type 1 diabetes. Doctors will check your glucose monitor data to see how well this works.
Boston, MassachusettsAges 18 years+ - NCT07076199RecruitingPhase 3
Weekly vs daily insulin for type 1 diabetes
This study tests a new once-weekly insulin (icodec) against a standard daily insulin (glargine), both taken with mealtime insulin. It aims to see which works better to control blood sugar in adults with type 1 diabetes.
Boston, MassachusettsAges 18 years+ - NCT07521475Recruiting
Fully Closed Loop Insulin Pump for Type 2 Diabetes
This study tests a new automated insulin pump system (Omnipod) that adjusts insulin doses on its own throughout the day for people with type 2 diabetes. The goal is to see if it helps keep blood sugar levels more stable while reducing the burden of manual insulin management.
Boston, MassachusettsAges 18–75 - NCT07271043Recruiting
High-protein drink for weight loss in type 2 diabetes
This study tests if a high-protein diabetes shake can help people with type 2 diabetes who are starting a new class of diabetes medications (GLP-1 or GIP receptor agonists) lose weight and improve body composition. Participants will either take the shake or a placebo drink for several weeks.
Boston, MassachusettsAges 18–75
Type 1 diabetes trials by city in Massachusetts
Where these studies are running in Massachusetts
Institutions with a site for the recruiting type 1 diabetes studies listed above.
- Joslin Diabetes Center · 13 studies
- Massachusetts General Hospital · 2 studies
- T1D Exchange · 2 studies
- Boston Children's Hospital
- Boston Medical Center
- Boston University
- Brigham and Women's Hospital
- Care Access
What taking part in a type 1 diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Type 1 diabetes trials in other states
Common questions
- Are there type 1 diabetes clinical trials in Massachusetts?
- Yes. We're currently tracking 46 recruiting type 1 diabetes studies with a site in Massachusetts, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a type 1 diabetes study in Massachusetts?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Massachusetts to take part?
- Not necessarily. These studies have a site in Massachusetts, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a type 1 diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New type 1 diabetes studies open in Massachusetts regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.