Clinical trials · California
Type 1 diabetes clinical trials in California
We’re tracking 83 recruiting type 1 diabetes studies with a site in California — including Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07224321RecruitingPhase 2
Inhaled insulin for youth with newly diagnosed type 1 diabetes
This study tests an inhaled insulin called Afrezza for teenagers and children who have just been diagnosed with type 1 diabetes. It aims to see if this new way of taking insulin can help manage blood sugar and fit into their lives.
Los Angeles, CaliforniaAges 6–17 - NCT07228117Recruiting
Testing a new automated insulin pump for people with diabetes
This study tests a new automated insulin delivery system (a pump that helps manage blood sugar) in children and adults with diabetes. It aims to see if the system is safe and easy to use in daily life.
Escondido, CaliforniaAges 7–85 - NCT06329375Recruiting
Food Help for Diabetes Patients After Hospital Stay
This study helps people with diabetes who are admitted to Stanford Hospital and have trouble affording enough food. It provides meals through Mom's Meals after you go home, to make sure you have healthy food options.
Palo Alto, CaliforniaAges 18 years+ - NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
Huntington Beach, CaliforniaAges 1–25 - NCT06783309RecruitingPhase 1/Phase 2
Testing CNP-103 for newly diagnosed type 1 diabetes
This trial tests a new study drug called CNP-103 for people ages 12-35 who were recently diagnosed (within 6 months) with stage 3 type 1 diabetes. The goal is to see if the drug can help preserve the body's ability to make some insulin, potentially slowing the need for more insulin shots.
Newport Beach, CaliforniaAges 12–35 - NCT06408207Recruiting
CGM Academy for Youth with Type 1 Diabetes
This study tests a program to help young people with type 1 diabetes learn to use continuous glucose monitors (CGMs) like Dexcom G6 and G7. It aims to improve diabetes management through education and support.
Los Angeles, CaliforniaAges 8–18 - NCT05762107RecruitingPhase 2
Drug ZT-01 to reduce low blood sugar at night
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
San Carlos, CaliforniaAges 18–75 - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Concord, CaliforniaAges 18 years+ - NCT07579702Recruiting
Omnipod 6 Versus Omnipod 5 Insulin Pump System
This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.
Los Angeles, CaliforniaAges 14–75 - NCT06836479Recruiting
Testing cultural meals for Asian Americans with type 2 diabetes
This study tests whether specially prepared meals that match your cultural background can help manage blood sugar levels. You'll wear a small sensor to track your glucose for 30 days and eat tailored meals for one week.
Stanford, CaliforniaAges 18 years+ - NCT07675161Recruiting
MiniMed wearable device study for children with diabetes
This study tests a small wearable device that helps manage diabetes. It is designed for children and teens ages 7 to 17 who use insulin, and aims to see how well the device fits and works in daily life.
Sacramento, CaliforniaAges 7–17 - NCT03746769RecruitingPhase 1/Phase 2
Testing gastrin to improve results of islet cell transplant
This trial looks at whether adding gastrin can improve outcomes after an islet cell transplant for people with type 1 diabetes. It may help some participants achieve better blood sugar control, but it also requires close follow-up and immune-suppressing medications to protect the new cells.
Duarte, CaliforniaAges 18–68 - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Covina, CaliforniaAges 18 years+ - NCT04428658Recruiting
Telehealth coaching for kids to improve blood sugar control
This trial tests whether extra diabetes coaching delivered through online video and online messages can lower blood sugar levels in children with type 1 diabetes. It may help your child improve diabetes control by combining real-time and non-real-time support.
Sacramento, CaliforniaAges 5–18 - NCT04786262RecruitingPhase 3
Study of VX-880 for long-standing type 1 diabetes
This Phase 3 trial tests how safe, tolerable, and effective VX-880 is for people with type 1 diabetes who have had it for many years. It may help reduce problems related to blood sugar swings, especially severe low blood sugar episodes.
San Francisco, CaliforniaAges 18–65 - NCT04933851RecruitingPhase 2
Support for emotional distress in adults with type 1 diabetes
This study tests an emotional support program to help people with type 1 diabetes who feel significant diabetes-related distress. It may improve how you cope and support better diabetes outcomes.
San Diego, CaliforniaAges 18 years+ - NCT05505669Recruiting
Blood test study to track markers in diabetes
This study measures “circulating biomarkers” (blood-based signals) in people with type 1 or type 2 diabetes, and in some people without diabetes who test positive for certain diabetes antibodies. The goal is to understand what these blood signals can tell us about diabetes development and progression.
Duarte, CaliforniaAges Any age - NCT06217302RecruitingPhase 3
Sotagliflozin for kidney protection in type 1 diabetes
This study tests whether sotagliflozin (a pill that helps control blood sugar and protects the kidneys) can slow down kidney function decline in people with type 1 diabetes and diabetic kidney disease. You may qualify if you have had type 1 diabetes for at least 8 years, have moderate kidney damage, and are on standard treatments.
Stanford, CaliforniaAges 18–75 - NCT06453928Recruiting
Starting technology for high-risk type 1 diabetes
This study tests a new approach to help people with type 1 diabetes who have high blood sugar (A1c above 8.5%) and are not on an insulin pump. It looks at whether using diabetes technology can improve your glucose control.
Santa Monica, CaliforniaAges 18 years+ - NCT06481904Recruiting
Registry for stage 2 type 1 diabetes
This study tracks people with stage 2 type 1 diabetes to see how they do over time, either with or without treatment with a drug called TZIELD. It helps doctors learn more about the disease and the effects of this treatment.
Los Angeles, CaliforniaAges Any age - NCT06524960RecruitingPhase 1/Phase 2
Denosumab for Preserving Insulin in Type 1 Diabetes
This study tests if denosumab, a drug normally used for bone health, can help preserve your body's own insulin production in type 1 diabetes. It might slow the loss of insulin-making cells, helping you maintain better blood sugar control over time.
Duarte, CaliforniaAges 18–50 - NCT06657209RecruitingPhase 4
Comparing diabetes treatments for people with normal weight
This study tests two medications—pioglitazone (a pill) and tirzepatide (an injection)—in people with type 2 diabetes who have a normal body weight. It aims to find which treatment works better for this specific group.
Stanford, CaliforniaAges 30–70 - NCT07606066Recruiting
Finding Type 2 Diabetes Patients for Future Research Studies
This is a screening study to identify and understand people with type 2 diabetes whose blood sugar isn't well controlled, so they can potentially join future diabetes research trials. You won't receive a new treatment in this study—it's about getting to know your health history and seeing if you might be a good fit for upcoming studies.
Lincoln, CaliforniaAges 18 years+ - NCT06860516Recruiting
HLA Demographics Study in Adults With Type 1 Diabetes
This study (NCT06860516) is an observational trial of adults aged 18-55 with type 1 diabetes diagnosed within 6 months. It aims to collect demographic and HLA data.
San Francisco, CaliforniaAges 18–55
Type 1 diabetes trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting type 1 diabetes studies listed above.
- University of California, San Francisco · 6 studies
- City of Hope Comprehensive Cancer Center · 4 studies
- Stanford University · 4 studies
- Research Site · 3 studies
- Sansum Diabetes Research Institute · 3 studies
- Children's Hospital Los Angeles · 2 studies
- Headlands Research - AMCR Institute · 2 studies
- Rady Children's Hospital San Diego · 2 studies
What taking part in a type 1 diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Type 1 diabetes trials in other states
Common questions
- Are there type 1 diabetes clinical trials in California?
- Yes. We're currently tracking 83 recruiting type 1 diabetes studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a type 1 diabetes study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a type 1 diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New type 1 diabetes studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.