Clinical trials · California
Type 1 diabetes clinical trials in California
We’re tracking 89 recruiting type 1 diabetes studies with a site in California — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07061574RecruitingPhase 1/Phase 2
Immune treatment for new onset type 1 diabetes
This study tests a low dose of a drug that calms the immune system, followed by either another immune drug or a blood pressure medicine, to see if they can help preserve the body's ability to make insulin in people recently diagnosed with type 1 diabetes. It may help keep your own insulin production going longer.
Los Angeles, CaliforniaAges 9–20 - NCT07676565Recruiting
Adding new drugs to insulin for type 1 diabetes
This study tests whether adding certain diabetes pills (GLP-1 receptor agonists or SGLT inhibitors) to insulin is safe and helpful for adults with type 1 diabetes. Doctors will check your glucose monitor data to see how well this works.
Newport Beach, CaliforniaAges 18 years+ - NCT03746769RecruitingPhase 1/Phase 2
Testing gastrin to improve results of islet cell transplant
This trial looks at whether adding gastrin can improve outcomes after an islet cell transplant for people with type 1 diabetes. It may help some participants achieve better blood sugar control, but it also requires close follow-up and immune-suppressing medications to protect the new cells.
Duarte, CaliforniaAges 18–68 - NCT07864168Recruiting
Long-lasting glucose sensor study for type 1 and type 2 diabetes
This study tests a new extended-wear sensor that helps track glucose levels continuously. It is designed to see if a next-generation sensor is accurate and safe for people with diabetes.
Chula Vista, CaliforniaAges 2–80 - NCT07797335RecruitingPhase 3
Zenagamtide for diabetes and weight loss
This study compares a new once-weekly injection to lower blood sugar levels against a standard daily injection in people with type 2 diabetes who are at high risk for heart problems. It aims to find out if the new medicine is more effective in managing blood sugar and body weight.
Lancaster, CaliforniaAges 45 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Sacramento, CaliforniaAges 18 years+ - NCT07662213RecruitingPhase 3
Elecoglipron vs semaglutide for type 2 diabetes
This study tests an experimental diabetes pill (elecoglipron) to see if it works as well as a current medicine, semaglutide, for people with type 2 diabetes who also have heart risk factors. It aims to help better control blood sugar and weight.
Sacramento, CaliforniaAges 18 years+ - NCT07606066Recruiting
Finding Type 2 Diabetes Patients for Future Research Studies
This is a screening study to identify and understand people with type 2 diabetes whose blood sugar isn't well controlled, so they can potentially join future diabetes research trials. You won't receive a new treatment in this study—it's about getting to know your health history and seeing if you might be a good fit for upcoming studies.
Lincoln, CaliforniaAges 18 years+ - NCT07579702Recruiting
Omnipod 6 Versus Omnipod 5 Insulin Pump System
This study compares two versions of the Omnipod insulin pump system to see if the newer Omnipod 6 works better at managing blood sugar than the current Omnipod 5. You'll wear one of these systems for several months and share data about how well it helps control your diabetes.
Los Angeles, CaliforniaAges 14–75 - NCT07518004Recruiting
ROME GS System Study for diabetes glucose monitoring
This study tests the ROME GS System, a glucose monitoring device that measures blood sugar levels. The system includes a sensor placed under the skin and a transmitter worn on the body. If you have diabetes and want to help evaluate a new way to track your blood sugar, this trial may be for you.
Escondido, CaliforniaAges 18 years+ - NCT07386340Recruiting
Testing a new continuous glucose monitor with flash readings
This study tests a new sensor system that tracks glucose levels continuously and can give a quick reading when you wave a device over it. It aims to see if it's safe and accurate for people with diabetes.
Escondido, CaliforniaAges 18 years+ - NCT07260110Recruiting
Study of teplizumab vs. no treatment in stage 2 type 1 diabetes
This study watches people with stage 2 type 1 diabetes who either get teplizumab or not, to compare their real-world experiences. It helps researchers learn how the drug affects daily life.
San Francisco, CaliforniaAges 8 years+ - NCT04428658Recruiting
Telehealth coaching for kids to improve blood sugar control
This trial tests whether extra diabetes coaching delivered through online video and online messages can lower blood sugar levels in children with type 1 diabetes. It may help your child improve diabetes control by combining real-time and non-real-time support.
Sacramento, CaliforniaAges 5–18 - NCT07224321RecruitingPhase 2
Inhaled insulin for youth with newly diagnosed type 1 diabetes
This study tests an inhaled insulin called Afrezza for teenagers and children who have just been diagnosed with type 1 diabetes. It aims to see if this new way of taking insulin can help manage blood sugar and fit into their lives.
Los Angeles, CaliforniaAges 6–17 - NCT07222137RecruitingPhase 3
Baricitinib to delay type 1 diabetes in at-risk people
This trial tests if baricitinib, a pill that calms the immune system, can slow down or delay the onset of type 1 diabetes in children and adults who are at high risk. It is for people whose blood sugar is already starting to rise but who do not yet need insulin.
Santa Barbara, CaliforniaAges 1–35 - NCT07187531RecruitingPhase 2
Testing a new drug to preserve insulin production in type 1 diabetes
This study tests a new drug called SAB-142, which aims to stop the immune system from attacking insulin-making cells in type 1 diabetes. It may help preserve your body's ability to make insulin. The trial will check if the drug is safe and effective.
San Francisco, CaliforniaAges 5–40 - NCT07142252RecruitingPhase 2
New drug for recently diagnosed type 1 diabetes
This trial tests a new medicine (rezpegaldesleukin) to see if it can help preserve the body's ability to make some insulin in people recently diagnosed with type 1 diabetes. It's for children and adults diagnosed within the past 100 days.
San Francisco, CaliforniaAges 8–45 - NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
San Diego, CaliforniaAges 1–25 - NCT06981234RecruitingPhase 2
Acetazolamide for type 1 diabetes
This trial tests whether a medicine called acetazolamide (used for altitude sickness) can help people with type 1 diabetes. It compares how your body responds while on the drug versus a placebo, using a crossover design so everyone gets both treatments.
La Jolla, CaliforniaAges 18 years+ - NCT06964087RecruitingPhase 2
Testing OPT101 for type 1 diabetes
This trial tests an investigational drug called OPT101 in people with type 1 diabetes. It aims to see how the drug works in the body and whether it can help preserve insulin production, especially in those diagnosed recently or within the last 20 years.
Walnut Creek, CaliforniaAges 18–50 - NCT06919354RecruitingPhase 1
Study of GNTI-122 for new type 1 diabetes
This study tests a new treatment called GNTI-122 for adults recently diagnosed with type 1 diabetes who still make some insulin. It aims to see if the treatment can help protect the cells that produce insulin.
San Diego, CaliforniaAges 18–55 - NCT06906653Enrolling by invitation
Proactive care for newly diagnosed type 2 diabetes
This trial tests a new, proactive approach to help people newly diagnosed with type 2 diabetes manage their condition through better initial care and support. If you’re a Kaiser Permanente Northern California member, you may get extra resources and guidance right from the start.
Pleasanton, CaliforniaAges 18–74 - NCT06860516Recruiting
HLA Demographics Study in Adults With Type 1 Diabetes
This study (NCT06860516) is an observational trial of adults aged 18-55 with type 1 diabetes diagnosed within 6 months. It aims to collect demographic and HLA data.
San Francisco, CaliforniaAges 18–55 - NCT06836479Recruiting
Testing cultural meals for Asian Americans with type 2 diabetes
This study tests whether specially prepared meals that match your cultural background can help manage blood sugar levels. You'll wear a small sensor to track your glucose for 30 days and eat tailored meals for one week.
Stanford, CaliforniaAges 18 years+
Type 1 diabetes trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting type 1 diabetes studies listed above.
- University of California, San Francisco · 7 studies
- Research Site · 3 studies
- Ridley-Tree Cancer Center · 3 studies
- City of Hope · 2 studies
- Headlands Research - AMCR Institute · 2 studies
- Stanford University · 2 studies
- Children's Hospital Los Angeles
- Diablo Clinical Research
What taking part in a type 1 diabetes study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Type 1 diabetes trials in other states
Common questions
- Are there type 1 diabetes clinical trials in California?
- Yes. We're currently tracking 89 recruiting type 1 diabetes studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a type 1 diabetes study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a type 1 diabetes trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New type 1 diabetes studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.