Clinical trials
Type 1 diabetes clinical trials
An autoimmune condition where the body makes little or no insulin. We’re tracking 862 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07041268RecruitingPhase 2
Rituximab for recent type 1 diabetes in teens
This trial tests if repeated infusions of rituximab (a drug that calms the immune system) can help preserve insulin production in adolescents newly diagnosed with type 1 diabetes. It is for teens in Russia who started diabetes treatment within the last 4 months.
MoscowAges 12–18 - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT06994403Recruiting
Pasta and blood sugar in type 1 diabetes
This study checks how eating a special carb-enriched pasta affects blood sugar in people with type 1 diabetes and compares it to healthy volunteers. It may help find better mealtime strategies for managing diabetes.
NaplesAges 18–50 - NCT07021456Recruiting
How diet education affects eating disorder risk in type 1 diabetes
This study looks at how learning about counting carbs and adjusting insulin (called Functional Insulin Therapy) might impact eating habits and the risk of eating disorders in adults with type 1 diabetes.
GrenobleAges 18 years+ - NCT07006272Recruiting
Closed-loop pump vs islet transplant for unstable type 1 diabetes
This study compares two advanced treatments for type 1 diabetes that is hard to control: a closed-loop insulin pump system (which automatically adjusts insulin) versus islet cell transplantation (which replaces the cells that make insulin). It is for people whose blood sugar stays very unstable despite using the best current therapies.
Lyon, Auvergne-Rhône-AlpesAges 18 years+ - NCT07011147Recruiting
Real-world test of automated insulin delivery in primary care
This study tests if an automated insulin delivery system (the iLet bionic pancreas) works well in real-world primary care settings for people with type 1 or type 2 diabetes. It aims to see if this technology can help manage blood sugar more easily.
Aurora, ColoradoAges 18–89 - NCT07005986Recruiting
Pyrophosphate as a biomarker for artery hardening in type 2 diabetes
This study looks at a substance in the blood called pyrophosphate that may help doctors detect a type of artery hardening (mediacalcinosis) in people with type 2 diabetes. It tests whether this substance can be a useful early warning sign.
Nice, FranceAges 40–70 - NCT05159856Recruiting
Early checks for long-term complications in young type 1 diabetes
This study looks for early signs of long-term complications in children and teens who have type 1 diabetes for more than a year. It may help your clinic spot problems sooner, when treatment could be easier.
Herlev, HerlevAges 6–18 - NCT06984185Recruiting
Early detection of type 1 diabetes in children
This trial is looking for children with newly diagnosed type 1 diabetes to study how to detect the condition earlier. It focuses on kids who have already reached the stage where symptoms appear, to improve understanding of the disease.
Bron, RhôneAges 1–18 - NCT06981234RecruitingPhase 2
Acetazolamide for type 1 diabetes
This trial tests whether a medicine called acetazolamide (used for altitude sickness) can help people with type 1 diabetes. It compares how your body responds while on the drug versus a placebo, using a crossover design so everyone gets both treatments.
La Jolla, CaliforniaAges 18 years+ - NCT06976619RecruitingPhase 2
Blood sugar control and a diabetes drug on insulin production
This study looks at how blood sugar control and a class of drugs called GLP-1 agonists (like Ozempic) affect insulin-making cells in people with type 1 or type 2 diabetes who use insulin.
Rochester, MinnesotaAges 25–70 - NCT06964087RecruitingPhase 2
Testing OPT101 for type 1 diabetes
This trial tests an investigational drug called OPT101 in people with type 1 diabetes. It aims to see how the drug works in the body and whether it can help preserve insulin production, especially in those diagnosed recently or within the last 20 years.
Birmingham, AlabamaAges 18–50 - NCT06967701Recruiting
Building exercise habits for type 1 diabetes
This study helps adults with type 1 diabetes who don't exercise much build a safe and lasting exercise routine. You'll learn how to start moving more while managing your insulin and blood sugar levels.
New Haven, ConnecticutAges 30–65 - NCT06810726RecruitingPhase 2
Platelet-rich fibrin gel for diabetic foot ulcers
This trial tests a special gel made from your own blood (platelet-rich fibrin, or PRF) to help heal diabetic foot ulcers that are not getting better with standard care. It may be an option if you have a mild-to-moderate ulcer on the bottom of your foot with good blood flow and no infection.
Corpus Christi, TexasAges 18–80 - NCT05065372RecruitingPhase 1
Metformin test with automated insulin in teens with type 1
This Phase 1 study tests how adding metformin affects blood flow in the kidneys, insulin sensitivity, and overall heart/metabolic health in young people with type 1 diabetes. It may help researchers understand whether this combo is safe and beneficial alongside automated or pump/shot insulin care.
Aurora, ColoradoAges 12–25 - NCT06945406RecruitingPhase 1
Study of an investigational drug for diabetes
This trial tests a new medicine, LY4057996, in people with type 1 or type 2 diabetes and in healthy volunteers. It aims to see if the drug is safe and how it works in the body.
NeussAges 18 years+ - NCT06936280Recruiting
Type 1 diabetes and diabetes distress study
This trial tests a program for young adults with type 1 diabetes who feel stressed or overwhelmed by their diabetes. The goal is to see if the program can help reduce diabetes distress and improve well-being.
EsbjergAges 18–35 - NCT06738849Recruiting
Testing an app for insulin dosing
This trial tests the EkiYou smartphone app to help calculate your mealtime insulin dose. You need to have diabetes, use both a long-acting and a short-acting insulin pen, and be comfortable with a CGM and a smartphone.
BobignyAges 18 years+ - NCT06919354RecruitingPhase 1
Study of GNTI-122 for new type 1 diabetes
This study tests a new treatment called GNTI-122 for adults recently diagnosed with type 1 diabetes who still make some insulin. It aims to see if the treatment can help protect the cells that produce insulin.
Duarte, CaliforniaAges 18–55 - NCT06915831Recruiting
Type 1 diabetes and sleep apnea study
This study looks at how sleep apnea affects blood sugar control in adults with type 1 diabetes. It may help researchers understand if treating sleep apnea improves diabetes management.
Chicago, IllinoisAges 18–50 - NCT06904846Enrolling by invitation
Testing a new continuous glucose monitor for 60 days
This study tests a new continuous glucose monitor (CGM) called iCan o3 that you wear on your abdomen for 60 days. It helps track your blood sugar levels continuously, so you and your doctor can see patterns and make better decisions about your diabetes care.
AntwerpAges 18–75 - NCT06876207Recruiting
Real-world study of Control-IQ in teens with type 1 diabetes who exercise regularly
This study observes how well the Control-IQ insulin pump system works for teenagers with type 1 diabetes who exercise at least twice a week. It aims to see if the technology is safe and effective during regular physical activity.
Messina, ItalyAges Up to 20 years - NCT06906653Enrolling by invitation
Proactive care for newly diagnosed type 2 diabetes
This trial tests a new, proactive approach to help people newly diagnosed with type 2 diabetes manage their condition through better initial care and support. If you’re a Kaiser Permanente Northern California member, you may get extra resources and guidance right from the start.
Pleasanton, CaliforniaAges 18–74 - NCT06897904Recruiting
Blood and clotting tests in type 1 diabetes kids
This study looks at blood cell counts and clotting function in children with type 1 diabetes. It aims to find any changes that might be related to diabetes, which could help with better monitoring and care.
Asyut, Asyut GovernorateAges Up to 18 years
Hear when a new Type 1 diabetes trial opens
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Common questions
- Are there clinical trials for type 1 diabetes?
- Yes. Clin2 currently lists 862 recruiting type 1 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 1 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 1 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.