Clinical trials
Type 2 diabetes clinical trials
A condition where the body can’t use insulin properly, raising blood sugar. We’re tracking 1,079 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05469659RecruitingPhase 2
Test drug to slow kidney damage in type 2 diabetes
This Phase 2 study compares tofogliflozin to metformin to see how well they reduce urine albumin levels (a marker of kidney stress) in people with diabetic kidney disease. You might benefit if your type 2 diabetes is affecting your kidneys despite standard blood-pressure medicines.
Matsumoto, NaganoAges 20 years+ - NCT06567795Recruiting
Monitoring heart risk with a wearable sensor in diabetes
This trial tests a wearable chest sensor (called HEMOTAG) to monitor heart events in people with long-standing Type 2 diabetes who also have heart disease or specific diabetes-related complications. The sensor is worn at home for short periods to catch early signs of heart trouble, aiming to improve personalized care.
West Palm Beach, FloridaAges 40 years+ - NCT06957093Recruiting
AI‐assisted diabetes care vs standard management
This study tests whether an AI‐powered digital health platform can help people with type 2 diabetes better manage their blood sugar. If you use a smartphone and have had diabetes for at least a year, this may be a convenient way to receive extra support.
Changchun, JilinAges 18–75 - NCT06979440Recruiting
Berberine for diabetes with depression
This trial tests if berberine, a natural compound, can improve both blood sugar and mood in people who have type 2 diabetes and major depression. It aims to understand how berberine works at a molecular level.
Nantong, JiangsuAges 18–65 - NCT07165223RecruitingPhase 3
Testing a new insulin for type 2 diabetes
This trial tests a new weekly insulin called GZR4 for people with type 2 diabetes who already use basal insulin. It aims to see how well it controls blood sugar and if it is safe.
Linyi, ShandongAges 18 years+ - NCT07270068Recruiting
Diabetes remission through lifestyle change for Malaysian patients
This study tests whether a lifestyle program can help Malaysian adults with recently diagnosed type 2 diabetes and overweight or obesity achieve remission of their diabetes. If you qualify, you’ll get support to change your diet and activity habits.
Seremban, Negeri SembilamAges 18–70 - NCT07282743RecruitingPhase 2
Study of GL0034 for overweight or obese adults with type 2 diabetes
This trial tests a new medication, GL0034, to see if it helps with weight loss and blood sugar control in people with type 2 diabetes who are overweight. Participants must already be taking metformin and not using other diabetes drugs.
Little Rock, ArkansasAges 18 years+ - NCT02817360RecruitingPhase 4
Preventing heart events in people with type 2 diabetes
This trial tests a heart-focused prevention approach to lower the risk of cardiac (heart) events in adults with type 2 diabetes. It may help by targeting early stress on the heart measured with a specific blood test.
Mödling, Lower AustriaAges 18 years+ - NCT07549373Recruiting
Laser and natural treatments for tooth root infections in diabetics
This study tests whether diode laser (a type of focused light), gudmar (an herbal supplement), and vinegar can help treat tooth infections during root canal therapy in people with type 2 diabetes. The goal is to see if these treatments reduce infection and improve healing.
Noida, Uttar PradeshAges 25–60 - NCT05762107RecruitingTeam says not enrollingPhase 2
Drug ZT-01 to reduce low blood sugar at night
This Phase 2 study tests ZT-01 to help prevent night-time low blood sugar (hypoglycemia) in people with type 1 diabetes. It may help if you’ve had low blood sugar during sleep or are at high risk based on recent glucose monitoring.
Birmingham, AlabamaAges 18–75 - NCT07187531RecruitingPhase 2
Testing a new drug to preserve insulin production in type 1 diabetes
This study tests a new drug called SAB-142, which aims to stop the immune system from attacking insulin-making cells in type 1 diabetes. It may help preserve your body's ability to make insulin. The trial will check if the drug is safe and effective.
San Francisco, CaliforniaAges 5–40 - NCT07061574RecruitingPhase 1/Phase 2
Study of immune-modulating drugs for new-onset type 1 diabetes
This study tests two different medications (Anti-Thymocyte Globulin and Adalimumab or Verapamil) to see if they can slow down the loss of insulin production in people with newly diagnosed type 1 diabetes. Participants will be randomly assigned to receive one of the treatments and will be followed for about a year to see how well their bodies still make insulin.
San Francisco, CaliforniaAges 9–20 - NCT07224321RecruitingPhase 2
Inhaled insulin for youth with newly diagnosed type 1 diabetes
This study tests an inhaled insulin called Afrezza for teenagers and children who have just been diagnosed with type 1 diabetes. It aims to see if this new way of taking insulin can help manage blood sugar and fit into their lives.
Los Angeles, CaliforniaAges 6–17 - NCT05478707RecruitingPhase 2
Treating small blood vessel problems in type 1 diabetes
This study tests whether two different treatment strategies can improve the function of the tiny blood vessels in people with type 1 diabetes. It aims to find a way to prevent or reduce diabetes-related complications.
Orlando, FloridaAges 18–40 - NCT07088068RecruitingPhase 3
Teplizumab for newly diagnosed type 1 diabetes
This study tests whether teplizumab can help keep the body making insulin in people recently diagnosed with type 1 diabetes. It is for children and young adults aged 1 to 25, and compares the drug against a placebo.
Scottsdale, ArizonaAges 1–25 - NCT06820281RecruitingPhase 2
Tirzepatide for type 1 diabetes: a metabolism study
This study tests if tirzepatide, a medicine that helps lower blood sugar and manage weight, is safe and effective for people with type 1 diabetes who are overweight or have obesity. You must already use an automated insulin pump system.
Sydney, New South WalesAges 18–65 - NCT06752369Recruiting
Online program for teens with type 1 diabetes and depression
This study tests a short online program to help teens with type 1 diabetes who feel down. It aims to see if a few sessions can improve mood and diabetes management.
Orlando, FloridaAges 12–17 - NCT07548996RecruitingPhase 2/Phase 3
Study of oral dimethyl fumarate for type 1 diabetes
This study tests an oral capsule called dimethyl fumarate to see if it can help preserve the body’s own insulin production in adults with type 1 diabetes. It may offer a way to slow the loss of beta cells and reduce reliance on insulin.
Nanjing, JiangsuAges 18–65 - NCT07149142Recruiting
AI eye screening for children with type 1 diabetes
This study tests if an artificial intelligence (AI) system can effectively screen for eye problems related to diabetes (retinopathy) in children. The goal is to find a faster, easier way to protect your child's vision.
Prague, Prague 5Ages 11–19 - NCT06784375Recruiting
Personalized diabetes education with a continuous glucose monitor
This study tests if a personalized education program, supported by continuous glucose monitor (CGM) wear, can help adults with type 2 diabetes improve their blood sugar control. Participants will receive extra training and a CGM device to see how food, activity, and medications affect their glucose levels in real time.
Minneapolis, MinnesotaAges 18 years+ - NCT07667504Recruiting
Dietary approaches for weight management in type 1 diabetes
This study tests two different diet approaches to help people with type 1 diabetes who are overweight or obese manage their weight. It aims to find out which eating plan works better for blood sugar control and weight loss.
Málaga, MálagaAges 18–65 - NCT03746769RecruitingPhase 1/Phase 2
Testing gastrin to improve results of islet cell transplant
This trial looks at whether adding gastrin can improve outcomes after an islet cell transplant for people with type 1 diabetes. It may help some participants achieve better blood sugar control, but it also requires close follow-up and immune-suppressing medications to protect the new cells.
Duarte, CaliforniaAges 18–68 - NCT04428658Recruiting
Telehealth coaching for kids to improve blood sugar control
This trial tests whether extra diabetes coaching delivered through online video and online messages can lower blood sugar levels in children with type 1 diabetes. It may help your child improve diabetes control by combining real-time and non-real-time support.
Sacramento, CaliforniaAges 5–18 - NCT04657783Recruiting
French cohort study of people with type 1 diabetes
This study follows people with type 1 diabetes in France to better understand the condition over time. It may help researchers improve future care, especially for how type 1 diabetes starts and is managed from early diagnosis onward.
ParisAges 6–100
Hear when a new Type 2 diabetes trial opens
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Common questions
- Are there clinical trials for type 2 diabetes?
- Yes. Clin2 currently lists 1,079 recruiting type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.