Clinical trials
Type 2 diabetes clinical trials
A condition where the body can’t use insulin properly, raising blood sugar. We’re tracking 1,079 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05785780Enrolling by invitation
Help improve colon cancer screening for people with diabetes
This study looks for better ways to make sure people with diabetes get up-to-date colon cancer screening. If you haven’t had the recommended test on time, it may help identify barriers in primary care and improve screening follow-through.
New Brunswick, New JerseyAges 50–74 - NCT06387199RecruitingPhase 2/Phase 3
Weekly semaglutide with closed-loop system for type 1 diabetes
This trial tests whether adding a weekly semaglutide injection (a GLP-1 drug) to a closed-loop insulin system can help reduce the need for carb counting in people with type 1 diabetes. It aims to improve blood sugar control and make diabetes management easier.
Montreal, QuebecAges Any age - NCT03369821Recruiting
Study of immune changes in very early childhood type 1 diabetes
This study looks at immune system cells and gene activity in infants and young children to understand what causes type 1 diabetes to start so early. It may help researchers find earlier warning signs and better ways to support families right at diagnosis.
Seattle, WashingtonAges Up to 70 years - NCT02969798Recruiting
Study of prediabetes with abnormal sugars and medicines
This study looks at adults with prediabetes—specifically abnormal fasting and/or 2-hour blood sugar tests—to see whether a treatment helps improve sugar control. You may also be compared with people who have normal blood sugar (the control group).
San Antonio, TexasAges 18–65 - NCT06816303Recruiting
Diabetes Treatment in Liver Transplant Patients and Candidates
This study looks at people with type 2 diabetes who are either waiting for a liver transplant or have already had one. Researchers want to understand how diabetes treatment affects outcomes before and after transplant.
Bologna, BOAges 18 years+ - NCT07043426Recruiting
Diabetes care support for social needs
This study tests if connecting people with type 2 diabetes who have high A1C levels (9% or more) to community resources for social needs (like food or housing) can help improve their diabetes control. It aims to see if addressing life challenges outside the clinic helps lower blood sugar.
Boston, MassachusettsAges 18 years+ - NCT06427421Recruiting
Immune cells in children with recent type 1 diabetes
This study looks at immune cells in children who were recently diagnosed with type 1 diabetes. It involves one extra blood draw to better understand how the immune system attacks the pancreas. If you join, no new treatments are given—just observation and analysis of your child's immune cells.
ParisAges 6–18 - NCT04284943Recruiting
Surgery for stomach cancer and diabetes
This trial tests a surgery for early-stage stomach cancer that also aims to improve type 2 diabetes by changing how your body processes food. It might be an option if you have both conditions and are not using insulin.
SeoulAges 20–69 - NCT05681468Recruiting
Ketogenic diet trial for blood sugar and inflammation outcomes
This study compares two versions of a ketogenic (very low-carb) diet to see how they affect blood sugar control and inflammation. It may help people with overweight or obesity who have pre-diabetes-level blood sugar understand which fat sources work better.
Edmonton, AlbertaAges 18–70 - NCT03323216Recruiting
Testing heart-related blood markers in people with diabetes and heart failure
This study looks for blood markers that may help explain or predict heart problems in people who have type 2 diabetes and heart failure. To join, you may also need to be having a planned heart procedure where doctors can collect study information.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT03568630Recruiting
Blood tests to study early pancreatic cancer risk
This study looks at blood “markers” to find early signs or higher risk for pancreatic cancer. You may join if you have certain risk factors (like new diabetes, pancreatic cysts/pancreatitis, or a strong family history) and can come to Omaha for blood draws twice a year.
Omaha, NebraskaAges 19 years+ - NCT03878706Recruiting
Testing diabetes medicines on heart risk and heart failure
This trial studies how diabetes medicines (GLP-1 and SGLT2, alone or together) affect the heart in people with type 2 diabetes who are at higher cardiovascular risk and have heart failure with preserved pumping function. It may help find safer or more effective ways to reduce heart problems.
Athens, AtticaAges 45–80 - NCT05117424Recruiting
Study of metabolism and plaque changes in heart disease
This trial looks at how treating or managing conditions like diabetes, prediabetes, obesity, kidney disease, or high cholesterol affects artery plaque over time. It may help researchers find ways to slow plaque buildup and related heart risks.
ShanghaiAges 18–80 - NCT05156736Recruiting
Study of early heart artery disease in South Asians
This study looks at early buildup of plaque in heart arteries in young adults from Pakistan. It may help doctors understand why this happens earlier and guide better prevention and screening.
Karachi, SindhAges 35–65 - NCT05165706Recruiting
Study of how obesity affects insulin resistance over time
This study follows adults over time to understand how weight and body chemistry relate to insulin resistance. It may help researchers learn why insulin resistance happens and what could prevent or improve it.
Stanford, CaliforniaAges 35–65 - NCT05211375RecruitingPhase 3
Compare two weight-loss surgeries for type 2 diabetes control
This Phase 3 trial compares sleeve gastrectomy versus a different bypass-style operation to improve blood sugar in adults with type 2 diabetes. It may help some people lower blood sugar and diabetes medication needs, but you must meet specific safety and health criteria.
Seongnam-siAges 18 years+ - NCT05275608Recruiting
Low-carb diet effects in people with metabolic syndrome
This trial studies whether a very low-calorie, low-carb diet (VLCKD) can improve metabolic health in adults with metabolic syndrome, fatty liver, and type 2 diabetes. It may help lower blood sugar and improve related health markers if you fit their specific diabetes and liver/kidney criteria.
Novara, ItalyAges 25–65 - NCT05370014Recruiting
Study for COVID survivors and their unpaid carepartners in South Carolina
This study looks at how to improve health and support for African American adults who had COVID-19 severe enough to need urgent care or hospitalization, along with the unpaid carepartner who helps them at home. It may be helpful if you and your carepartner live in a medically underserved or rural area and share daily support needs.
Columbia, South CarolinaAges 18 years+ - NCT05404061Recruiting
Study for people who don’t lose weight after bariatric surgery
This study looks at people who have had bariatric surgery but still struggle to lose weight (or lose it poorly). It aims to better understand how to help “poor responders” and what might be interfering with weight-loss results.
LondonAges 18–70 - NCT05589155Recruiting
Using a phone app to improve blood sugar and weight
This study looks at whether a mobile phone app can help people with type 2 diabetes improve their health habits, including blood sugar monitoring and weight. You may be able to join if you already check your blood sugar daily and are able to use a smartphone.
San Diego, CaliforniaAges 18–64 - NCT05934409Recruiting
Measuring body-fat storage after bariatric surgery
This study looks at how body fat is stored and how that may relate to early improvements in diabetes and heart/liver health after bariatric surgery. It may help researchers understand why some people recover faster and which body changes matter.
Sherbrooke, QuebecAges 18–65 - NCT05962372Recruiting
Culturally tailored diet program for adults in Puerto Rico
This study tests a diet program designed to fit Puerto Rico culture and daily life. It may help adults with weight or blood sugar or blood fat concerns improve their health through regular check-ins.
San JuanAges 30–65 - NCT06003634Recruiting
Peer Support for Type 2 Diabetes in Rural Kentucky
This study tests whether having a trained peer coach (a person who also has diabetes) can help older adults in rural Kentucky better manage their Type 2 Diabetes. If you join, you'll get support from someone who understands your experience.
Bowling Green, KentuckyAges 55 years+ - NCT06098417Recruiting
Fatty liver markers before weight-loss surgery
This study looks at special markers in the blood to better understand and predict a fatty liver condition called NAFLD. It focuses on people who are very overweight and are already planning to have weight-loss surgery.
TriesteAges 18–65
Hear when a new Type 2 diabetes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for type 2 diabetes?
- Yes. Clin2 currently lists 1,079 recruiting type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.