Clinical trials
Vagus Nerve Stimulation clinical trials
Below are recruiting vagus nerve stimulation clinical trials, each written for real people, not researchers. We’re tracking 158 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07719387Enrolling by invitation
Vagus nerve stimulation to boost thinking and learning after stroke
This study tests if vagus nerve stimulation, delivered through an implanted device, can help improve thinking and learning in people who have had a stroke. You would use the device at home for six weeks.
Stony Brook, New YorkAges 22 years+ - NCT07629687Recruiting
Ear Nerve Stimulation for Balance After Stroke
This trial tests a non-invasive device that stimulates a nerve in your ear to help improve balance and body control after stroke. It may help you regain stability and reduce symptoms like muscle tightness.
Islamabad, Punjab ProvinceAges 18–70 - NCT07711353Recruiting
Nerve stimulation plus physical therapy for frozen shoulder
This trial tests whether adding a gentle nerve stimulation device to standard physical therapy helps people with frozen shoulder (adhesive capsulitis) recover better. The stimulation is applied to the ear and is designed to be safe and non-invasive.
Istanbul, IstanbulAges 18–65 - NCT07337226Recruiting
Vagus nerve stimulation and treadmill training for Parkinson's walking
This study tests whether a mild electrical stimulation on the ear (called taVNS) combined with treadmill walking can improve walking ability in people newly diagnosed with Parkinson's disease. The goal is to see if this combination helps you walk better and more safely.
Roma, RMAges 50–80 - NCT04099992Recruiting
Mindfulness program for people with chronic kidney disease
This trial tests whether a mindfulness-based program can help people living with moderate-to-advanced kidney disease. It may improve how you feel day-to-day and how you manage symptoms, while researchers track kidney-related health and safety.
Atlanta, GeorgiaAges 40–80 - NCT04177511Recruiting
Vagus nerve ear stimulation for endometriosis pelvic pain
This trial tests whether stimulating a nerve through the ear (non-surgical, through the skin) can reduce chronic pelvic pain from endometriosis. It may help if standard care hasn’t fully controlled symptoms like painful periods or pain during sex.
Suresnes, Île-de-France RegionAges 15 years+ - NCT04415203Recruiting
Treatment for frequent extra heartbeats using a simple patch
This trial tests a non-surgery treatment (using a skin patch) for people who have frequent extra heartbeats coming from the heart’s lower chambers. It’s meant to see whether the patch reduces symptoms or abnormal heart rhythm compared with usual care.
Beijing, Beijing MunicipalityAges 18–75 - NCT04557618Recruiting
Ear nerve stimulation after a brain bleed
This trial studies whether stimulating a nerve near the ear (auricular VNS) can help after a spontaneous subarachnoid hemorrhage, a type of bleeding around the brain. If you qualify, you may receive the ear stimulation as an added treatment while doctors monitor your recovery.
St Louis, MissouriAges 18 years+ - NCT04673643RecruitingPhase 2
Nerve stimulation for dry eye symptoms
This Phase 2 study tests a device that delivers gentle stimulation to a nerve near the ear to help improve dry eye disease. It may help reduce dryness and discomfort, if you meet the study’s health and safety requirements.
BeijingAges 18–65 - NCT04774705Recruiting
Noninvasive vagus nerve stimulation for sepsis in the ICU
This study tests whether a noninvasive device that stimulates the vagus nerve can help adults with sepsis in the intensive care unit. Researchers want to see if adding this treatment improves outcomes compared with standard ICU care.
GarchesAges 18 years+ - NCT05272488Recruiting
Manual therapy plus vagus nerve stimulation for jaw muscle pain
This trial tests whether combining hands-on jaw treatment with a vagus nerve stimulator can reduce jaw muscle pain and improve jaw movement. It may help people whose jaw pain has been present recently and who have not had recent physiotherapy.
Alcalá de Henares, MadridAges 18 years+ - NCT05664854Recruiting
Vagus nerve stimulation guided by body imaging
This study uses a painless body scan method (electrical impedance imaging) and a targeted vagus nerve stimulation to see if it helps people with conditions that might respond to this kind of nerve treatment. If you may benefit from vagus nerve stimulation, this trial may help doctors learn whether the approach is effective and safe for you.
London, Greater LondonAges 18 years+ - NCT05866471RecruitingPhase 1
Testing nerve stimulation plus psilocybin for emotional well-being
This early safety study tests whether stimulating a nerve (taVNS) combined with psilocybin can change emotional well-being. It also checks safety issues like heart rhythms, lab results, and whether fMRI brain scans are possible.
Madison, WisconsinAges 18–70 - NCT05952674Recruiting
Vagus nerve stimulation for long-term depression symptoms
This trial studies whether a device that stimulates the vagus nerve (VNS) can help people with treatment-resistant depression or related mood disorders that have not improved despite multiple therapies. It may help by targeting mood symptoms when other treatments haven’t worked well.
Angers, FranceAges 18 years+ - NCT05981183Recruiting
Vagus nerve stimulation for chronic kidney disease
This study tests a device that gently stimulates a nerve in your ear to see if it can help people with chronic kidney disease (CKD). The device is non-invasive and may improve how your body handles kidney-related issues.
New York, New YorkAges 18–80 - NCT06009159Recruiting
Vagus nerve stimulation for fibromyalgia pain
This trial tests if a non-invasive device that stimulates the vagus nerve can help reduce pain in people with fibromyalgia. It is a potential treatment option for those who have had persistent pain for at least three months.
Boston, MassachusettsAges 18–80 - NCT06095297Recruiting
Cognitive rehab for brain fog from long COVID
This study tests a computer-based cognitive training program combined with a gentle nerve stimulation device to see if it can improve brain fog and daily functioning in people with long COVID. If you're struggling with thinking, memory, or concentration after COVID, this might help.
Birmingham, AlabamaAges 18 years+ - NCT06303960RecruitingEarly Phase 1
Brain stimulation for chronic stroke arm recovery
This early-phase trial tests whether brain stimulation (deep brain stimulation in the cerebellum or vagus nerve stimulation) can help improve arm and hand movement in people who had a stroke 1 to 3 years ago.
Jinan, ShandongAges 30–75 - NCT06304389Recruiting
Blue light therapy for epilepsy with vagus nerve stimulation
This trial tests if blue light exposure can improve the effects of vagus nerve stimulation (VNS) in people with epilepsy that is hard to control. It also includes some healthy volunteers for comparison. The goal is to find new ways to make VNS work better.
Woluwe-Saint-LambertAges 18–60 - NCT06374693Recruiting
Nerve stimulation after brain aneurysm repair
This trial tests whether a gentle nerve stimulation device (tVNS) applied to the ear is safe and practical for patients recovering from a specific type of brain bleed. It aims to see if this non-invasive treatment might help recovery after the aneurysm is repaired.
Sheffield, South YorkshireAges 18 years+ - NCT06399653Recruiting
Nerve stimulation for alcohol use disorder in veterans
This study tests a non-invasive device that gently stimulates a nerve in your neck (the vagus nerve) to see if it can help reduce alcohol cravings and improve daily functioning. It is designed for veterans who struggle with heavy drinking and want to explore a new treatment option.
San Diego, CaliforniaAges 21–65 - NCT06403475Recruiting
Vagus nerve stimulation for aphasia after stroke
This study tests whether a gentle electrical stimulation on the skin of the ear (called tVNS) can help improve word finding in people with aphasia after a stroke. You will use a computer speech program while receiving the stimulation or a placebo.
SheffieldAges 18 years+ - NCT06409338Recruiting
Ear nerve stimulation for Parkinson's motor symptoms
This study tests whether a gentle nerve stimulation on the ear (taVNS) can improve movement symptoms in Parkinson's disease. It aims to understand how this stimulation affects the brain.
Nanjing, JiangsuAges 40–80 - NCT06473623Recruiting
Ear-based nerve stimulation for autism
This trial tests a new, non-invasive way to stimulate the vagus nerve using a gentle device on the ear. The goal is to see if it can help improve social and communication symptoms in children and young adults with autism.
Tai PoAges 7–26
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Common questions
- Are there clinical trials for vagus nerve stimulation?
- Yes. Clin2 currently lists 158 recruiting vagus nerve stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vagus nerve stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vagus nerve stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.