Clinical trials
Venous Leg clinical trials
Below are recruiting venous leg clinical trials, each written for real people, not researchers. We’re tracking 51 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06798766Recruiting
Understanding darker skin tones and vein disease care
This study looks at how people with darker skin tones experience chronic venous insufficiency (a condition that affects blood flow in the legs) and aims to improve how it's diagnosed and treated. It involves two parts: one is sharing your experience through an interview, and the other includes a skin check and photos at the hospital.
London, LondonAges 18 years+ - NCT04737941Recruiting
Study of treatment for leg ulcers from weak leg veins
This study looks at people with a healing or healing-worsening leg ulcer caused by weak veins (venous reflux). It may help improve care for this common type of ulcer and reduce time to healing by testing an approach for venous ulcers.
HelsinkiAges 18 years+ - NCT05588583Recruiting
Tracking drainage from chronic leg or foot ulcers with a dressing
This study follows how much fluid (drainage) a chronic ulcer produces over time using a dressing called Mepilex Up. It may help clinicians better understand how this dressing manages “exuding” ulcers on the leg or foot.
Castro Valley, CaliforniaAges 18 years+ - NCT07048054RecruitingPhase 1/Phase 2
Patch of fat cells for chronic leg ulcers
This trial tests a patch made from your own fat cells (called TrophiPatch) to see if it helps heal chronic leg ulcers. It is for people with venous leg ulcers or diabetic foot ulcers that are not healing well with standard care.
GenevaAges 18 years+ - NCT07362719Recruiting
Thermal cure for severe leg vein problems
This study tests if a 3-week thermal spa treatment can improve symptoms of severe chronic venous insufficiency (vein problems in your legs that cause swelling, skin changes, and risk of leg ulcers). It may help if you have serious vein issues but no open ulcers.
AmnévilleAges 18 years+ - NCT02280733Recruiting
Chronic wound registry for real-world care documentation
This study is a real-world registry that collects information about chronic wounds and ulcers as they’re treated in everyday settings. It may help improve how care is tracked and supported, even if you don’t get a new medicine from the study.
The Woodlands, TexasAges Any age - NCT06568627RecruitingPhase 3
Testing a gel for cleaning leg ulcers
This study tests a new gel that helps remove dead tissue from venous leg ulcers. Venous leg ulcers are open sores on the leg that happen when veins don't work well. The gel is applied to the ulcer to clean it and help it heal. You may be able to join if you are an adult with a venous leg ulcer that is not too large and has been there for a few weeks.
Phoenix, ArizonaAges 18 years+ - NCT04920253Recruiting
Testing a water-jet treatment to heal certain foot and leg wounds
This trial tests a new “micro water jet” device (Debritom+) to help heal specific hard-to-heal wounds in people who can attend frequent visits. If you qualify, you’ll be assigned to the device treatment or standard care and monitored to see how well the wound heals.
Bradenton, FloridaAges 18 years+ - NCT06236750Recruiting
Testing a human tissue wound covering for hard-to-heal ulcers
This study is testing a special wound covering made from donated human tissue (amnion/chorion membrane) to see if it helps heal stubborn diabetic foot ulcers or venous leg ulcers that haven't improved with standard care. The covering is placed on the wound to help it heal.
Kobe, HyōgoAges Any age - NCT06300762Recruiting
Wound dressing for leg ulcers
This trial tests a new wound dressing for leg ulcers. It aims to see if the dressing helps manage fluid and heal the ulcer better than standard care. You may be a candidate if you have a leg ulcer that needs compression therapy.
Melle, NiedersachstenAges 18 years+ - NCT07342049Recruiting
Negative pressure therapy with silver for chronic leg wounds
This trial tests a special wound vacuum system with silver to treat chronic leg ulcers that show signs of infection. It aims to see if this dressing helps clean and heal wounds better.
Santiago, Santiago MetropolitanAges 18 years+ - NCT06515093Recruiting
New skin grafts for diabetic foot and venous leg ulcers
This study tests two new skin graft products (PelloGraft for diabetic foot ulcers and SanoGraft for venous leg ulcers) to see if they heal wounds faster than standard care. If you have a hard-to-heal foot or leg ulcer, this trial may offer a new option.
Vista, CaliforniaAges 18 years+ - NCT06528873RecruitingPhase 4
COMS light therapy for chronic leg ulcers
This study tests a special light therapy called COMS to help heal chronic leg ulcers. It is for people with venous leg ulcers or mixed ulcers also involving artery disease, and aims to see if the treatment improves wound closure.
GrazAges 18 years+ - NCT06606210Recruiting
Testing a pig skin wound treatment for hard-to-heal leg ulcers
This trial tests if adding a special wound dressing made from pig placenta to standard care helps heal leg ulcers faster than standard care alone. You may qualify if you have a leg ulcer that has not shown much improvement in the last 4 weeks.
North Port, FloridaAges 21 years+ - NCT06939673Recruiting
Miro3D wound matrix for healing wounds and ulcers
This trial tests a special wound dressing called Miro3D that helps heal open wounds and ulcers. It may be a good option if you have a wound that is not healing, especially if it has tunnels or pockets under the skin.
Coconut Creek, FloridaAges 18 years+ - NCT07046767Recruiting
Amnion grafts for slow-healing leg or foot ulcers
This trial tests if a special graft made from amniotic tissue can help heal chronic leg or foot ulcers that haven't improved much in the last month. It may be an option if you have a non-healing venous leg ulcer or diabetic foot ulcer that still shows some signs of healing.
Oxnard, CaliforniaAges 18 years+ - NCT07172893RecruitingPhase 4
Dermabind TL for diabetic foot ulcers
This trial tests a new wound dressing called DermaBind TL for people with diabetic foot ulcers. It aims to see if the dressing helps heal these wounds, which can be hard to treat.
DeLand, FloridaAges 18–80 - NCT07541196Recruiting
PAW-Hydrogel treatment for long-lasting wound healing
This study tests a special gel called PAW-Hydrogel to help heal chronic wounds (wounds that have not closed after 3+ months). The gel may help wounds close faster by supporting the natural healing process.
Ocoyoacac, State of MexicoAges 18 years+ - NCT06384183Enrolling by invitation
Real-world fish skin graft registry study
This study tracks how well a fish skin graft (Kerecis) heals wounds in real patients. It helps doctors learn more about who benefits most from this treatment.
Sarasota, FloridaAges Any age - NCT06328010Enrolling by invitation
Real-world data registry for wound care treatments
This study collects information on various wound types and how they respond to standard care. It aims to learn what works best for wounds that haven't healed after 4 weeks of treatment.
Scottsdale, ArizonaAges 18 years+ - NCT06180902Recruiting
Testing fluid response methods in patients with reduced consciousness
This trial compares different ways to check if a patient in the ICU with lowered consciousness needs more IV fluids. It aims to find the most accurate method, which could help doctors give the right amount of fluid.
MoscowAges 18 years+ - NCT06693245Recruiting
Pain during microwave treatment for varicose veins
This study looks at how much pain people feel during a microwave treatment for varicose veins in the leg. It aims to understand what factors affect pain, so the treatment can be more comfortable for future patients.
Chengdu, SichuanAges 18–90 - NCT06711120Recruiting
Comparing two treatments for varicose veins in the lower legs
This study compares two minimally invasive treatments (radiofrequency ablation and microwave ablation) for varicose veins in the small saphenous vein. If your varicose veins cause symptoms like pain, swelling, or heaviness, this trial may help determine which treatment works better.
ChengduAges 18–90 - NCT07335341Recruiting
Liberant thrombectomy system case survey
This survey collects feedback from doctors who used the Liberant system to remove blood clots. The results help understand how well the device works in real-life procedures.
Washington D.C., District of ColumbiaAges 22 years+
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Common questions
- Are there clinical trials for venous leg?
- Yes. Clin2 currently lists 51 recruiting venous leg studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a venous leg trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a venous leg trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.