Treatment
Anti-VEGF clinical trials
We’re tracking 19 recruiting studies that include Anti-VEGF, each written for real people, not researchers, below.
Recruiting studies
- NCT06841250Enrolling by invitation
Early eye changes after first injection for diabetic macular edema
This study looks at how the eyes of people with diabetes-related swelling in the retina change after their very first anti-VEGF injection. By measuring early changes in OCT scans, doctors hope to learn more about how well the treatment works and how to predict outcomes.
SohagAges Any age - NCT06985706RecruitingPhase 3
Comparing two treatments for diabetic eye swelling after initial injections
This trial tests whether switching from anti-VEGF injections to a special laser is better than continuing injections alone for people with diabetic macular edema whose central retinal thickness has dropped below 400 microns after the first year of treatment.
BelfastAges 18 years+ - NCT06349044Recruiting
Radiation and immunotherapy with or without probiotics for advanced digestive cancers
This trial tests if adding a probiotic (Lactobacillus rhamnosus M9) to standard radiation and immunotherapy can help people with advanced digestive system cancers. It aims to see if the combination is more effective and safer than the standard approach alone.
Hangzhou, ZhejiangAges 18–75 - NCT06537908Recruiting
Check if a new drug combo works for advanced liver cancer
This trial tests a combination of immunotherapy (anti-PD-1/PD-L1) and an anti-VEGF drug for people with advanced hepatocellular carcinoma (HCC), a type of liver cancer that cannot be removed by surgery or has spread. The goal is to see if these drugs can shrink tumors or slow the cancer's growth.
ShanghaiAges 18–90 - NCT06984822Recruiting
Comparing eye injections for diabetic macular edema
This study compares two different eye injection treatments for diabetic macular edema (DME)—a condition where fluid builds up in the center of the retina, blurring vision. Researchers want to see how certain measures in the blood and in eye scans relate to how well each treatment works.
MölndalAges 18 years+ - NCT07133438RecruitingPhase 4
Vitamin B12 with eye injections for blocked retinal vein
This trial tests if adding mecobalamin (a form of vitamin B12) to standard anti-VEGF eye injections helps people with vision loss caused by a blocked vein in the retina. You must have swelling in the back of the eye and have had no prior treatments for this condition.
ChongqingAges 18–80 - NCT07329686RecruitingPhase 1/Phase 2
Anti-VEGF Injection for Herpes-Related Corneal Blood Vessels
This study tests whether injecting an anti-VEGF medication directly into the clear part of your eye (cornea) can safely reduce abnormal blood vessels caused by a herpes virus eye infection. If you have HSV keratitis with new vessel growth and haven't had prior anti-VEGF treatment or corneal surgery, this trial may be an option for you.
Hangzhou, ZhejiangAges 18 years+ - NCT05728476Recruiting
Compare eye surgery plus peeling versus anti-VEGF injections
This trial compares a minimally invasive eye procedure (vitrectomy with peeling) versus anti-VEGF injections to treat new diabetic macular edema in people who have not had treatment yet. It looks at which option improves vision and eye swelling for people with diabetes.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06845163RecruitingPhase 2
Testing dapagliflozin for diabetic macular edema
This study tests whether a medication called dapagliflozin, which is usually used for diabetes and heart failure, can help reduce swelling in the retina (diabetic macular edema) and improve vision. It is for people with type 2 diabetes who are already taking insulin and metformin.
Alexandria, Alexandria GovernorateAges 18–85 - NCT03577041Recruiting
Cost study of eye injections for new macular degeneration
This study evaluates the cost-effectiveness of three anti-VEGF eye injection treatments (bevacizumab, ranibizumab, or aflibercept) for patients with newly diagnosed age-related macular degeneration affecting the center of vision. The research aims to understand which treatment option provides the best medical and financial value in France.
AmiensAges 18–70 - NCT07701759Recruiting
Oxygen levels during eye injections for premature babies
This study looks at how often low oxygen levels happen in premature babies when they get eye injections for a serious eye condition. The goal is to understand the risks and make the procedure safer.
BuraidahAges Any age - NCT05093374RecruitingPhase 4
AI-guided care for wet age-related macular degeneration
This Phase 4 study tests an artificial-intelligence (AI) system used in real-world care for people with “wet” age-related macular degeneration. The goal is to help doctors monitor and treat the eye more accurately and safely over time.
Vienna, State of ViennaAges 50–100 - NCT06307249RecruitingPhase 1
Precision therapy for solid tumors targeting CDK4/6 and VEGF
This trial tests a combination of two targeted drugs for advanced solid tumors like colorectal, lung, breast, and genitourinary cancers. The goal is to see if blocking certain proteins and a long RNA molecule can slow tumor growth.
Tripoli, North LebanonAges 18 years+ - NCT06517888RecruitingPhase 1/Phase 2
Gene therapy for hearing loss from vestibular schwannoma
This trial tests a gene therapy injected into the ear to slow tumor growth and prevent further hearing loss in people with a vestibular schwannoma that is getting worse. It's for those who already have severe hearing loss in the affected ear.
Baltimore, MarylandAges 18 years+ - NCT06580574RecruitingPhase 2
Immunotherapy to save the stomach or colon from surgery
This trial tests whether using immune checkpoint inhibitors alone (like checkpoint blockade drugs) can help people with certain gastric or colon cancers avoid surgery. It's for patients whose tumors have a specific genetic feature called dMMR/MSI-H and haven't spread to other parts of the body.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06610747Recruiting
Home versus hospital care for diabetic eye swelling
This study tests whether receiving anti-VEGF injections for diabetic macular edema (DME) at home is as safe and effective as getting them in the hospital. You would use a home device to check your vision and eye scans, and a nurse would visit for injections.
Dongguan, GuangdongAges 18 years+ - NCT07062055RecruitingPhase 2
A study of combination therapy for advanced liver cancer with spread
This trial tests a combination of immunotherapy (iparomlimab/tuvonralimab), a targeted drug (bevacizumab), and radiation (SBRT) plus liver-directed chemo (HAIC) for people with advanced liver cancer (HCC) that has spread to blood vessels or a few other places. It aims to see if this approach can help control the cancer.
Jinan, ShandongAges 18–70 - NCT07157969RecruitingPhase 2
Immunotherapy and anti-VEGF with or without local therapy for liver cancer
This trial tests a combination of immunotherapy (checkpoint inhibitors) and anti-VEGF therapy (which blocks blood vessel growth to tumors) with or without local treatments (like chemoembolization) for advanced liver cancer. It aims to see if the combination works better than current treatments.
BeijingAges 18 years+ - NCT07308639Recruiting
Eye disease health data study in Germany
This study looks at health records in Germany to understand how many people have certain eye conditions like age-related macular degeneration, diabetic macular edema, or retinal vein occlusion. It also tests new ways to use this information for research.
LeverkusenAges 18 years+
What Anti-VEGF is being studied for
Conditions with recruiting Anti-VEGF studies.
Common questions
- Are there clinical trials studying Anti-VEGF?
- Yes. Clin2 currently lists 19 recruiting studies that include Anti-VEGF, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Anti-VEGF trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Anti-VEGF an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Anti-VEGF or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.