Treatment
Comparator clinical trials
We’re tracking 1,699 recruiting studies that include Comparator, each written for real people, not researchers, below.
Recruiting studies
- NCT06451861RecruitingPhase 2
Testing a new drug combo for newly diagnosed AML
This trial tests a new combination of drugs (ABC-14) against the standard treatment for adults newly diagnosed with acute myeloid leukemia (AML) who haven't had intensive treatment yet. The goal is to see if the new combo works better and is safe.
Dongguan, GuangdongAges 18 years+ - NCT06447402RecruitingPhase 3
Inhaled Amphotericin B for Chronic Aspergillosis Maintenance
This study compares two inhaled treatments (amphotericin B vs. saline) to see which one works better as maintenance therapy for people with chronic pulmonary aspergillosis. It aims to find a convenient way to keep the infection under control after initial treatment.
Chandigarh, ChandigarhAges 18 years+ - NCT06447480RecruitingPhase 3
Comparing isotretinoin to standard care for moderate acne in darker skin
This trial compares oral isotretinoin (a strong acne medication) to standard treatments for people with moderate acne and darker skin tones. It aims to find which treatment works best for skin of color.
Nice, Alpes-MaritimesAges 13–30 - NCT06440759Recruiting
Filter Comparison for Septic Shock with Kidney Failure
This study compares two types of filters used during continuous kidney replacement therapy in patients with septic shock and severe acute kidney injury. The goal is to see which filter works better and is safer.
Kubang Kerian, KelantanAges 18 years+ - NCT06348719Recruiting
Robot vs. standard laparoscopy for early endometrial cancer
This trial compares two types of minimally invasive surgery (robot-assisted vs. conventional laparoscopy) for removing the uterus in people with early-stage, low- to intermediate-risk endometrial cancer. The goal is to see which approach offers the best value and outcomes.
LilleAges 18 years+ - NCT06434571RecruitingPhase 2
Comparing two sleep treatments for people with MS
This trial tests if talking with a sleep coach by video is better than a web-based program for improving sleep, reducing fatigue, and protecting the brain in people with multiple sclerosis (MS). Both treatments focus on changing thoughts and habits around sleep.
Kansas City, KansasAges 18–65 - NCT06428175Recruiting
Hospital-to-home support for children with complex needs
This study tests a program to help children with complex medical needs and their families transition smoothly from the hospital to home. It focuses on improving communication and support during that critical time.
Chapel Hill, North CarolinaAges Up to 18 years - NCT06433297Recruiting
Direct vs. indirect pulp capping for deep cavities in lower molars
This study compares two ways to treat deep cavities in lower back teeth when the nerve is exposed. The goal is to see which method better protects the nerve and avoids the need for a root canal.
Rohtak, HaryanaAges 18 years+ - NCT06432790Recruiting
In-person vs online healthy living and asthma program for kids
This study compares two programs for helping children with asthma who are overweight or obese — one that is held in person and another that is offered online. It tests whether learning about healthy habits and asthma management works better when done face-to-face or on a computer.
Boston, MassachusettsAges 4–17 - NCT06433284Recruiting
Comparing two treatments for large macular holes
This study compares two surgical methods for repairing large macular holes, a condition that affects the center of the retina and can blur vision. The goal is to see which technique works better for closing the hole and improving eyesight.
Nakhon Si Thammarat, ThasalaAges 18 years+ - NCT06433921RecruitingPhase 1
Comparing two asthma rescue inhalers with different propellants
This study compares two versions of the common asthma rescue inhaler (salbutamol/albuterol) that use different propellants (the gas that pushes the medicine out). The goal is to see if the new propellant works as well as the current one. If you have mild asthma and are on a stable treatment plan, you may be able to join.
ManchesterAges 18–65 - NCT06439082RecruitingPhase 3
Crizanlizumab for sickle cell pain crises
This trial tests whether crizanlizumab can reduce painful sickle cell crises (called vaso-occlusive crises or VOCs) in people with sickle cell disease who have frequent crises. It may be an option for those who still have crises despite current treatments.
Birmingham, AlabamaAges 12–100 - NCT06435429RecruitingPhase 3
Zanidatamab vs trastuzumab for HER2+ breast cancer
This study compares a new drug called zanidatamab against trastuzumab (Herceptin), both given with a chemotherapy of your doctor's choice. It is for people with HER2-positive breast cancer that has spread and who have already tried T-DXd treatment.
Phoenix, ArizonaAges 18 years+ - NCT06415123Enrolling by invitation
Study comparing new bone graft to standard for spinal fusion
This study tests a new bone graft material (MagnetOs Flex Matrix) compared to a standard bone graft for spinal fusion surgery. It may be an option if you have ongoing back or leg pain that hasn't improved with other treatments and you need a one-time fusion of up to 4 levels in your lower back.
Southfield, MichiganAges 18 years+ - NCT06408259RecruitingPhase 3
Comparing ozanimod and fingolimod for children with MS
This study compares two oral medications, ozanimod and fingolimod, to see which one works better and is safer for children and teenagers with relapsing-remitting MS. Both drugs help reduce MS attacks and slow down the disease.
Loma Linda, CaliforniaAges 10–17 - NCT06416410RecruitingPhase 3
Combination targeted therapy for KRAS G12C lung cancer
This trial tests a combination of two targeted drugs (JAB-21822 and JAB-3312) compared to standard chemotherapy for people with advanced non-small cell lung cancer that has a specific KRAS G12C mutation. It is for people who have not yet received any cancer treatment for their advanced disease.
Hefei, AnhuiAges 18 years+ - NCT06409910RecruitingPhase 2
Comparing shorter radiation treatments for prostate cancer
This study tests two slightly different short-course radiation schedules for men who have had their prostate removed and are now getting follow-up radiation. The goal is to see if one is more effective or has fewer side effects.
London, OntarioAges 18 years+ - NCT06405607RecruitingPhase 2
Psilocybin vs Ketamine for Alcohol Use Disorder Trial
This trial tests two psychedelic-assisted therapies, psilocybin and ketamine, to see which works better for reducing heavy drinking in people with alcohol use disorder (AUD). You'll receive either drug along with counseling, and the study monitors safety closely.
Iowa City, IowaAges 21–65 - NCT06380751RecruitingPhase 3
New targeted therapy for BRCA/PALB2-mutated HR+ breast cancer
This trial tests a new combination of targeted therapies (saruparib plus camizestrant or hormone therapy) against standard treatments for people with a specific type of advanced breast cancer. It may be a good option if you have a BRCA1, BRCA2, or PALB2 gene mutation and have not yet had treatment for your advanced disease.
Gilbert, ArizonaAges 18 years+ - NCT06397846Recruiting
Blood markers for benign vs. malignant pancreas changes
This study looks for markers in the body that can tell the difference between harmless (benign) and dangerous (malignant) pancreatic growths. It may help doctors learn more about changes in the pancreas and guide better care.
BesançonAges 18 years+ - NCT06391554Recruiting
Education and exercise for hip osteoarthritis
This study compares the effects of adding exercise to an education program for people with hip osteoarthritis. It aims to see if exercise improves pain, function, and hip joint health (measured by MRI) more than education alone.
Aarhus CAges 45 years+ - NCT06376968Recruiting
Testing a new dialysis option for low blood pressure
This study tests a new dialysis option called 'Biologic Fusion' that may help people who often have low blood pressure during dialysis. It compares this new method to standard dialysis to see if it is safer and works better.
Bologna, Emilia-RomagnaAges 18 years+ - NCT06363877RecruitingPhase 3
Testing a germ-killing rinse during abdominal surgery
This trial is testing whether a diluted povidone-iodine (a common germ-killer) rinse inside the belly during surgery can prevent infections better than a plain saltwater rinse. It is for adults having abdominal surgery for certain types of wounds.
Loma Linda, CaliforniaAges 18–80 - NCT06376916RecruitingPhase 3
Testing magnesium doses for fast heart rate in atrial fibrillation
This trial tests whether giving a higher dose of magnesium (4 grams) compared to a lower dose (2 grams) or a placebo can help control a fast heart rate during atrial fibrillation. It may help patients who are already receiving diltiazem.
Oak Lawn, IllinoisAges 18 years+
Common questions
- Are there clinical trials studying Comparator?
- Yes. Clin2 currently lists 1,699 recruiting studies that include Comparator, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Comparator trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Comparator an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Comparator or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.